数字农科院2.0

SERS spectroscopy of kaempferol and galangin under the interaction of human serum albumin with adsorbed silver nanoparticles

文献类型： 外文期刊

作者： Zhang, Wei;Bai, Xueyuan;Zhao, Daqing;Zhao, Yu;Zhang, Wei;Wang, Yingping;Zhao, Bing

作者机构：

关键词： Galangin;Human serum albumin;Interaction;Kaempferol;Surface enhanced Raman scattering (SERS)

期刊名称： SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

ISSN：

年卷期：

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收录情况： SCI

摘要： Raman and surface-enhanced Raman scattering (SERS) spectroscopy were employed to probe the interaction of the flavonol drugs, kaempferol and galangin, with human serum albumin (HSA). SERS spectra of both flavonol derivatives were obtained from a colloidal silver surface in physiological condition, based on the high performance of the enhanced substrate, the most enhanced modes of kaempferol and galangin were those with certain motions perpendicular to the metal surface. The SERS spectra were allowed to predict similar orientation geometry for both of the drugs on the colloidal surface with minor difference. In addition, both flavonols-HSA complexes were prepared in different concentration ratios and the orientated differences between kaempferol and galangin were investigated by SERS.

分类号： O657.3

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