数字农科院2.0

A narrative review on MicroRNA's role in diagnosis and therapy of equine endometritis

文献类型： 外文期刊

作者： Sana Asif;Muhammad Wasif Gulzar

作者机构：

关键词： Bacterial endotoxins;Cytokines;Endometritis;Infertility;MicroRNAs

期刊名称： Journal of Reproductive Immunology

ISSN： 0165-0378

年卷期： 2025 年 169 卷

页码：

收录情况： SCIE（2025版）

摘要： Endometritis is a significant cause of infertility in mare. Some infectious agents disrupt the endometrium's innate immune system, resulting in a prolonged systemic inflammatory response that circulates via the blood or cellular degeneration, which ultimately leads to endometritis from bacterial endotoxins. Numerous biological processes use various small, non-coding RNA molecules called MicroRNAs. MicroRNAs (miRNAs) regulate gene expression after transcription by blocking transcription and translation. This manuscript examines patho-morphological discoveries in equine endometritis, the expression and effects of eca-miR-17, eca-miR-223, eca-miR-200a, eca-miR-155, and eca-miR-205, and the therapeutic function of miRNA in endometritis. MiRNAs play a crucial role in controlling inflammatory disorders by modulating cytokine signaling pathways. This review emphasizes the demand for cutting-edge genetic technologies and the development of novel pharmaceutical preparations to improve our understanding of the genes encoding by these miRNAs. It also focuses on the efficacy of miRNAs for control, early diagnosis, and prevention of endometritis.

分类号：

  • 相关文献

[1]感染日本血吸虫小鼠循环血miRNAs变化分析. 朱丽慧,刀金威,杜晓利,李浩,陆珂,刘金明,程国锋. 2015

[2]microRNAs在植物发育调控中的功能研究进展. 王迪,傅彬英,黎志康,张立军. 2006

[3]MicroRNAs 与脂类代谢. 南雪梅,王加启,陈海燕,胡菡. 2013

[4]MicroRNAs与脂类代谢. 南雪梅,王加启,陈海燕,胡菡. 2013

[5]顶复门原虫诱导宿主microRNAs变化的研究进展. 范艺凡,周东辉,徐民俊,李成琳,朱兴全,蒋文灿. 2012

[6]MicroRNA通路在多房棘球蚴多功能干细胞neoblasts中的调控作用. 郭小腊,郑亚东. 2015

[7]弓形虫感染食蟹猴的实验研究. 李海龙,袁子国,张秀香,宋慧群,周东辉,徐民俊,林瑞庆,宁章勇,黄思扬,朱兴全. 2011

[8]油菜和拟南芥菌核病抗性相关基因的功能研究. 任秋红,黄军艳,田保明,刘胜毅. 2009

[9]Vaginal microbiota are associated with in vitro fertilization during female infertility. Wang, Tao,Li, Penghao,Bai, Xue,Tian, Shilin,Yang, Maosen,Leng, Dong,Kui, Hua,Zhang, Sujuan,Yan, Xiaomiao,Zheng, Qu,Luo, Pulin,He, Changming,Jia, Yan,Wu, Zhoulin,Qiu, Huimin,Li, Jing,Wan, Feng,Ali, Muhammad A.,Mao, Rurong,Liu, Yong-Xin,Li, Diyan. 2024

[10]Expression Pattern of Cathelicidins in Dairy Cows During Endometritis and Role of Bovine Endometrial Epithelial Cells in Production of Cathelicidins. Yajuan Li,Xiaoyu Ma,Jie Yang,Xiaohu Wu,Zuoting Yan,Baoxiang He. 2021

[11]MicroRNA miR-24-3p Mediates the Negative Regulation of Lipopolysaccharide-Induced Endometrial Inflammatory Response by Targeting TNF Receptor-Associated Factor 6 (TRAF6). Ayodele Olaolu Oladejo,Yajuan Li,Bereket Habte Imam,Xiaoyu Ma,Wenxiang Shen,Xiaohu Wu,Wei Jiang,Jie Yang,Yanan Lv,Xuezhi Ding,Shengyi Wang,Zuoting Yan. 2022

[12]Andrograpanin mitigates lipopolysaccharides induced endometritis via TLR4/NF-κB pathway. Baoyi Yin,Talha Umar,Xiaofei Ma,Yu Chen,Zaima Umar,Saqib Umer,Ganzhen Deng. 2022

[13]miR-424-5p overexpression inhibits LPS-stimulated inflammatory response in bovine endometrial epithelial cells by targeting IRAK2. Talha Umar,Xiaofei Ma,Baoyi Yin,Saqib Umer,Arshad Zahoor,Muhammad Akhtar,Zaima Umar,Aftab Shaukat,Ganzhen Deng. 2022

[14]Inhibition of Neutrophil Extracellular Traps Formation by Cl-Amidine Alleviates Lipopolysaccharide-Induced Endometritis and Uterine Tissue Damage. Wenxiang Shen,Ayodele Olaolu Oladejo,Xiaoyu Ma,Wei Jiang,Juanshan Zheng,Bereket Habte Imam,Shengyi Wang,Xiaohu Wu,Xuezhi Ding,Baohua Ma,Zuoting Yan. 2022

[15]Neutrophil Extracellular Traps Mediate Bovine Endometrial Epithelial Cell Pyroptosis in Dairy Cows with Endometritis. Wenxiang Shen,Xiaoyu Ma,Dan Shao,Xiaohu Wu,Shengyi Wang,Juanshan Zheng,Yanan Lv,Xuezhi Ding,Baohua Ma,Zuoting Yan. 2022

[16]Prevalence and molecular characterization of extended-spectrum β–lactamase—producing Escherichia coli isolates from dairy cattle with endometritis in Gansu Province, China. Zhang K.,Feng H.,Zhang J.,Guo Z.,Yan Z.,Wang G.,Wang X.,Wang L.,Li J.. 2024

[17]Lineage-Specific Evolved Micrornas Regulating Nb-Lrr D.efense Genes In Triticeae. Zhang, Rongzhi,Li, Yulian,Li, Wei,Zhang, Shujuan,Zhang, Shujuan,Gao, Jie,Zheng, Yongsheng,Li, Wei,Li, Genying,Gao, Jie,Li, Yulian,Song, Guoqi,Li, Genying,Zheng, Yongsheng,Li, Genying,Li, Wei,Gao, Jie,Song, Guoqi,Hao, Weiwei,Zhang, Rongzhi,Zhang, Shujuan,Song, Guoqi,Zhang, Rongzhi,Zheng, Yongsheng,Li, Yulian. 2019

[18]Microrna Expression Profile In Raw264.7 M.acrophage Cells Exposed To E chinococcus Multilocularis Metacestodes. Guo, Xiaola,Guo, Xiaola,Zheng, Yadong,Zheng, Yadong. 2018

[19]IDENTIFICATION OF miRNAs IN SWEET POTATO BY SOLEXA SEQUENCING. Bian, X.,Ma, P.,Jia, Z.,Guo, X.,Xie, Y.,E, Z..

[20]Distinctive microRNA profiles in the salivary glands of Haemaphysalis longicornis related to tick blood-feeding. Zhou, Jinlin,Zhou, Yongzhi,Cao, Jie,Zhang, Houshuang,Yu, Yingfang. 2013

作者其他论文 更多>>