数字农科院2.0

Comparative Proteomics Analysis Of Human A.nd Ruminant Milk Serum R eveals Variation In Protection And Nutrition

文献类型： 外文期刊

作者： Lu, J; Zhang, SW; Liu, L; Pang, XY; Ma, CL; Jiang, SL; Lv, JP

作者机构：

关键词： Human milk; Ruminants milk; Proteomics; Immune proteins

期刊名称： FOOD CHEMISTRY

ISSN： 0308-8146

年卷期： 2018 年 261 卷

页码：

收录情况： JCR（2021版） ; EI（2021版）

摘要： In present study, 198, 169, 213 and 128 proteins were identified and quantified in human, cow, goat and yak milk serum respectively by using proteomics techniques. Large variations were observed between human and ruminant milk proteins. Human milk contained higher concentration of mucosal immune response, complement proteins and regulators. The concentration of bactericidal proteins were relatively higher in ruminants milk. Human milk exclusively expressed proteins important for delivery or utilization of nutrients. Peptidase inhibitors prevent the bioactive proteins/peptides in human milk from gastral-intestinal digestion. Protein composition among ruminants milk was similar but with variations. Goat milk contained high level of complement proteins but low level of corresponding regulators. In addition, the acute phase proteins were significantly higher in goat milk. Of note, osteopontin in yak milk was enriched, which could offer an alternative source for producing osteopontin and revealed possible nutritional value of yak milk.

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