数字农科院2.0

Peptidoglycan Recognition Protein S2 From Silkworm Integument: Characterization, Microbe-Induced Expression, and Involvement in the Immune-Deficiency Pathway

文献类型: 外文期刊

作者: Yang, Jie;Wang, Xiaonan;Wu, Jinmei;Tang, Shunming;Shen, Zhongyuan;Wu, Jinmei

作者机构:

关键词: Bombyx mori;innate immunity;peptidoglycan recognition protein;RNA interference

期刊名称: JOURNAL OF INSECT SCIENCE

ISSN: 1536-2442

年卷期: 2015 年 15 卷

页码:

收录情况: SCI

摘要: Peptidoglycan recognition protein (PGRP) binds specifically to peptidoglycan and plays an important role as a pattern recognition receptor in the innate immunity of insects. The cDNA of a short-type PGRP, an open reading frame of 588 bp encoding a polypeptide of 196 amino acids, was cloned from Bombyx mori. A phylogenetic tree was constructed, and the results showed that BmPGRP-S2 was most similar to Drosophila melanogaster PGRP (DmPGRP-SA). The induced expression profile of BmPGRP-S2 in healthy Escherichia coli-and Bacillus subtilis-challenged B. mori was measured using semiquantitative reverse transcriptase polymerase chain reaction analysis. The expression of BmPGRP-S2 was upregulated at 24 h by E. coli and Ba. subtilis challenge. In addition, in the integument of B. mori, RNAi knockdown of BmPGRP-S2 caused an obvious reduction in the transcription expression of the transcription factor Relish and in antibacterial effector genes Attacin, Gloverin, and Moricin. The results indicated that BmPGRP-S2 participates in the signal transduction pathway of B. mori.

分类号:

  • 相关文献

[1]Cloning and expression analysis of a peptidoglycan recognition protein in silkworm related to virus infection. Gao, Kun,Qian, He-ying,Qin, Guang-xing,Hou, Cheng-xiang,Guo, Xi-jie,Gao, Kun,Qian, He-ying,Qin, Guang-xing,Hou, Cheng-xiang,Guo, Xi-jie,Gao, Kun,Deng, Xiang-yuan.

[2]Differential and spatial regulation of the prophenoloxidase (proPO) and proPO-activating enzyme in cuticular melanization and innate immunity in Bombyx mori pupae. Zou, Feng Ming,Lee, Kwang Sik,Kim, Bo Yeon,Jin, Byung Rae,Zou, Feng Ming,Kim, Hong Ja,Gui, Zhong Zheng,Zhang, Guo Zheng,Guo, Xijie. 2015

[3]Newcastle disease virus-like particles induce DC maturation through TLR4/NF-kappa B pathway and facilitate DC migration by CCR7-CCL19/CCL21 axis. Qian, Jing,Xu, Xiaohong,Ding, Jiaxin,Yin, Renfu,Xue, Cong,Cong, Yanlong,Ding, Zhuang,Sun, Yixue,Wang, Jianzhong,Wang, Chunfeng,Ding, Chan,Yu, Shengqing,Liu, Xiufan,Hu, Shunlin.

[4]Transcript Profiling of Toll-Like Receptor mRNAs in Selected Tissues of Mink (Neovison vison). Tong, Mingwei,Yi, Li,Cheng, Yuening,Zhang, Miao,Cao, Zhigang,Wang, Jianke,Zhao, Hang,Lin, Peng,Cheng, Shipeng,Yang, Yong.

[5]Two myeloid differentiation factor 88 (MyD88) isoforms identified in ducks. Cheng, Yuqiang,Wang, Hengan,Yan, Yaxian,Sun, Jianhe,Ding, Chan.

[6]Molecular cloning and functional characterization of a novel isoform of chicken myeloid differentiation factor 88 (MyD88). Qiu, Yafeng,Shen, Yang,Li, Xiangdong,Ding, Chan,Ma, Zhiyong.

[7]A secreted cystatin from the tick Haemaphysalis longicornis and its distinct expression patterns in relation to innate immunity. Zhou, Jinlin,Ueda, Mami,Umemiya, Rika,Battsetseg, Badgar,Boldbaatar, Damdinsuren,Xuan, Xuenan,Fujisaki, Kozo.

[8]Icariin induces the expression of toll-like receptor 9 in Ana-1 murine macrophages. Li, Li,Miao, Jianhua,Xu, Yongli,Peng, Lina,Qiu, Yafeng,Gao, Xiaoqi,Shi, Zixue,Shao, Donghua,Ma, Zhiyong,Zhou, Ying.

[9]Molecular cloning of Peking duck Toll-like receptor 3 (duTLR3) gene and its responses to reovirus infection. Song, Kaijie,Li, Chuanfeng,Chen, Zongyan,Ding, Chan,Liu, Guangqing,Zhang, Miaotao,Song, Kaijie. 2015

[10]Regulatory effects of dietary L-Arg supplementation on the innate immunity and antioxidant ability in broiler chickens. Hu Ya-di,Tan Jian-zhuang,Qi Ji,Zhang Hong-fu. 2016

[11]Goose RIG-I functions in innate immunity against Newcastle disease virus infections. Sun, Yingjie,Ding, Na,Yu, Shengqing,Meng, Chunhun,Chen, Hongjun,Qiu, Xusheng,Zhang, Shilei,Yu, Yang,Zhan, Yuan,Ding, Chan,Ding, Siyu Serena.

[12]Glycyrrhetinic acid extracted from Glycyrrhiza uralensis Fisch induces the expression of Toll-like receptor 4 in Ana-1 murine macrophages. Li, Li,Miao, Jian-Hua,Xu, Yong-Li,Peng, Li-Na,Qiu, Ya-Feng,Gao, Xiao-Qi,Shi, Zi-Xue,Shao, Dong-Hua,Wei, Jian-Chao,Ma, Zhi-Yong,Zhou, Ying. 2011

[13]Recent Progress in Understanding PAMP- and Effector-Triggered Immunity against the Rice Blast Fungus Magnaporthe oryzae. Liu, Jinling,Ning, Yuese,Ding, Bo,Wang, Xuli,Wang, Guo-Liang,Liu, Jinling,Wang, Zhilong,Liu, Jinling,Wang, Zhilong,Wang, Guo-Liang. 2013

[14]The VP3 structural protein of foot-and-mouth disease virus inhibits the IFN-beta signaling pathway. Li, Dan,Yang, Wenping,Yang, Fan,Liu, Huanan,Zhu, Zixiang,Lian, Kaiqi,Liu, Xiangtao,Zheng, Haixue,Lei, Caoqi,Li, Shu,Shu, Hongbing.

[15]The role of effectors and host immunity in plant-necrotrophic fungal interactions. Jiang, Nan,Liu, Wende,Wang, Guo-Liang,Jiang, Nan,Liu, Jinling,Jiang, Nan,Liu, Jinling,Wang, Guo-Liang.

[16]The Tug-Of-War Between Plants And V.iruses: Great Progress And M any Remaining Questions. Cheng, Xiaofei,Zhou, Xueping,Zhou, Xueping,Wu, Xiaoyun,Valli, Adrian,Antonio Garcia, Juan. 2019

[17]The Innate Immunity Of Guinea P.igs Against Highly Pathogenic A vian Influenza Virus Infection. Zhang, K, Xu, WW, Zhang, ZW, Liu, J, Li, J, Sun, LJ, Sun, WY, Jiao, PR, Sang, XY, Ren, ZG, Yu, ZJ, Li, YG, Feng, N, Wang, TC, Wang, HL, Yang, ST, Zhao, YK, Zhang, XM, Wilker, PR, Liu, WJ, Liao, M, Chen, HL, Gao, YW, Xia, XZ. 2017

[18]Innate Sensing Of Influenza A V.irus Hemagglutinin Glycoproteins By T he Host Endoplasmic Reticulum (Er) Stress Pathway Triggers A Potent Antiviral Response Via Er-Associated Protein Degradation. Frabutt, DA, Bin Wang, B, Riaz, S, Schwartz, RC, Zheng, YH. 2018

[19]USP7 Promotes deubiquitination and stabilization of MyD88 to enhance immune responses. Zhang N.,Wang F.,Zhang G.,Zhang Q.,Liu Y.,Wang Q.,Elsharkawy M.S.,Zheng M.,Wen J.,Zhao G.,Li Q.. 2022

[20]A transcriptomic atlas of Aedes aegypti reveals detailed functional organization of major body parts and gut regional specializations in sugar-fed and blood-fed adult females. Hixson, Bretta,Bing, Xiao-Li,Yang, Xiaowei,Bonfini, Alessandro,Nagy, Peter,Buchon, Nicolas. 2022

作者其他论文 更多>>