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CDK2和P53在细胞中心体复制与调控中的作用

文献类型: 中文期刊

作者: 聂昊;杜卫华;郝海生;王宗礼;王栋;朱化彬

作者机构:

关键词: CDK2;P53;中心体;复制调控

期刊名称:中国畜牧兽医

ISSN: 1671-7236

年卷期: 2008 年 35 卷 12 期

页码: 105-109

收录情况: 北大核心

摘要: 中心体是真核生物重要的细胞器,其复制与调控异常可能是体外胚胎发育异常的重要原因,而CDK2和P53是调控中心体复制的关键且必要因子,在细胞中心体复制调控中起核心作用。作者简要介绍了中心体的功能和复制过程,重点综述了CDK2、P53及其相关因子在中心体复制调控中的作用,对研究体外受精胚胎和克隆胚胎的发育异常具有一定的理论意义。

分类号: Q343

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