数字农科院2.0

Effect Of Titanium Dioxide Nanoparticles On The Resistance Of Silkworm To Cytoplasmic Polyhedrosis Virus Inbombyx Mori

文献类型： 外文期刊

作者： Zhao, GD; Zhang, X; Cheng, JL; Huang, X; Qian, HY; Li, G; Xu, AY

作者机构：

关键词： Bombyx Moricytoplasmic Polyhedrosis Virus; Titanium Dioxide Nanoparticles; Silkworm; Resistance-Related Genes

期刊名称： BIOLOGICAL TRACE ELEMENT RESEARCH

ISSN： 0163-4984

年卷期： 2020 年 196 卷 1 期

页码：

收录情况： JCR（2021版）

摘要： Bombyx moricytoplasmic polyhedrosis virus (BmCPV) is a serious disease harmful to silk industry, which is one of the major sources of financial support for farmers in many developing countries. So far, there is still no good way to prevent or treat this disease. In this study, titanium dioxide nanoparticles (TiO(2)NPs) were used to pretreat silkworm larvae, and good results were achieved in improving silkworm immunity and alleviating the damage of cytoplasmic polyhedrosis virus. The results showed that nano-titanium dioxide pretreatment could inhibit the proliferation of BmCPV in the midgut of silkworm, activate JAK/STAT and PI3K-AKT immune signaling pathways, and upregulate the expression of key immune genes, so as to improve the immunity of silkworm and enhance the resistance of silkworm to BmCPV.

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