数字农科院2.0

Research Progress on the Chemical Constituents and Pharmacological Effects of Houttuynia cordata Thunb and a Predictive Analysis of Quality Markers

文献类型: 外文期刊

作者: Zhuo Yang;Peng Ji;Chenchen Li;Fanlin Wu;Yongli Hua;Yanming Wei;Yuxia Cao

作者机构:

关键词: chemical constituents;H. cordata;pharmacological action;quality marker;research progress

期刊名称: Current Issues in Molecular Biology

ISSN: 1467-3037

年卷期: 2025 年 47 卷 1 期

页码:

收录情况: SCIE(2025版)

摘要: Houttuynia cordata (H. cordata) is widely used in respiratory disease control as an important heat-clearing and detoxifying traditional Chinese medicine. It effectively clears away heat and toxins, eliminates carbuncles, and drains pus, and it is diuretic and detoxicating. The aim of this study is to review the botany, chemical composition, pharmacological effects, and quality control of H. cordata to establish a better-quality evaluation system. Google Scholar, Baidu Scholar, PubMed, ScienceDirect, Web of Science, and multiple databases, including China National Knowledge Infrastructure (CNKI) and Wanfang Data, were searched. A structural diagram of the compound was drawn using ChemDraw software. H. cordata contains volatile oils, flavonoids, and alkaloids. It has antibacterial, anti-inflammatory, antiviral, antioxidant, antitumor, and immunity-enhancing pharmacological effects. By analyzing the literature, it was predicted that Houttuynia sodium, methyl nonyl ketone, quercetin, and quercitrin could be used as the quality markers (Q-marker) of H. cordata. This provides a basis for further research into the applications of H. cordata.

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