数字农科院2.0

Whole transcriptome sequencing-based identification and functional prediction of salt-tolerant-related circular RNAs in ZM-4 (Malus zumi)

文献类型： 外文期刊

作者： Zhao Liu;Xiang Lu;Hanxin Guo;Wei Shang;Yuan Gao;Simiao Sun;Kun Wang;Wen Tian;Lin Wang;Zichen Li;Lianwen Li;Jianxin Niu;Dajiang Wang

作者机构：

关键词： circRNA;Malus zumi;Salt stress

期刊名称： International Journal of Biological Macromolecules

ISSN： 0141-8130

年卷期： 2025 年 306 卷

页码：

收录情况： SCIE（2025版） ; ; EI（2025版）

摘要： CircRNAs, are a class of covalently closed non-coding RNAs; they have been identified in many plants and play an important role in the response to abiotic stresses. However, little is known about the response of the circRNAs of salt-tolerant apple rootstock resources in response to salt stress. In this study, the leaves and roots of the salt-tolerant Malus resource, ZM-4, and the salt-sensitive rootstock M9T337, were used as test materials and were exposed to 75 mmol/L NaCl stress for 0 h and 24 h. A total of 2502 circRNAs were identified, and 218 and 242 circRNAs were uniquely expressed in M9T337 and ZM-4, respectively. Furthermore, it was shown that the up-regulated parental genes of the differentially expressed circRNAs were enriched in the metabolic pathways and the biosynthesis of secondary metabolites pathway in the leaves and roots of ZM-4 under salt stress, respectively. There were potential regulatory networks of ceRNA among 150 circRNAs, 139 miRNAs, and 397 mRNAs. Novel_circ_000845 and novel_circ_000266 could target and inhibit the expression of mdm-miR156 and up-regulate the expression of the salt-responsive gene SPL6. Six circRNAs, including novel_circ_000898 and novel_circ_001519, could target and inhibit the expression of mdm-miR10995 and up-regulate the expression of the salt-responsive gene COBL7. In conclusion, this study laid the foundation for the post-transcriptional molecular regulation mechanism of salt tolerance in apple rootstock resources.

分类号：

  • 相关文献

[1]Identification and analysis of miRNA-mRNA regulatory networks of ZM-4 (Malus zumi) in response to salt stress. Liu, Zhao,Gao, Yuan,Guo, Hanxin,Shang, Wei,Wang, Kun,Sun, Simiao,Wang, Lin,Tian, Wen,Li, Zichen,Sun, Yanming,Li, Lianwen,Niu, Jianxin,Wang, Dajiang. 2025

[2]Genome-wide characterization of salt-responsive mirnas, circrnas and associated cerna networks in tomatoes. Zhongyu Wang,Ning Li,Qinghui Yu,Huan Wang. 2021

[3]基于全转录组测序的绵羊胚胎不同发育阶段骨骼肌circRNA的分析与鉴定. 石田培,王欣悦,侯浩宾,赵志达,尚明玉,张莉. 2020

[4]牛体内囊胚全转录组模式解析. 王晶晶,张培培,郝海生,杜卫华,庞云渭,权国波,赵善江,邹惠影,朱化彬,赵学明. 2020

[5]Identification of Circular RNAs in the Ovaries of Hu Sheep and Local Fat-tailed Sheep during the Luteal Phase. Zhai, Zhenhan,Li, Jianhua,Zhang, Binglei,Wang, Mengyao,Ding, Hongxiang,Zhao, Lu,Wang, Saiqiao,Wei, Caihong,Wang, Yuqin. 2023

[6]Circular RNA ame_circ_2015 Function as microRNA Sponges in Regulating Egg-Laying of Honeybees (Apis mellifera). 陈晓,,安建东. 2023

[7]Systematic Investigation Of Circular Rnas I.n Ascosphaera Apis, A F ungal Pathogen Of Honeybee Larvae. Guo, R, Chen, DF, Chen, HZ, Fu, ZM, Xiong, CL, Hou, CS, Zheng, YZ, Guo, YL, Wang, HP, Du, Y, Diao, QY. 2018

[8]Identification And Characterization Of Circrnas O.f Two Pig Breeds A s A New Biomarker In Metabolism-Related Diseases. Li, A, Huang, WL, Zhang, XX, Xie, LL, Miao, XY. 2018

[9]Functional analysis of differentially expressed circular RNAs in sheep subcutaneous fat. Liu, Tian-yi,Feng, Hui,Yousuf, Salsabeel,Xie, Ling-li,Miao, Xiang-yang. 2023

[10]Sp1-mediated circrna circhipk2 regulates myogenesis by targeting ribosomal protein rpl7. Yan Junyu,Yang Yalan,Fan Xinhao,Tang Yijie,Tang Zhonglin. 2021

[11]Profiling and functional analysis of differentially expressed circular RNAs identified in foot-and-mouth disease virus infected PK-15 cells. Yang, JinKe,Yang, Bo,Wang, Yong,Zhang, Ting,Hao, Yu,Cui, HuiMei,Zhao, DengShuai,Yuan, XingGuo,Chen, XueHui,Shen, ChaoChao,Yan, WenQian,Zheng, HaiXue,Zhang, KeShan,Liu, Xiangtao. 2022

[12]Integrated analysis of the whole transcriptome of skeletal muscle reveals the ceRNA regulatory network related to the formation of muscle fibers in Tan sheep. Cui, Ran,Kang, Xiaolong,Liu, Yufang,Liu, Ximing,Chan, Shuheng,Wang, Yubei,Li, Zhen,Ling, Yao,Feng, Dengzhen,Li, Menghua,Lv, Fenghua,Fang, Meiying. 2022

[13]Expression Characteristics in Roots, Phloem, Leaves, Flowers and Fruits of Apple circRNA. Wang, Dajiang,Gao, Yuan,Sun, Simiao,Li, Lianwen,Wang, Kun. 2022

[14]Sp1-mediated circrna circhipk2 regulates myogenesis by targeting ribosomal protein rpl7. Yan Junyu,Yang Yalan,Fan Xinhao,Tang Yijie,Tang Zhonglin. 2021

[15]Profile Analysis Of Circrnas Induced B.y Porcine Endemic Diarrhea V irus Infection In Porcine Intestinal Epithelial Cells. Chen, JN,Wang, HW,Jin, L,Wang, LY,Huang, X,Chen, WW,Yan, MM,Liu, GL. 2019

[16]Trend Analysis Of The Role Of Circular Rna In Goat Skeletal Muscle Development. Ling, YH, Zheng, Q, Zhu, L, Xu, LN, Sui, MH, Zhang, YH, Liu, Y, Fang, FG, Ma, YH, Zhang, XR, Chu, MX. 2020

[17]circRNAome profiling reveals circFgfr2 regulates myogenesis and muscle regeneration via a feedback loop. Yan, Junyu,Yang, Yalan,Fan, Xinhao,Liang, Guoming,Wang, Zishuai,Li, Jiju,Wang, Liyuan,Chen, Yun,Adetula, Adeyinka Abiola,Tang, Yijie,Li, Kui,Wang, Dazhi,Tang, Zhonglin. 2022

[18]CircRNA Profiling Reveals an Abundant circBDP1 that Regulates Bovine Fat Development by Sponging miR-181b/miR-204 Targeting Sirt1/TRARG1. Zhang, Sihuan,Jiang, Enhui,Kang, Zihong,Bi, Yi,Liu, Hongfei,Xu, Han,Wang, Zhen,Lei, Chuzhao,Chen, Hong,Lan, Xianyong. 2022

[19]Supplementation with Milk-Derived Extracellular Vesicles Shapes the Gut Microbiota and Regulates the Transcriptomic Landscape in Experimental Colitis. Chunmei Du,Kun Wang,Yiguang Zhao,Xuemei Nan,Ruipeng Chen,Suyu Quan,Benhai Xiong. 2022

[20]Plant non-coding RNAs: The new frontier for the regulation of plant development and adaptation to stress. Wenxue Cao,Limei Yang,Mu Zhuang,Honghao Lv,Yong Wang,Yangyong Zhang,Jialei Ji. 2024

作者其他论文 更多>>