数字农科院2.0

Association Between Tea Consumption And O.steoporosis A Meta-Analysis

文献类型： 外文期刊

作者： Li, Xinghui;Cui, Qiaoyun;Wang, Le;Zhang, Wenzheng;Sun, Kang;Lv, Qianru;Ma, Qingping;Sun, Kang

作者机构：

关键词： caffeine; green tea polyphenols; meta-analysis; osteoporosis; tea

期刊名称： MEDICINE

ISSN： 0025-7974

年卷期： 2017 年 96 卷 49 期

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摘要： Background: Previous reports have suggested a potential association of tea consumption with the risk of osteoporosis. As such association is controversial, we conducted a meta-analysis to assess the relationship between tea consumption and osteoporosis. Methods and Findings: We systematically searched PubMed, EMBASE and WanFang databases until March 30, 2016, using the keywords "tea and osteoporosis," without limits of language. Odds ratios (ORs) with 95% confidence intervals (95% CIs) were derived by using random-effects models throughout the analyses. We conducted the analysis of the statistical heterogeneity using Cochrane I-2. The funnel plot was used to speculate the publication bias, while the subgroup analysis and multiround elimination method were employed. Results: Our study was based on 17 journal articles, including 2 prospective cohort studies, 4 case-control studies, and 11 cross-sectional studies. In the present study, the total OR of osteoporosis for the highest versus the lowest categories of tea consumption was 0.62 (95% CI, 0.46-0.83), with significant heterogeneity among studies (I-2=94%, P <.01). There was, however, no publication bias of the meta-analysis about tea consumption and osteoporosis. Subgroup analysis showed that tea consumption could reduce the risk of osteoporosis in all examined subgroups. Conclusion: In the present study, it can be concluded from the results that tea consumption can reduce the risk of osteoporosis.

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