数字农科院2.0

Combined toxicity of butachlor, atrazine and lambda-cyhalothrin on the earthworm Eisenia fetida by combination index (CI)-isobologram method

文献类型： 外文期刊

作者： Chen, Chen;Qian, Yongzhong;Wang, Yanhua;Zhao, Xueping;Wang, Qiang;Wang, Yanhua;Zhao, Xueping;Wang, Qiang

作者机构：

关键词： Butachlor;Atrazine;lambda-Cyhalothrin;Eisenia fetida;Acute mixture toxicity;Combination index method

期刊名称： CHEMOSPHERE

ISSN： 0045-6535

年卷期： 2014 年 112 卷

页码：

收录情况： SCI

摘要： Pesticides in the environment do not appear singly and usually occur as complex mixtures and their combined effect may exhibit toxicity to organisms. The individual and combined toxicities of two herbicides, atrazine and butachlor and an insecticide lambda-cyhalothrin have been examined to the earthworm Eisenia fetida, as a non-target terrestrial organism, in artificial soil and filter paper tests. The order of toxicity for the individual pesticides was ranked as atrazine > lambda-cyhalothrin > butachlor in both tests. We applied the combination index (CI)-isobologram method which is widely used to study chemical interactions to determine the nature of toxicological interactions of the pesticides and it allows computerized quantitation of synergism, additive effect and antagonism. For most cases in artificial soil test, synergism was observed in majority of the mixtures except for the combination of butachlor plus lambda-cyhalothrin. This particular combination displayed opposite interaction in filter paper test. The CI method was compared with the classical models of Concentration Addition (CA) and Independent Action (IA) and we found that CI method could accurately predict the combined toxicity and can serve as a useful tool in ecotoxicological risk assessment. (C) 2014 Elsevier Ltd. All rights reserved.

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