数字农科院2.0

Identifying Candidate Genes For Hypoxia Adaptation Of Tibet Chicken Embryos By Selection Signature Analyses And Rna Sequencing

文献类型： 外文期刊

作者： Liu, XY; Wang, XC; Liu, J; Wang, XY; Bao, HG

作者机构：

关键词： Tibet Chicken; Hypoxia Adaptation; Signatures Of Selection; Rna Sequencing

期刊名称： GENES

ISSN：

年卷期： 2020 年 11 卷 7 期

页码：

收录情况： JCR（2021版）

摘要： The Tibet chicken (Gallus gallus) lives on the Qinghai-Tibet Plateau and adapts to the hypoxic environment very well. The objectives of this study was to obtain candidate genes associated with hypoxia adaptation in the Tibet chicken embryos. In the present study, we used the fixation index (Fst) and cross population extended haplotype homozygosity (XPEHH) statistical methods to detect signatures of positive selection of the Tibet chicken, and analyzed the RNA sequencing data from the embryonic liver and heart with HISAT, StringTie and Ballgown for differentially expressed genes between the Tibet chicken and White leghorn (Gallus gallus, a kind of lowland chicken) embryos hatched under hypoxia condition. Genes which were screened out by both selection signature analysis and RNA sequencing analysis could be regarded as candidate genes for hypoxia adaptation of chicken embryos. We screened out 1772 genes by XPEHH and 601 genes by Fst, and obtained 384 and 353 differentially expressed genes in embryonic liver and heart, respectively. Among these genes, 89 genes were considered as candidate genes for hypoxia adaptation in chicken embryos. ARNT, AHR, GSTK1 and FGFR1 could be considered the most important candidate genes. Our findings provide references to elucidate the molecular mechanism of hypoxia adaptation in Tibet chicken embryos.

分类号：

  • 相关文献

[1]Genome-Wide Scanning Reveals Genetic Diversity A.nd Signatures Of Selection I n Chinese Indigenous Cattle Breeds. Xu, L, Zhang, WG, Shen, HX, Zhang, Y, Zhao, YM, Jia, YT, Gao, X, Zhu, B, Xu, LY, Zhang, LP, Gao, HJ, Li, JY, Chen, Y. 2018

[2]Epas1 Gain-Of-Function Mutation Contributes To High-Altitude Adaptation In Tibetan Horses. Liu, XX, Zhang, YL, Li, YF, Pan, JF, Wang, DD, Chen, WH, Zheng, ZQ, He, XH, Zhao, QJ, Pu, YB, Guan, WJ, Han, JL, Orlando, L, Ma, YH, Jiang, L. 2019

[3]Population Genetic Variations Of The M.atrix Metalloproteinases-3 Gene Revealed H ypoxia Adaptation In Domesticated Yaks (Bos Grunniens). Ding, XZ, Yang, C, Bao, PJ, Wu, XY, Pei, J, Yan, P, Guo, X. 2019

[4]Complementary Rna-Sequencing Based Transcriptomics And I.traq Proteomics Reveal The M echanism Of The Alleviation Of Quinclorac Stress By Salicylic Acid In Oryza Sativa Ssp Japonica. Zhou, Weijun,Yang, Chong,Wang, Jian,Mao, Bizeng,Long, Meijuan,Li, Lan,Jin, Xiaoli,Islam, Faisal,Ali, Basharat,Ali, Basharat. 2017

[5]Characterization Of Circular Rnas In C.hinese Buffalo (Bubalus Bubalis) A dipose Tissue: A Focus On Circular Rnas Involved In Fat Deposition. Wei, Xuefeng,Huang, Jieping,Li, Fen,Ma, Yun,Zheng, Qiuzhi,Huang, Jieping,Lei, Chuzhao,Wang, Shuzhe,Ma, Yun,Shang, Jianghua,Zhao, Jinhui. 2019

[6]1-Mcp Treatment Affects Peach Fruit A.roma Metabolism As Revealed B y Transcriptomics And Metabolite Analyses. Han, Shuai,Cai, Hongfang,Jiang, Li,Yu, Zhifang,Yu, Mingliang,Ma, Ruijuan. 2019

[7]P8 Nuclear Receptor Responds To A.caricides Exposure And Regulates T ranscription Of P450 Enzyme In The Two-Spotted Spider Mite, Tetranychus Urticae. Hu Jia,Lu Wencai,Hu Yuan,Liu Peiling,Xu Zhifeng,Xu Zhifeng,He Lin,Hu Jia,Liu Peiling,He Lin,Hu Yuan. 2019

[8]Transcriptomic Studies Reveal A Key M.etabolic Pathway Contributing To A Well-Maintained Photosynthetic System Under Drought Stress In Foxtail Millet (Setaria Italica L.). Wen, Xiaojie,Shi, Weiping,Guo, Pingyi,Yao, Jiayan,Sun, Qian,Cheng, Jingye,Xiang, Peng,Wang, Jixiang,Cheng, Jingye,Hou, Liyuan,Shi, Guanyan,Guo, Jie,Yuan, Xiangyang,Dong, Shuqi. 2018

[9]Genome-Wide Analysis And Identification Of T.he Low Potassium Stress R esponsive Gene Simyb3 In Foxtail Millet (Setariaitalica L.). Xu, Zhaoshi,Chen, Xueyan,Ma, Youzhi,Song, Jianming,Hu, Liqin,Cheng, Dungong,Chen, Ming,Cao, Xinyou,Li, Haosheng,Li, Liancheng,Liu, Cheng,Liu, Jianjun,Zhao, Zhendong,Zhou, Yongbin,Liu, Aifeng,Zhang, Rongzhi. 2019

[10]Comparative Transcriptome Reveals Circadian And H.ormonal Control Of Adventitious R ooting In Mulberry Hardwood Cuttings. Cheng, Jialing,Cheng, Jialing,Liu, Li,Shen, Qiudi,Shang, Chunqiong,Shen, Qiudi,Liu, Li,Du, Wei,Cao, Xu,Cao, Xu,Shang, Chunqiong. 2018

[11]An Integrated Analysis Of Qtl M.apping And Rna Sequencing P rovides Further Insights And Promising Candidates For Pod Number Variation In Rapeseed (Brassica Napus L.). Yang, Yuhua,Wang, Xinfa,Zhan, Jiepeng,Ye, Jiang,Wang, Hanzhong,Liu, Guihua,Chen, Bo,Shi, Jiaqin,Luo, Meizhong. 2017

[12]Detecting Novel Loci Underlying Rice B.last Resistance By Integrating A Genome-Wide Association Study And Rna Sequencing. Wang, Caihong,Wang, Shan,Wang, Yiping,Lu, Qing,Lu, Qing,Niu, Xiaojun,Yu, Hanyong,Yuan, Xiaoping,Zhang, Mengchen,Feng, Yue,Wei, Xinghua,Xu, Qun,Yang, Yaolong. 2019

[13]Involvement Of Salicylic Acid In A.nthracnose Infection In Tea P lants Revealed By Transcriptome Profiling. Shi, Yun-Long,Sheng, Yue-Yue,Liang, Yue-Rong,Ye, Jian-Hui,Yang, Rui,Wang, Kai-Rong,Li, Da,Guo, Xiao-Yuan,Cai, Zhuo-Yu,Zheng, Xin-Qiang,Li, Xu-Min,Li, Qing-Sheng,Lu, Jian-Liang,Zhang, Long-Jie. 2019

[14]Maternal Transcription Profiles At Different Stages For The Development Of Early Embryo In Buffalo. Chen, Fumei,Lu, Yangqing,Pang, Chunying,Pang, Chunying,Liang, Xianwei,Pu, Liping,Zhang, Pengfei,Zhang, Ming,Xu, Zhuangzhuang,Deng, Tingxian,Fu, Qiang,Hou, Zhen,Deng, Tingxian,Liang, Xianwei. 2020

[15]Genome-wide identification and comparative analysis of drought related genes in roots of two maize inbred lines with contrasting drought tolerance by RNA sequencing. Tang Huai-jun,Xie Xiao-qing,Zhang Deng-feng,Liu Cheng,Song Yan-chun,Shi Yun-su,Li Yu,Wang Tian-yu,Hao Lu-yang,Liu Xu-yang,Li Yong-xiang,Li Chun-hui,Zhang Xiao-jing,Sun Bao-cheng. 2020

[16]Transcriptome Of Porcine Alveolar Macrophages A.ctivated By Interferon-Gamma And L ipopolysaccharide. Liu, Q, Zhang, YL, Hu, W, Hu, SP, Zhang, Z, Cai, XH, He, XJ. 2018

[17]Genome-Wide Screening And Analysis Of I.mprinted Genes In Rapeseed ( Brassica Napus L.) Endosperm. Liu, J, Li, J, Liu, HF, Fan, SH, Singh, S, Zhou, XR, Hu, ZY, Wang, HZ, Hua, W. 2018

[18]Identification Of Genes Alternatively Spliced I.n Developing Maize Endosperm. Xie, S, Zhang, X, Zhou, Z, Li, X, Huang, Y, Zhang, J, Weng, J. 2018

[19]Mutation Status Coupled With Rna-Sequencing D.ata Can Efficiently Identify I mportant Non-Significantly Mutated Genes Serving As Diagnostic Biomarkers Of Endometrial Cancer. Liu, KQ, He, L, Liu, ZC, Xu, JM, Liu, Y, Kuang, QF, Wen, ZN, Li, ML. 2017

[20]Comparative transcriptome in large-scale human and cattle populations. Yao Y., Liu S., Xia C., Gao Y., Pan Z., Canela-Xandri O., Khamseh A., Rawlik K., Wang S., Li B., Zhang Y., Pairo-Castineira E., D’Mellow K., Li X., Yan Z., Li C.-J., Yu Y., Zhang S., Ma L., Cole J.B., Ross P.J., Zhou H., Haley C., Liu G.E., Fang L., Tenesa A.. 2022

作者其他论文 更多>>