RD21 enhances resistance to the strawberry vein banding virus by promoting autophagy-mediated degradation of the viral silencing suppressor P6 protein
文献类型: 外文期刊
作者: Yang, Xianchu;Feng, Jiying;Xu, Kai;Han, Jincheng;Zhang, Minghui;Cheng, Aiwen;Wang, Zhanqi;Wang, Fang;Zhou, Xueping;Jiang, Lei;Jiang, Tong
作者机构:
关键词: strawberry vein banding virus (SVBV) P6;Fragaria vesca;responsive to desiccation 21 (RD21);autophagy
期刊名称: PLANT BIOTECHNOLOGY JOURNAL
ISSN: 1467-7644
年卷期: 2025 年
页码:
收录情况: SCIE(2025版)
摘要: Responsive to desiccation 21 (RD21) is a papain-like cysteine protease (PLCP). PLCPs are involved in plant growth and development, as well as stress and plant immune responses. Currently, few studies have reported on the involvement of PLCPs in defence against viral infections. Here, we show that RD21 of strawberry (Fragaria vesca) interacts with the strawberry vein banding virus (SVBV) P6 protein. SVBV infection induces FvRD21 expression. Subcellular localization revealed that FvRD21 and P6 colocalize in the perinuclear and cytoplasmic regions. Further analysis showed that FvRD21 overexpression induces the autophagy pathway that degrades the P6 protein, destroys the function of P6 as a viral suppressor of RNA silencing (VSR), inhibits the pathogenicity of P6, and confers resistance to SVBV in strawberry plants. Moreover, mutant FvRD21(H300A) lost its ability to interact with SVBV P6 and did not affect P6 accumulation and VSR function. Additionally, abscisic acid (ABA) pretreatment of strawberry plants promoted FvRD21 upregulation and inhibited SVBV infection, and FvRD21 overexpression activated the ABA pathway. In summary, FvRD21 inhibits SVBV infection by degrading SVBV P6 through the autophagy pathway. Hence, this study provides a novel report on the defence strategy of strawberry plants against SVBV infections.
分类号:
- 相关文献
作者其他论文 更多>>
-
Heat-Inactivated Selenium Nanoparticle-Enriched Lactobacillus Enhance Mucosal IgA Responses and Systemic Responses of Clostridium perfringens Multi-Epitope Vaccine Correlated with TGF-β and NF-κB Pathways in Mice
作者:Zhou, Xinyao;Jia, Zheng;De, Xinqi;Yang, Zaixing;Li, Yifan;Liu, Runhang;Niu, Lingdi;Yao, Xinran;Jiang, Yuxuan;Wang, Fang;Ge, Junwei
关键词:nano selenium;probiotics;multi-epitope vaccine;mucosal IgA;adjuvant
-
Lysinibacillus macroides 38352 isolated from traditional Chinese fermented foods: a dual effect on ochratoxin A detoxification and immune suppression alleviation
作者:Wang, Jiaqing;Duan, Haoyuan;Zhang, Wenzhi;Li, Hai;Yang, Zaixing;Zhang, Chuankun;Zhang, Shuhe;Guo, Junjie;Ge, Junwei;Wang, Fang;Gao, Mingchun
关键词:OTA;biodegradation;Lysinibacillus macroides 38352;broiler;vaccine efficacy
-
Molecular Identification and Pathogenicity of a Chilli Veinal Mottle Virus Isolate from Sichuan, China
作者:Chen, Cheng;Lu, Daihua;Lin, Xiaotong;Zhou, Xueping;Yang, Xiuling
关键词:phylogenetic analysis;recombination analysis;infectious clone;infectivity;NIb
-
Editing of an antiviral host factor boosts plant growth and yield of plant viral vector-mediated heterologous protein expression
作者:Fang, Zhu;Zhao, Xinru;Du, Min;Xu, Xinyi;Zhou, Hui;Guo, Wei;Zhou, Xueping;Yang, Xiuling
关键词:Nicotiana benthamiana;antiviral host factor;genome editing;plant biofactory
-
Regulation of Anthocyanins and Quality in Strawberries Based on Light Quality
作者:Wang, Fang;Wang, Jingxuan;Ji, Guangsi;Kang, Xinna;Li, Yali;Hu, Jiangtao;Qian, Chun;Wang, Sen
关键词:strawberry;light quality;anthocyanin;color;flavor
-
Cucumber green mottle mosaic virus encodes additional small proteins with specific subcellular localizations and virulence function
作者:Gong, Pan;Gao, Mengxin;Chen, Yalin;Zhang, Mingzhen;Huang, Yucong;Hu, Xiaohua;Zhao, Siwen;Zhang, Hui;Pan, Mengjiao;Cao, Buwei;Shen, Qingtang;Liu, Yong;Lozano-Duran, Rosa;Wang, Aiming;Zhou, Xueping;Li, Fangfang
关键词:positive-sense single-stranded RNA viruses;tobamoviruses;cucumber green mottle mosaic virus;small ORFs;peroxisomes;virus pathogenicity
-
A virulent escherichia coli O121-B2-ST131 strain causes hemorrhagic pneumonia in mink: evidence from pathogenicity and animal challenge experiments
作者:Lin, Yumeng;Wang, Fang;Ma, Dexing;Wen, Shanshan;Wang, Xiaoyan;Yang, Jiamei;Guan, Zhenhong;Chen, Hongyan;Ge, Junwei;Zhao, Lili
关键词:Escherichia coli;Extraintestinal pathogenic E. coli;Hemorrhagic pneumonia;Mink diseases;Phylogenetic analysis;Virulence factors