数字农科院2.0

Three new cyclopentenone derivatives from Actinoalloteichus nanshanensis NEAU 119

文献类型： 外文期刊

作者： Zhang, Ji;Liu, Chong-Xi;Xiang, Wen-Sheng;Qian, Ping-Ting;Wang, Ji-Dong;Xiang, Wen-Sheng

作者机构：

关键词： Actinoalloteichus nanshanensis NEAU 119;Cyclopentenone;Cytotoxic activity

期刊名称： JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH

ISSN：

年卷期：

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收录情况： SCI

摘要： Three new cyclopentenone derivatives (1-3) were isolated from the rare actinomycete Actinoalloteichus nanshanensis NEAU 119. Their structures were elucidated by extensive spectroscopic analysis. Compound 1 showed moderate cytotoxic activity against human lung adenocarcinoma cell line A549, human leukemia cell line K562, and human renal carcinoma cell line ACHN with an IC50 of 14.67, 11.87, and 23.36 μg ml-1, respectively.

分类号： R9

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