数字农科院2.0

Genetic Evolution Analysis Of 2019 Novel Coronavirus And Coronavirus From Other Species

文献类型: 外文期刊

作者: Li, C; Yang, YL; Ren, LZ

作者机构:

关键词: Severe Acute Respiratory Syndrome Coronavirus 2 (Sars-Cov-2); Genome; Genetic Evolution; Structural Protein; 2019 Coronavirus Disease (Covid-19)

期刊名称: INFECTION GENETICS AND EVOLUTION

ISSN: 1567-1348

年卷期: 2020 年 82 卷

页码:

收录情况: JCR(2021版)

摘要: The Corona Virus Disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARSCoV-2) is a Public Health Emergency of International Concern. However, so far, there are still controversies about the source of the virus and its intermediate host. Here, we found the novel coronavirus was closely related to coronaviruses derived from five wild animals, including Paguma larvata, Paradoxurus hermaphroditus, Civet, Aselliscus stoliczkanus and Rhinolophus sinicus, and was in the same branch of the phylogenetic tree. However, genome and ORF1a homology show that the virus is not the same coronavirus as the coronavirus derived from these five animals, whereas the virus has the highest homology with Bat coronavirus isolate RaTG13.

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