数字农科院2.0

N6-Methyladenosine RNA Modification Regulates Maize Resistance to Maize Chlorotic Mottle Virus Infection

文献类型： 外文期刊

作者： Xia, Zihao;Zhang, Sijia;Guo, Huiyan;Gao, Xinran;Hao, Kaiqiang;Dong, Xue;Guo, Jinxiu;Li, Jian;Wang, Zhiping;An, Mengnan;Wu, Yuanhua;Zhou, Xueping

作者机构：

关键词： MeRIP-seq;RNA-seq;m(6)A modification;viral infection;maize;virus-induced genesilencing

期刊名称： JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

ISSN： 0021-8561

年卷期： 2024 年 72 卷 39 期

页码：

收录情况： SCIE（2024版） ; ; EI（2024版）

摘要： Maize chlorotic mottle virus (MCMV) is one of the main viruses causing significant losses in maize. N-6-methyladenosine (m(6)A) RNA modification has been proven to play important regulatory roles in plant development and stress response. In this study, we found that MCMV infection significantly up-regulated the m(6)A level in maize, and methylated RNA immunoprecipitation sequencing (MeRIP-seq) and RNA sequencing (RNA-seq) were performed to investigate the distribution of m(6)A modified peaks and gene expression patterns in MCMV-infected maize plants. The results showed that 1325 differentially methylated genes (DMGs) and 47 differentially methylated and expressed genes (DMEGs) were identified and analyzed. Moreover, the results of virus-induced gene silencing (VIGS) assays showed that ZmECT18 and ZmGST31 were required for MCMV infection, while silencing of ZmMTC, ZmSCI1 or ZmTIP1 significantly promoted MCMV infection in maize. Our findings provided novel insights into the regulatory roles of m(6)A modification in maize response to MCMV infection.

分类号：

  • 相关文献

[1]DissectingthemaizedirectandindirectdefenseresponseagainstAsianCornBorer. 汪海,李圣彦,查象敏,朱莉,黄大昉,郎志宏. 2015

[2]TheDifferentialTranscriptionNetworkbetweenEmbryoandEndospermintheEarlyDevelopingMaizeSeed. XiaoduoLu,DijunChen,DefengShu,ZhaoZhang,WeixuanWang,ChristianKlukas,Ling-lingChen,YunliuFan,MingChen,ChunyiZhang. 2015

[3]YTHDC1-Mediated m6A Modification of MAGI3 mRNA Regulates Proliferation and Differentiation of Myoblasts. Chen, Qian,He, Siqi,Xue, Xianglan,Zhang, Wen,Li, Hurong,He, Xiaohong,Pu, Yabin,Ma, Yuehui,Jiang, Lin,Zhao, Yanhong,Zhao, Qianjun. 2025

[4]Transcriptome Sequencing Identified Genes and Gene Ontologies Associated with Early Freezing Tolerance in Maize. Li, Zhao,Hu, Guanghui,Liu, Xiangfeng,Zhou, Yao,Zhang, Qian,Yang, Deguang,Zhang, Zhiwu,Li, Zhao,Hu, Guanghui,Zhang, Xu,Yuan, Xiaohui,Zhang, Zhiwu,Hu, Guanghui,Wang, Tianyu,Yuan, Xiaohui. 2016

[5]Overexpression of the maize GRF10, an endogenous truncated growth-regulating factor protein, leads to reduction in leaf size and plant height. Wu, Lei,Xue, Ming,Qian, Jianjun,He, Yan,Wang, Shoucai,Zhang, Dengfeng. 2014

[6]Comprehensive analysis of transcriptional data on seed germination of two maize inbred lines under low-temperature conditions. Yinchao Zhang,Peng Liu,Chaoying Zou,Zhong Chen,Guangsheng Yuan,Shibin Gao,Guangtang Pan,Yaou Shen,Langlang Ma. 2023

[7]Comparative transcriptome analysis of different nitrogen responses in low-nitrogen sensitive and tolerant maize genotypes. Qing guo DU,Juan YANG,Shah SYED MUHAMMAD SADIQ,Rong xin YANG,Jing juan YU,Wen xue LI. 2021

[8]Integration of GWAS, linkage analysis and transcriptome analysis to reveal the genetic basis of flowering time-related traits in maize. Xun Wu,Ying Liu,Xuefeng Lu,Liang Tu,Yuan Gao,Dong Wang,Shuang Guo,Yifei Xiao,Pingfang Xiao,Xiangyang Guo,Angui Wang,Pengfei Liu,Yunfang Zhu,Lin Chen,Zehui Chen. 2023

[9]Population-level gene expression can repeatedly link genes to functions in maize. Torres-Rodriguez, J. Vladimir,Li, Delin,Turkus, Jonathan,Newton, Linsey,Davis, Jensina,Lopez-Corona, Lina,Ali, Waqar,Sun, Guangchao,Mural, Ravi V.,Grzybowski, Marcin W.,Zamft, Bradley M.,Thompson, Addie M.,Schnable, James C.. 2024

[10]ZmBARK1 as a low-temperature tolerance gene in maize germination. Xu, Qingyu,Song, Yiying,Bao, Di,Meng, Lingzhi,Di, Hong,Zhang, Lin,Dong, Ling,Zeng, Xing,Zhang, Jiayue,Li, Chunxiang,Xing, Jiapeng,Zhang, Naifu,Li, Xin,Weng, Jianfeng,Wang, Zhenhua,Zhou, Yu. 2025

[11]Function Analysis of a Maize Endo-1,4-β-xylanase Gene ZmHSL in Response to High-Temperature Stress. Shengyan Pang,Hongyan Zheng,Jiankui Zhang,Xiaotian Ren,Xuefeng Zong,Junjie Zou,Lei Wang. 2024

[12]The transcriptome-wide N6-methyladenosine (m6A) map profiling reveals the regulatory role of m6A in the yak ovary. Shaoke Guo,Xingdong Wang,Mengli Cao,Xiaoyun Wu,Lin Xiong,Pengjia Bao,Min Chu,Chunnian Liang,Ping Yan,Jie Pei,Xian Guo. 2022

[13]Regulatory Role of N6-Methyladenosine in Longissimus Dorsi Development in Yak. Xiaoming Ma,Yongfu La,Pengjia Bao,Min Chu,Xian Guo,Xiaoyun Wu,Jie Pei,Xuezhi Ding,Chunnian Liang,Ping Yan. 2022

[14]Global N6-Methyladenosine Profiling Revealed the Tissue-Specific Epitranscriptomic Regulation of Rice Responses to Salt Stress. Yinxiao Wang,Fengping Du,Yingbo Li,Juan Wang,Xiuqin Zhao,Zhikang Li,Jianlong Xu,Wensheng Wang,Binying Fu. 2022

[15]Newcastle disease virus activates methylation-related enzymes to reprogram m6A methylation in infected cells. Weifeng Yuan,Yuechi Hou,Qingyi Wang,Ting Lv,Jinlian Ren,Lei Fan,Juncheng Cai,Bin Xiang,Qiuyan Lin,Ming Liao,Chan Ding,Libin Chen,Tao Ren. 2023

[16]Genome-wide identification of the m6A gene family and analysis of m6A methylome in alfalfa under drought stress. Xiang Meng,Dengxia Yi,Lin Ma,Xiaoran Ma,Kaiyun Xie,Xuemin Wang,Junbo Yang,Jun Tang. 2025

[17]Spread of recombinant Autographa californica nucleopolyhedrovirus in various tissues of silkworm Bombyx mori determined by real-time PCR. Zhang, Yi,Tian, Baozhong,Guo, Tingqing,Wang, Jianyang,Wei, Zhenguo,Lu, Changde,Zhang, Yi,Xia, Huanzhang,Tian, Baozhong,Wei, Zhenguo,Wang, Shengpeng.

[18]Microrna-34/449 Family And Viral Infections .. Lv, JL,Zhang, ZW,Pan, L,Zhang, YG. 2019

[19]The crosstalk between viral RNA- and DNA-sensing mechanisms. Chunmei Cai,Yan Dong Tang,Guocai Xu,Chunfu Zheng. 2021

[20]Histone deacetylase 6’s function in viral infection, innate immunity, and disease: latest advances. Min Qu,Huijun Zhang,Pengyuan Cheng,Ashenafi Kiros Wubshet,Xiangping Yin,Xiangwei Wang,Yuefeng Sun. 2023

作者其他论文 更多>>