Research Progress in Pharmacological Effects and Mechanisms of Angelica sinensis against Cardiovascular and Cerebrovascular Diseases
文献类型: 外文期刊
作者: Linlin Chen;Bei Fan;Fengzhong Wang;Yang Song;Xizhi Wang;Ying Meng;Yumin Chen;Qing Xia;Jing Sun
作者机构:
关键词: Angelica sinensis;cardiovascular and cerebrovascular diseases;medicinal and edible values;polysaccharide;volatile oil
期刊名称: Molecules (Basel, Switzerland)
ISSN: 1420-3049
年卷期: 2024 年 29 卷 9 期
页码:
收录情况: SCIE(2024版)
摘要: Angelica sinensis (Oliv.) Diels (A. sinensis) is a medicinal and edible values substance, which could promote blood circulation and enrich blood. It possesses rich chemical components and nutrients, which have significant therapeutic effects on cardiovascular and cerebrovascular diseases. It is commonly used for the prevention and treatment of cardiovascular and cerebrovascular diseases in the elderly, especially in improving ischemic damage to the heart and brain, protecting vascular cells, and regulating inflammatory reactions. This article reviews the main pharmacological effects and clinical research of A. sinensis on cardiovascular and cerebrovascular diseases in recent years, explores the effect of its chemical components on cardiovascular and cerebrovascular diseases by regulating the expression of functional proteins and inhibiting inflammation, anti-apoptosis, and antioxidant mechanisms. It provides a reference for further research on A. sinensis and the development of related drugs. It provides a new reference direction for the in-depth research and application of A. sinensis in the prevention, improvement, and treatment of cardiovascular and cerebrovascular diseases.
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