数字农科院2.0

Lactiplantibacillus plantarum FRT4 attenuates high-energy low-protein diet-induced fatty liver hemorrhage syndrome in laying hens through regulating gut-liver axis

文献类型： 外文期刊

作者： Li D.;Cai H.;Liu G.;Han Y.;Qiu K.;Liu W.;Meng K.;Yang P.

作者机构：

关键词： Fatty liver hemorrhage syndrome;Gut microbiota;Lactiplantibacillus plantarum FRT4;Laying hens;Lipid metabolism

期刊名称： Journal of Animal Science and Biotechnology

ISSN： 1674-9782

年卷期： 2024 年 15 卷 1 期

页码：

收录情况： SCIE（2024版） ; ; CSCD（2023-2024年度） ; ; 科技核心（2024版） ; ; 农林核心（2020版）

摘要： Background: Fatty liver hemorrhage syndrome (FLHS) becomes one of the most major factors resulting in the laying hen death for caged egg production. This study aimed to investigate the therapeutic effects of Lactiplantibacillus plantarum (Lp. plantarum) FRT4 on FLHS model in laying hen with a focus on liver lipid metabolism, and gut microbiota. Results: The FLHS model of laying hens was established by feeding a high-energy low-protein (HELP) diet, and the treatment groups were fed a HELP diet supplemented with differential proportions of Lp. plantarum FRT4. The results indicated that Lp. plantarum FRT4 increased laying rate, and reduced the liver lipid accumulation by regulating lipid metabolism (lipid synthesis and transport) and improving the gut microbiota composition. Moreover, Lp. plantarum FRT4 regulated the liver glycerophospholipid metabolism. Meanwhile, “gut-liver” axis analysis showed that there was a correlation between gut microbiota and lipid metabolites. Conclusions: The results indicated that Lp. plantarum FRT4 improved the laying performance and alleviated FLHS in HELP diet-induced laying hens through regulating “gut-liver” axis. Our findings reveal that glycerophospholipid metabolism could be the underlying mechanism for the anti-FLHS effect of Lp. plantarum FRT4 and for future use of Lp. plantarum FRT4 as an excellent additive for the prevention and mitigation of FLHS in laying hens. © The Author(s) 2024.

分类号：

  • 相关文献

[1]Lactiplantibacillus plantarum FRT4 protects against fatty liver hemorrhage syndrome: regulating gut microbiota and FoxO/TLR-4/NF-κB signaling pathway in laying hens. Daojie Li,Kun Meng,Guohua Liu,Zhiguo Wen,Yunsheng Han,Weiwei Liu,Xin Xu,Liye Song,Hongying Cai,Peilong Yang. 2025

[2]Heat-Inactivated Lactiplantibacillus plantarum FRT4 Alleviates Diet-Induced Obesity via Gut-Liver Axis Reprogramming. Huang, Yuyin,Wang, Qingya,Han, Xiling,Meng, Kun,Liu, Guohua,Zhang, Haiou,Zhang, Rui,Cai, Hongying,Yang, Peilong. 2025

[3]Effects of chili meal supplementation on productive performance, intestinal health, and liver lipid metabolism of laying hens fed low-protein diets. Yudi Xiao,Mingming Ai,Junhong Miao,Shuhui Yan,Yifan Du,Junmin Zhang,Chaohua Tang,Kai Zhang. 2025

[4]Effects of Dietary Bopu Powder Supplementation on Serum Antioxidant Capacity, Egg Quality, and Intestinal Microbiota of Laying Hens. Hua Liu,Qian Lin,Xiubin Liu,Peng Huang,Zihui Yang,Manhu Cao,Mengting Liu,Xinyao Li,Jianguo Zeng,Jianhua He. 2022

[5]Clostridium autoethanogenum protein inclusion in the diet for broiler: Enhancement of growth performance, lipid metabolism, and gut microbiota. Yushan Wu,Jing Wang,Ming Jia,Shixin Huang,Ying Cao,Ting Yao,Junguo Li,Yuxin Yang,Xu Gu. 2022

[6]Dosage of Dual-Protein Nutrition Differentially Impacts the Formation of Atherosclerosis in ApoE−/− Mice. Yingchun Huang,Kun Zhang,Li Zhang,Juhui Qiu,Lin Fu,Tieying Yin,Jing Wang,Rui Qin,Jingjie Zhang,Xianwen Dong,Guixue Wang. 2022

[7]Depletion of Gut Microbiota Inhibits Hepatic Lipid Accumulation in High-Fat Diet-Fed Mice. Han, Hui,Wang, Mengyu,Zhong, Ruqing,Yi, Bao,Schroyen, Martine,Zhang, Hongfu. 2022

[8]Effects of Oats, Tartary Buckwheat, and Foxtail Millet Supplementation on Lipid Metabolism, Oxido-Inflammatory Responses, Gut Microbiota, and Colonic SCFA Composition in High-Fat Diet Fed Rats. Yong Wang,Wentao Qi,Xiaoxuan Guo,Ge Song,Shaojie Pang,Wei Fang,Zhenzhen Peng. 2022

[9]Nuclease treatment enhanced the ameliorative effect of yeast culture on epidermal mucus, hepatic lipid metabolism, inflammation response and gut microbiota in high-fat diet-fed zebrafish. Yajie Zhao,Qiang Hao,Qingshuang Zhang,Yalin Yang,Chao Ran,Qiyou Xu,Chenglong Wu,Wenshu Liu,Siming Li,Zhen Zhang,Zhigang Zhou. 2022

[10]Addition of solid-state fermentation product of yeast ameliorated the effects of high-fat diet on hepatic lipid metabolism, epidermal mucus, intestine and liver health, and gut microbiota of zebrafish. Jie Li,Dongmei Xia,Xiufang Jing,Yajie Zhao,Qiang Hao,Qingshuang Zhang,Mingxu Xie,Yalin Yang,Chao Ran,Qiyou Xu,Chenglong Wu,Zhen Zhang,Zhigang Zhou. 2023

[11]Effect of dietary supplementation with sanguinarine on meat quality and lipid metabolism of broilers. Yue Su,Peng Huang,Zhiyong Wu,Wanwan Dai,Yan Zhang,Jianguo Zeng. 2024

[12]Growth performance, lipid metabolism, and systemic immunity of weaned piglets were altered by buckwheat protein through the modulation of gut microbiota. Weilong Tu,Wansen Nie,Xiaohui Yao,Junjie Zhang,Hailong Zhang,Di Di,Zongjie Li. 2024

[13]Lactobacillus plantarum L11 and Lactobacillus reuteri LR: Ameliorate Obesity via AMPK Pathway. Shukun Liang,Jintao Sun,Xinshu Gu,Ya Zhao,Xiumin Wang,Hui Tao,Zhenlong Wang,Yougang Zhong,Jinquan Wang,Bing Han. 2025

[14]Propolis Modulates the Gut Microbiota-Gut Hormone-Liver AMPK Axis to Ameliorate High-Fat Diet-Induced Metabolic Disorders in Rats. Sun, Yanru,Huang, Wanwan,Shang, Yingying,El-Din, Mohamed G. Sharaf,Hang, Hua,Wang, Peng,Zhang, Cuiping,Huang, Yuan,Wang, Kai. 2025

[15]Dietary glycyrrhizin enhances reproductive performance by improving intestinal microbiota, liver lipid metabolism and ovarian senescence in aged breeder hens. Zhenwu Huang,Huchuan Liu,Guangju Wang,Huan Ge,Yanru Shi,Jinghai Feng,Chunmei Li,Minhong Zhang. 2025

[16]Whole Genome Sequencing and Extracellular Metabolite Profiling of Lactiplantibacillus plantarum FRT4: Insights into Probiotic Functionality. Yuyin Huang,Kun Meng,Guohua Liu,Zhimin Chen,Yunsheng Han,Peilong Yang,Rui Zhang,Hongying Cai. 2025

[17]Safety evaluation of daidzein in laying hens: Part I. Effects on laying performance, clinical blood parameters, and organs development. Shi, S. R.,Gu, H.,Chang, L. L.,Tong, H. B.,Zou, J. M.,Gu, H.,Wang, Z. Y.. 2013

[18]Safety evaluation of daidzein in laying hens: Part II. Effects on calcium-related metabolism. Gu, H.,Shi, S. R.,Chang, L. L.,Tong, H. B.,Zou, J. M.,Gu, H.,Wang, Z. Y.. 2013

[19]Influence of dietary taurine and housing density on oviduct function in laying hens. Dai, Bin,Zhang, Yuan-shu,Zheng, Liu-hai,Li, Shuang-jie,Miao, Jin-feng,Ma, Zi-li,Dou, Xin-hong,Gong, Jian-sen. 2015

[20]Ammonia and Greenhouse Gases Concentrations and Emissions of a Naturally Ventilated Laying Hen House in Northeast China. Dong, H.,Xin, H.,Xin, H..

作者其他论文 更多>>