Phytotoxicity of fluridone and emerging transformation products in agricultural soils: Insights into molecular interactions and photosynthetic disruptions in maize
文献类型: 外文期刊
作者: Feng Chen;Chi Wu;Yuzhu Wang;Olga A. Glazunova;Konstantin V. Moiseenko;Lan Zhang;Liangang Mao;Lizhen Zhu;Xingang Liu
作者机构:
关键词: Fluridone;Molecular docking;Phytotoxicity;Soil degradation;Transformation product
期刊名称: Journal of Hazardous Materials
ISSN: 0304-3894
年卷期: 2025 年 496 卷
页码:
收录情况: SCIE(2025版) ; ; EI(2025版)
摘要: The environmental presence of herbicides and their transformation products (TPs) in soil poses a significant risk to crop rotation systems. Fluridone, a widely used carotenoid biosynthesis inhibitor, has been linked to phytotoxic effects in subsequent crops, yet the contribution of its TPs remains poorly understood. This study systematically investigated the soil transformation of fluridone in three representative Xinjiang soils, revealing half-lives ranging from 39.6 to 89.5 days. Additionally, a high-resolution mass spectrometry (HRMS) based nontarget screening workflow identified five TPs derived from fluridone in soil, including a novel metabolite (TP297) confirmed via authentic standard. Structural elucidation suggested key transformation pathways involving oxidation and cleavage, decarboxylation, hydroxylation, and N-demethylation. Docking and Molecular Dynamics (MD) simulations revealed that fluridone and TP297 exhibited the strongest binding affinities to phytoene desaturase (PDS) (-23.15 ± 2.37 and −26.57 ± 3.02 kcal/mol, respectively), suggesting a high potential for bioactivity retention. Pot experiments further confirmed TP297-induced phytotoxicity in maize seedlings, characterized by leaf bleaching, impaired photosystem II function, and disrupted chloroplast biogenesis. These findings underscore the necessity of TP-inclusive risk assessments in agrochemical regulation and provides critical insights for mitigating carryover toxicity in sustainable agriculture.
分类号:
- 相关文献
作者其他论文 更多>>
-
Comparative study on the ecotoxicity of nanoformulated and conventional emamectin benzoate to Raphidocelis subcapitata: A mechanistic disparity analysis
作者:Jin Yang;Yiming Chang;Ruiqiang Fu;Man Li Yu;Lan Zhang;Liangang Mao;Lizhen Zhu;Chi Wu;Yanning Zhang;Xingang Liu
关键词:Algae;Emamectin benzoate;Microemulsions;Nano-size effect;Toxic mechanism
-
Transgenerational combined toxicity effects of neonicotinoids and triazole pesticides at environmentally relevant concentrations on D. magna: From individual to population level
作者:Chi Wu;Kai He;Huizhen Li;Lan Zhang;Liangang Mao;Lizhen Zhu;Jinhua Jiang;Xingang Liu
关键词:Combined toxicity;Environmental concentration;Pesticides;Population dynamics;Transgenerational effects
-
Genome-Wide Identification and Expression Analysis of Phytosulfokine Peptide Hormone Genes in Camellia sinensis
作者:Fengshui Yang;Lan Zhang;Qiuying Lu;Qianying Wang;Yanjun Zhou;Qiuhong Wang;Liping Zhang;Kai Shi;Shibei Ge;Xin Li
关键词:Camellia sinensis;gene expression;genome-wide analysis;phytosulfokine;stress response
-
Combined use of 1,3-dichloropropene with dimethyl disulfide and chloropicrin for managing potato powdery scab and weed
作者:Liangang Mao;Haojie Shi;Muhammad Umair Sial;Ruifeng Guo;Lan Zhang;Yanning Zhang;Lizhen Zhu;Chi Wu;Xingang Liu
关键词:potato powdery scab; weed; soil fumigant; soilborne pests
-
Exploration of the biodiversity and mining novel target genes of Listeria monocytogenes strains isolated from beef through comparative genomics analysis
作者:Bo Zhang;Wenjie Sun;Xiaoxu Wang;Honglin Ren;Yang Wang;Shaohui Hu;Chengwei Li;Yuzhu Wang;Jiaqi Hou;Xueyu Hu;Ruoran Shi;Yansong Li;Shiying Lu;Qiang Lu;Zengshan Liu;Pan Hu
关键词:comparative genomics;genetic evaluations;Listeria monocytogenes;pan-genomics;target genes
-
Lignin Metabolism Is Crucial in the Plant Responses to Tambocerus elongatus (Shen) in Camellia sinensis L.
作者:Wenli Wang;Xiaogui Zhou;Qiang Hu;Qiuhong Wang;Yanjun Zhou;Jingbo Yu;Shibei Ge;Lan Zhang;Huawei Guo;Meijun Tang;Xin Li
关键词:Camellia sinensis;flavonoids;insect pest;jasmonic acid;lignin;phenylpropanoid pathway;plant defense
-
Deep Amplicon Sequencing Reveals Culture-dependent Clonal Selection of Mycobacterium tuberculosis in Clinical Samples
作者:Jiuxin Qu;Wanfei Liu;Shuyan Chen;Chi Wu;Wenjie Lai;Rui Qin;Feidi Ye;Yuanchun Li;Liang Fu;Guofang Deng;Lei Liu;Qiang Lin;Peng Cui
关键词:(2-1-2)Culture-dependent;Culture-free;Deep amplicon sequencing;Drug susceptibility testing;Mycobacterium tuberculosis