数字农科院2.0

Effects of different ratio of sweet sorghum silage to corn silage diets on serum metabolome of lactating dairy cows

文献类型： 外文期刊

作者： Zhenping Hou;Xia Yu;Duanqin Wu

作者机构：

关键词： Corn Silage;Dairy Cow;Metabolomics;Serum;Sweet Sorghum Silage

期刊名称： Tropical Animal Health and Production

ISSN： 0049-4747

年卷期： 2025 年 57 卷 5 期

页码：

收录情况： SCIE（2025版）

摘要： The objective of this study was to investigate the impact of partially substituting whole corn silage (CS) with sweet sorghum silage (SS) on serum metabolites in dairy cows employing by Liquid chromatography-mass spectrometry (LC–MS). Thirty mid-lactation Holstein dairy cows (112 ± 24.04 days in milk) were divided into the control group (CON) received 40% CS and 0% SS, Group1 received 30% CS and 10% SS, while Group2 received 20% CS and 20% SS, respectively. Serum samples were collected on day 45 of the formal experiment and subjected to LC–MS analysis to detect metabolites. The results revealed that 29 different metabolites were obtained in both CON and Group1; however, 22 metabolites in Group1 showed up-regulation compared to those in CON including N-Methylhydantoin, Betaine, Isoleucine, etc. The levels of 7 metabolites, including L-Kynurenine, Nandrolone, and Testosterone propionate, were found to be down-regulated. Sixteen metabolites were detected in the serum of Group2 and CON dairy cows. Compared with CON, Group2 exhibited up-regulation of 13 metabolites such as Benzaldehyde, Linoleic acid, Phe-Glu. Conversely, three metabolites including Triglycerides (TG), Uric acid and 5-Hydroxyindole-3-acetic acid showed down-regulation. A total of 20 differential metabolites were identified in Group1 and Group2. Among these, 14 metabolites such as 2-Ethylacrylic acid, Succinic acid, and Glutamic acid were up-regulated while 6 metabolites like Pyridoxine, Phosphocholine, and Quinidine showed down-regulation. These differentially expressed metabolites are primarily associated with various pathways including Aminoacyl-tRNA, Arginine, Phenylalanine and tryptophan biosynthesis, Citrate cycle etc. In conclusion, substituting up to 50% of CS with SS had no negative effects on serum metabolites, indicating that SS can partially replace CS in the diets of high-producing lactating dairy cows without adding extra grain, when diets are fed for a short time under our feeding experimental conditions.

分类号：

  • 相关文献

[1]Effects of Dietary Natural Mycotoxins Exposure on Performance, Biochemical Parameters and Milk Small Molecule Metabolic Pathways of Lactating Cows. Wu, Xufang,Guo, Liya,Huang, Guoxin,Tang, Wenhao,Zhao, Shengguo,Wang, Jiaqi,Zhang, Yangdong. 2022

[2]Consumption of Supplementary Inulin Modulates Milk Microbiota and Metabolites in Dairy Cows with Subclinical Mastitis. Yue Wang,Xuemei Nan,Yiguang Zhao,Linshu Jiang,Hui Wang,Fan Zhang,Dengke Hua,Jun Liu,Junhu Yao,Liang Yang,Benhai Xiong. 2022

[3]Plasma metabolic profiling reveals that chromium yeast alleviates the negative effects of heat stress in mid-lactation dairy cows. Yeqianli Wo,Fengtao Ma,Qiang Shan,Duo Gao,Yuhang Jin,Peng Sun. 2023

[4]Dietary supplementation with inulin improves lactation performance and serum lipids by regulating the rumen microbiome and metabolome in dairy cows. Yue Wang,Xuemei Nan,Yiguang Zhao,Linshu Jiang,Hui Wang,Dengke Hua,Fan Zhang,Yapin Wang,Jun Liu,Junhu Yao,Benhai Xiong. 2021

[5]Effect of different dietary inclusion levels of whole plant green tomato (Physalis philadelphica) silage on nutrient intake and digestibility, and in vitro rumen fermentation kinetics in sheep. Lizbeth E. Robles-Jimenez,Alondra C. Narváez-López,Alfonso J. Chay-Canul,Aurora Sainz-Ramirez,Octavio A. Castelan-Ortega,Naifeng Zhang,Manuel Gonzalez-Ronquillo,Einar Vargas-Bello-Pérez. 2022

[6]Corn silage quality index: An index combining milk yield, silage nutritional and fermentation parameters. R.M.H. Tharangani,C. Yakun,L.S. Zhao,L. Ma,H.L. Liu,S.L. Su,L. Shan,Z.N. Yang,P.J. Kononoff,William P. Weiss,D.P. Bu. 2021

[7]Effect of Different Diet Formulas on Production Performance and Rumen Bacterial Diversity of Fattening Beef Cattle. Chen, Yingwu,Chen, Kai,Zhu, Xinqiang,Wang, Xiaoli,Leng, Feifan,Wang, Yonggang. 2025

[8]Seroprevalence of Toxoplasma gondii and Neospora caninum in Tarim Red Deer (Cervus elaphus yarkandensis) from Xinjiang Province, Northwest China. Meng, Q. L.,Qiao, J.,Wang, W. S.,Chen, C. F.,Zhang, Z. C.,Cai, K. J.,Tian, Z. Z.,Yang, L. H.,Cai, X. P.,Tian, G. F.. 2012

[9]Effects of heat stress on serum insulin, adipokines, AMP-activated protein kinase, and heat shock signal molecules in dairy cows. Min, Li,Shi, Bao-lu,Zheng, Nan,Wang, Jia-qi,Min, Li,Yang, Hong-jian,Cheng, Jian-bo. 2015

[10]The effect of implanting an antigen release device on lactoferrin concentration in serum and milk. Cheng, J. B.,Wang, J. Q.,Bu, D. P.,Liu, G. L.,Zhang, C. G.,Wei, H. Y.,Zhou, L. Y.,Wang, J. Z.,Iaschi, S. P. A.,Tay, K. G.,Zhang, C. G.,Wei, H. Y.,Zhou, L. Y.,Tay, K. G.. 2008

[11]Effects of non-phytate phosphorus levels and phytase sources on growth performance, serum biochemical and tibia parameters of broiler chickens. Jiang, Xian R.,Luo, Fa H.,Wu, Shu G.,Zhang, Hai J.,Yue, Hong Y.,Qi, Guang H.,Qu, Ming R.,Bontempo, Valentino. 2013

[12]Experimental infection with bovine ephemeral fever virus and analysis of its antibody response cattle. Zheng, F. Y.,Chen, Q. W.,Li, Z.,Gong, X. W.,Wang, J. D.,Yin, H..

[13]Graphene oxide-enabled tandem signal amplification for sensitive SPRi immunoassay in serum. Hu, Weihua,He, Guangli,Guo, Chun Xian,Lu, Zhisong,Li, Chang Ming,Hu, Weihua,He, Guangli,Guo, Chun Xian,Lu, Zhisong,Li, Chang Ming,Hu, Weihua,He, Guangli,Guo, Chun Xian,Lu, Zhisong,Li, Chang Ming,Chen, Tao,Selvaraj, Jonathan Nimal,Liu, Yang.

[14]Levels of Cu, Mn, Fe and Zn in Cow Serum and Cow Milk: Relationship with Trace Elements Contents and Chemical Composition in Milk. Wang, Hui,Liu, Yongming,Qi, Zhiming,Wang, Shengyi,Liu, Shixiang,Dong, Shuwei,Xia, Xinchao,Li, Shengkun,Liu, Zhiqi. 2014

[15]Determination of Cortisol in Human Serum Using Ultrasonic Extraction Coupled with Liquid Chromatography-Isotope Dilution Mass Spectrometry. Zhou Jian,Wang Min,Tang Xiao-Yan,Mao Xue-Fei,Dai Xin-Hua. 2013

[16]Identification of porcine serum proteins modified in response to HP-PRRSV HuN4 infection by two-dimensional differential gel electrophoresis. An, Tongqing,Gong, Daqing,Peng, Jinmei,Leng, Chaoliang,Yuan, Zhonghua,Tian, Zhijun,Yang, Yongqian,Li, Dengyun,Zhang, Deli,Tong, Guangzhi. 2012

[17]Expression Profiling Of Circulating Mirnas I.n Mouse Serum In R esponse To Echinococcus Multilocularis Infection. Guo, XL,Zheng, YD. 2017

[18]Expression and characterization of the serum proteome from yak induced into estrus by improved nutrition. Jianpeng Xie,Qudratullah Kalwar,Ping Yan,Xian Guo. 2022

[19]Altered miRNA Expression Profiles in the Serum of Beagle Dogs Experimentally Infected with Toxocara canis. Zheng W.-B.,Cai L.,Zou Y.,Gao W.-W.,Liu Q.,Zhu X.-Q.. 2023

[20]Metavirome Analysis Reveals a High Prevalence of Porcine Hemagglutination Encephalomyelitis Virus in Clinically Healthy Pigs in China. Weiyao Sun,Zhibin Shi,Pengfei Wang,Bingbing Zhao,Jiaqi Li,Xinyu Wei,Lili Wei,Jingfei Wang. 2023

作者其他论文 更多>>