数字农科院2.0

Beneficial Effects Of Flaxseed Polysaccharides On Metabolic Syndrome Via Gut Microbiota In High-Fat Diet Fed Mice

文献类型： 外文期刊

作者： Yang, C; Xu, ZX; Deng, QC; Huang, QD; Wang, X; Huang, FH

作者机构：

关键词： Flaxseed Polysaccharides; Metabolic Syndrome; Gut Microbiota; Akkermansia

期刊名称： FOOD RESEARCH INTERNATIONAL

ISSN： 0963-9969

年卷期： 2020 年 131 卷

页码：

收录情况： JCR（2021版） ; EI（2021版）

摘要： Flaxseed (Linum usitatissimum L.) is known as healthy food for its anti-obesity and lipid modulating properties. However, the effects of flaxseed polysaccharide (FSP) on metabolic syndrome (MetS) and gut microbiota are still poorly understood. Here, we investigated the effects of FSP on lipid metabolism and gut microbiota in high-fat-diet-fed mice. FSP effectively reduced the serum fasting glucose, total triglyceride and total cholesterol levels. FSP consumption adipose accumulation impacted the gut microbiome at different taxonomic levels by increasing the proportions of beneficial Akkermansia and Bifidobacterium and decreasing the disease or obesity associated Oscillospira and Odoribacteraceae. These changes were highly correlated with the regulation of expression levels of lipid metabolism involved genes in the liver. The restoration of total SCFAs, especially propionate and butyrate might be an important strategy for mitigating HFD induced metabolic disorders. These findings suggest that FSP may use as a prebiotic for preventing MetS by modulating the gut microbiota.

分类号：

  • 相关文献

[1]High Oleic Acid Peanut Oil And Extra Virgin Olive Oil Supplementation Attenuate Metabolic Syndrome In Rats By Modulating The Gut Microbiota. Zhao, ZH, Shi, AM, Wang, Q, Zhou, JR. 2019

[2]Selenium Affects The Activity Of B.lack Tea In Preventing M etabolic Syndrome In High-Fat Diet-Fed Sprague-Dawley Rats. Gao, Y, Xu, YQ, Ruan, JY, Yin, JF. 2019

[3]Systemic Overexpression Of The 11 B.eta-Hsd1 Promotes Endoplasmic Reticulum S tress In Multiple Tissues And The Development Of Metabolic Syndrome In Mice. Li, CX, Xia, JH, Zhu, WJ, Xin, LL, An, CP, Yang, SL, Li, K. 2017

[4]Phenolic Acids Alleviate High-Fat And H.igh-Fructose Diet-Induced Metabolic Disorders I n Rats. Guo, XX, Wang, O, Wang, Y, Wang, K, Ji, BP, Zhou, F. 2017

[5]Gut flora-mediated metabolic health, the risk produced by dietary exposure to acetamiprid and tebuconazole. Liu Jingkun,Zhao Fangfang,Xu Yanyang,Qiu Jing,Qian Yongzhong. 2021

[6]Effect of fermented bee pollen on metabolic syndrome in high-fat diet-induced mice. Yan Sha,Wang Kai,Wang Xiaoying,Ou Aiqun,Wang Feiran,Wu Liming,Xue Xiaofeng. 2021

[7]Comparative Effect Of Black, Green, O.olong, And White Tea I ntake On Weight Gain And Bile Acid Metabolism. Xu, Hairong,Gaikwad, Nilesh W.,Ye, Jianhui,Sun, Lili. 2019

[8]Green And Black Tea Phenolics: B.ioavailability, Transformation By Colonic M icrobiota, And Modulation Of Colonic Microbiota. Liu, Zhibin,Bruins, Marieke Elisabeth,Liu, Zhibin,Liu, Zhibin,Ni, Li,Vincken, Jean-Paul. 2018

[9]Lactobacillus Reuteri I5007 Modulates Intestinal H.ost Defense Peptide Expression I n The Model Of Ipec-J2 Cells And Neonatal Piglets. Zeng, Xiangfang,Yu, Haitao,Hou, Chengli,Thacker, Philip A.,Zhang, Guolong,Jia, Hongmin,Hou, Chengli,Liu, Hongbin,Wang, Gang,Qiao, Shiyan. 2017

[10]Aspirin Eugenol Ester Regulates Cecal C.ontents Metabolomic Profile And M icrobiota In An Animal Model Of Hyperlipidemia. Ma, Ning,Jiao, Zeng-Hua,Li, Jian-Yong,Li, Shi-Hong,Liu, Xi-Wang,Ma, Ning,Qin, Zhe,Yang, Ya-Jun,Kong, Xiao-Jun. 2018

[11]Yeast Probiotics Shape The Gut M.icrobiome And Improve The H ealth Of Early-Weaned Piglets. Yang, Zhiqiang,Xu, Jinqiang,Wu, Zuowei,Li, Yuhui,Liang, Hongyan,Pu, Wanxia,Li, Chunhui. 2018

[12]Lotus Seed Oligosaccharides At Various Dosages With Prebiotic Activity Regulate Gut Microbiota And Relieve Constipation In Mice. Miao, Song,Zeng, Shaoxiao,Lu, Xu,Su, Han,Deng, Kaibo,Deng, Kaibo,Chen, Jinghao,Su, Han,Chen, Jinghao,Zheng, Baodong,Zeng, Shaoxiao,Deng, Kaibo,Miao, Song,Deng, Kaibo,Su, Han,Chen, Jinghao,Zheng, Baodong,Lu, Xu,Liu, Jiawen,Zeng, Shaoxiao,Zheng, Baodong,Lu, Xu,Zeng, Shaoxiao,Miao, Song,Lu, Xu,Lu, Xu,Zheng, Baodong,Deng, Kaibo. 2019

[13]Fuzhuan Brick Tea Attenuates High-Fat Diet-Induced Obesity And Associated Metabolic Disorders By Shaping Gut Microbiota. Luo, Yong,Huang, Jianan,Wu, Wenliang,Liu Zhonghua,Wu, Wenliang,Liu Zhonghua,Wen, Beibei,Liu, Dongmin,Zeng, Hongliang,Huang, Jianan,Liu, Dongmin. 2019

[14]Changes In Intestinal Microbiota Of Type 2 Diabetes In Mice In Response To Dietary Supplementation With Instant Tea Or Matcha. Zhang, Shi-kang,Huang, Mei-gui,Lv, Yang-jun,Liu, Jun,Zhang, Hai-hua,Zhu, Yue-jin,Pan, Jun-xian,Jiang, Yu-lan. 2020

[15]The Hepatotoxicity Of Palmitic Acid I.n Zebrafish Involves The I ntestinal Microbiota. Ding, QW, Zhang, Z, Ran, C, He, SX, Yang, YL, Du, ZY, Zhang, JX, Zhou, ZG. 2018

[16]Effects Of Schisandra Chinensis Polysaccharides O.n Rats With Antibiotic-Associated D iarrhea. Qi, YL, Chen, LX, Gao, K, Shao, ZJ, Huo, XH, Hua, M, Liu, SX, Sun, YS, Li, SS. 2019

[17]Effects Of Panax Ginseng Polysaccharides O.n The Gut Microbiota I n Mice With Antibiotic-Associated Diarrhea. Li, SS, Qi, YL, Chen, LX, Qu, D, Li, ZM, Gao, K, Chen, JB, Sun, YS. 2019

[18]Gut Microbiota Of Wild And Captive Alpine Musk Deer (Moschus Chrysogaster). Sun, YW, Sun, YJ, Shi, ZH, Liu, ZS, Zhao, C, Lu, TF, Gao, H, Zhu, F, Chen, R, Zhang, J, Pan, RL, Li, BG, Teng, LW, Guo, ST. 2020

[19]Comparative Analysis Of The Gut Microbiota Of The Blue Fox (Alopex Lagopus) And Raccoon Dog (Nyctereutes Procyonoides). Liu, HL, Li, ZP, Si, HZ, Zhong, W, Fan, ZY, Li, GY. 2020

[20]Synbiotic-Driven Improvement Of Metabolic Disturbances I.s Associated With Changes I n The Gut Microbiome In Diet-Induced Obese Mice. Walker, Alesia,Von Bergen, Martin,Liu, Yuwen,Schmitt-Kopplin, Philippe,Schmitt-Kopplin, Philippe,Schmitt-Kopplin, Philippe,Liu, Yuwen,Clavel, Thomas,Ke, Xinxin,Haange, Sven-Bastiaan,Cheung, Peter C. K.,Jehmlich, Nico,Clavel, Thomas,Lagkouvardos, Ilias,He, Xin. 2019

作者其他论文 更多>>