数字农科院2.0

Metavirome of 31 tick species provides a compendium of 1,801 RNA virus genomes

文献类型： 外文期刊

作者： Xue Bing Ni;Xiao Ming Cui;Jin Yue Liu;Run Ze Ye;Yu Qian Wu;Jia Fu Jiang;Yi Sun;Qian Wang;Marcus Ho Hin Shum;Qiao Cheng Chang;Lin Zhao;Xiao Hu Han;Ke Ma;Shi Jing Shen;Ming Zhu Zhang;Wen Bin Guo;Jin Guo Zhu;Lin Zhan;Liang Jing Li;Shu Jun

作者机构：

期刊名称： Nature Microbiology

ISSN： 2058-5276

年卷期： 2023 年 8 卷 1 期

页码：

收录情况： SCIE（2023版）

摘要： The increasing prevalence and expanding distribution of tick-borne viruses globally have raised health concerns, but the full repertoire of the tick virome has not been assessed. We sequenced the meta-transcriptomes of 31 different tick species in the Ixodidae and Argasidae families from across mainland China, and identified 724 RNA viruses with distinctive virome compositions among genera. A total of 1,801 assembled and complete or nearly complete viral genomes revealed an extensive diversity of genome architectures of tick-associated viruses, highlighting ticks as a reservoir of RNA viruses. We examined the phylogenies of different virus families to investigate virome evolution and found that the most diverse tick-associated viruses are positive-strand RNA virus families that demonstrate more ancient divergence than other arboviruses. Tick-specific viruses are often associated with only a few tick species, whereas virus clades that can infect vertebrates are found in a wider range of tick species. We hypothesize that tick viruses can exhibit both ‘specialist’ and ‘generalist’ evolutionary trends. We hope that our virome dataset will enable much-needed research on vertebrate-pathogenic tick-associated viruses.

分类号：

  • 相关文献
作者其他论文 更多>>