数字农科院2.0

UvKmt6-mediated H3K27 trimethylation is required for development, pathogenicity, and stress response in Ustilaginoidea virens

文献类型： 外文期刊

作者： Shuai Meng;;Zhiquan Liu;; Huanbin Shi;;Zhongling Wu;;Jiehua Qiu;;Hui Wen;; Fucheng Lin;;Zeng Tao;;Chaoxi Luo;;Yanjun Kou

关键词： Ustilaginoidea virens; virulence; PRC2; Kmt6; epigenetic regulation

期刊名称： Virulence

ISSN： 2150-5594

年卷期： 2021 年

页码：

收录情况： JCR（2021版）

摘要： Polycomb repressive complex 2 (PRC2) is responsible for the trimethylation of lysine 27 of histone H3 (H3K27me3)-mediated transcriptional silencing. At present, its biological roles in the devastating rice pathogenic fungus Ustilaginoidea virens remain unclear. In this study, we analyzed the function of a putative PRC2 catalytic subunit UvKmt6. The results showed that disruption of UvKMT6 resulted in reduced growth, conidiation and pathogenicity in U. virens. Furthermore, UvKmt6 is essential for establishment of H3K27me3 modification, which covers 321 genes in the genome. Deletion of UvKMT6 led to transcriptional derepression of 629 genes, 140 of which were occupied with H3K27me3 modification. Consistent with RNA-seq and ChIP-seq analysis, UvKmt6 was further confirmed to participate in the transcriptional repression of genes encoding effectors and genes associated with secondary metabolites production, such as PKSs, NRPSs and Cytochrome P450s. Notably, we found that UvKmt6 is involved in transcriptional repression of oxidative, osmotic, cell wall and nutrient starvation stresses response-related genes. From the perspective of gene expression and phenotype, in addition to the relatively conservative role in fungal development, virulence and production of secondary metabolites, we further reported that UvKmt6-mdediated H3K27me3 plays a critical role in the response to various stresses in U. virens.

分类号：

  • 相关文献

[1]采用AFLP技术分析稻曲病菌的遗传多样性Ⅰ:同一块稻田中稻曲病菌的遗传结构. 潘雅姣,樊金娟,付彬英,王洁,徐建龙,陈红漫,黎志康,周永力. 2006

[2]采用AFLP技术分析稻曲病菌的遗传多样性Ⅰ：同一块稻田中稻曲病菌的遗传结构. 潘雅姣,樊金娟,付彬英,王洁,徐建龙,陈红漫,黎志康,周永力. 2006

[3]The maternally expressed polycomb group gene OsEMF2a is essential for endosperm cellularization and imprinting in rice. Xiaojun Cheng,Meiyao Pan,Zhiguo E,Yong Zhou,Baixiao Niu,Chen Chen. 2021

[4]Dna Methylomes And Transcriptomes Analysis R.eveal Implication Of Host D na Methylation Machinery In Bmnpv Proliferation In Bombyx Mori. Zhang, Shaolun,Shang, Qi,Zhong, Jinbo,Guo, Xijie,Yin, Haotong,W, Ping,Hou, Qirui,Hou, Qirui,Guo, Xijie,Huang, Haoling,W, Ping,Hou, Qirui,W, Ping. 2019

[5]Corticosterone-Induced Lipogenesis Activation And Lipophagy I.nhibition In Chicken Liver A re Alleviated By Maternal Betaine Supplementation. Abobaker, Halima,Hou, Zhen,Abobaker, Halima,Zhao, Ruqian,Zong, Yibo,Zong, Yibo,Zhao, Ruqian,Hu, Yan,Hu, Yun,Omer, Nagmeldin A.,Sun, Qinwei,Hou, Zhen,Sun, Qinwei,Hu, Yun,Omer, Nagmeldin A.. 2018

[6]Genome-Wide Analysis Of The Distinct T.ypes Of Chromatin Interactions I n Arabidopsis Thaliana. Wang, Jingjing,Wang, Jingjing,Meng, Xianwen,Zhou, Yincong,Xue, Jitong,Xue, Jitong,Li, Xue,Chen, Ming,Chen, Ming,Chen, Hongjun,Li, Xue,Fan, Miao,Fan, Miao. 2017

[7]Mutations In The Rice Oschr4 G.ene, Encoding A Chd3 F amily Chromatin Remodeler, Induce Narrow And Rolled Leaves With Increased Cuticular Wax. Wang, Daofeng,Fang, Jingjing,Xiao, Langtao,Guo, Tingting,Yuan, Shoujiang,Zhao, Jinfeng,Li, Xueyong. 2019

[8]Epigenetic Regulation By The Menin P.athway. Feng, ZJ, Ma, J, Hua, XX. 2017

[9]Mutations In The Rice Oschr4 Gene, Encoding A Chd3 F amily Chromatin Remodeler, Induce Narrow And Rolled Leaves With Increased Cuticular Wax. Guo, TT, Wang, DF, Fang, JJ, Zhao, JF, Yuan, SJ, Xiao, LT, Li, XY. 2019

[10]Characterization of Shiga toxin-producing Escherichia coli isolated from Cattle and Sheep in Xinjiang province, China, using whole-genome sequencing. Liu Y., Li H., Chen X., Tong P., Zhang Y., Zhu M., Su Z., Yao G., Li G., Cai W.. 2022

[11]Main Ustilaginoidins and Their Distribution in Rice False Smut Balls. Meng, Jiajia,Sun, Weibo,Mao, Ziling,Xu, Dan,Wang, Xiaohan,Lu, Shiqiong,Lai, Daowan,Zhou, Ligang,Zhang, Guozhen,Liu, Yang. 2015

[12]The Contents of Ustiloxins A and B along with Their Distribution in Rice False Smut Balls. Wang, Xiaohan,Fu, Xiaoxiang,Lin, Fengke,Sun, Weibo,Meng, Jiajia,Wang, Ali,Lai, Daowan,Zhou, Ligang,Liu, Yang. 2016

[13]Detection of quantitative resistance loci associated with resistance to rice false smut ( Ustilaginoidea virens) using introgression lines. Zhou, Y. -L.,Xie, X. -W.,Zhang, F.,Zhu, L. -H.,Xu, J. -L.,Gao, Y. -M.,Li, Z. -K.,Zhou, Y. -L.,Zhang, F.,Xu, J. -L.,Gao, Y. -M.,Li, Z. -K.,Wang, S.,Liu, X. -Z.. 2014

[14]Bioactive Bis-naphtho-gamma-pyrones from Rice False Smut Pathogen Ustilaginoidea virens. Lu, Shiqiong,Sun, Weibo,Meng, Jiajia,Wang, Ali,Wang, Xiaohan,Tian, Jin,Fu, Xiaoxiang,Lai, Daowan,Zhou, Ligang,Dai, Jungui,Dai, Jungui,Liu, Yang.

[15]Preparative Separation of Main Ustilaginoidins from Rice False Smut Balls by High-Speed Counter-Current Chromatography. Sun, Weibo,Dong, Xuejiao,Xu, Dan,Meng, Jiajia,Fu, Xiaoxiang,Wang, Xiaohan,Lai, Daowan,Zhou, Ligang,Liu, Yang. 2016

[16]SUN-Family Protein UvSUN1 Regulates the Development and Virulence of Ustilaginoidea virens. Mina Yu,Junjie Yu,Huijuan Cao,Tianqiao Song,Xiayan Pan,Zhongqiang Qi,Yan Du,Rongsheng Zhang,Shiwen Huang,Wende Liu,Yongfeng Liu. 2021

[17]Insights into genomic evolution from the chromosomal and mitochondrial genomes of Ustilaginoidea virens. Zhang, Kang,Zhao, Zaixu,Zhang, Ziding,Li, Yuejiao,Li, Shaojie,Yao, Nan,Hsiang, Tom,Sun, Wenxian. 2021

[18]Ustilaginoidea Virens: A Fungus Infects R.ice Flower And Threats W orld Rice Production. Qiu, JH, Meng, S, Deng, YZ, Huang, SW, Kou, YJ. 2019

[19]UvWhi2 Is Required for Stress Response and Pathogenicity in Ustilaginoidea virens. Meng Shuai,Qiu Jiehua,Xiong Meng,Liu Zhiquan,Jagernath, Jane Sadhna,Lin Fucheng,Shi Huanbin,Kou Yanjun. 2022

[20]SUN-Family Protein UvSUN1 Regulates the Development and Virulence of Ustilaginoidea virens. Mina Yu,Junjie Yu,Huijuan Cao,Tianqiao Song,Xiayan Pan,Zhongqiang Qi,Yan Du,Rongsheng Zhang,Shiwen Huang,Wende Liu,Yongfeng Liu. 2021

作者其他论文 更多>>