数字农科院2.0

A new subgenotype 2.1d isolates of classical swine fever virus in China, 2014

文献类型： 外文期刊

作者： Zhang, Hongliang;Feng, Liping;Chen, Jiazeng;Liu, Chunxiao;Bai, Yun;Ye, Chao;Peng, Jinmei;An, Tongqing;Cai, Xuehui;Tian, Zhijun;Leng, Chaoliang;Zhai, Hongyue;Kan, Yunchao;Tong, Guangzhi

作者机构：

关键词： Classical swine fever virus;New subgenotype;E2

期刊名称： INFECTION GENETICS AND EVOLUTION

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年卷期：

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收录情况： SCI

摘要： The lapinized attenuated vaccine against classical swine fever (CSF) has been used in China for over half a century and has generally prevented large-scale outbreaks in recent years. However, since late 2014, a large number of new cases of CSF were detected in many immunized pig farms in China. Several of these CSV viruses were isolated and characterized. Phylogenetic and genomic sequence analyses indicate that these new isolates, as well as some reference isolates, form a new subgenotype named 2.1d, and share several consistent molecular characteristics. Since these new isolates emerged in disparate geographic regions within 5 months, this suggests that these isolates may be widespread. Given that current vaccines do not appear to provide effective protection against this new subgenotype, further investigation of these strains is urgently needed. (C) 2015 Elsevier B.V. All rights reserved.

分类号： R1

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