数字农科院2.0

How ISWI-type chromatin remodelers drive pathogen virulence

文献类型: 外文期刊

作者: 唐广飞;;刘文德

关键词: tRNA Virulence

期刊名称: The Innovation

ISSN: 2666-6758

年卷期: 2025 年

页码:

收录情况: 不在遴选数据库范围(2023版)

摘要: ATP-dependent chromatin remodelers regulate eukaryotic chromatin structure; however, how imitation switch (ISWI)-type chromatin remodelers function in pathogens remains underexplored. Recent studies on Toxoplasma gondii and Fusarium graminearum have revealed how ISWI-type chromatin remodelers sustain virulence through similar mechanisms—nucleosome regulation, locus-specific targeting, and coupling to pathogenic pathways—offering novel antimicrobial targets.

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