数字农科院2.0

Shining insights: Deciphering the biogenic synthesis of Ajuga bracteosa-mediated gold nanoparticles with advanced microscopy techniques

文献类型： 外文期刊

作者： Afreen, Afshan;Hameed, Hajra;Tariq, Muhammad;Sharif, Muhammad Shakeeb;Ahmed, Rashid;Waheed, Abdul;Kousar, Momina Bint;Akram, Zeeshan

作者机构：

关键词： advanced microscopy;Ajuga bracteosa;characterization;gold nanoparticles

期刊名称： MICROSCOPY RESEARCH AND TECHNIQUE

ISSN： 1059-910X

年卷期： 2024 年

页码：

收录情况： SCIE（2024版） ; ; EI（2024版）

摘要： In this study, gold nanoparticles (AuNPs) were bioreduced from Ajuga bracteosa, a medicinal herb known for its therapeutic properties against various diseases. Different fractions of the plant extract were used, including the methanolic fraction (ABMF), the n-hexane fraction (ABHF), the chloroform fraction (ABCF), and the aqueous extract for AuNPs synthesis. The characterization of AuNPs was performed using UV-Vis spectrophotometry, FT-IR, XRD, EDX, and TEM. UV-Vis spectroscopy confirmed the formation of AuNPs, with peaks observed at 555 nm. FT-IR analysis indicated strong capping of phytochemicals on the surface of AuNPs, which was supported by higher total phenolic contents (TPC) and total flavonoid contents (TFC) in AuNPs. XRD results showed high crystallinity and a smaller size distribution of AuNPs. TEM analysis revealed the spherical shape of AuNPs, with an average size of 29 +/- 10 nm. The biologically synthesized AuNPs exhibited superior antibacterial, antioxidant, and cytotoxic activities compared to the plant extract fractions. The presence of active biomolecules in A. bracteosa, such as neoclerodan flavonol glycosides, diterpenoids, phytoecdysone, and iridoid glycosides, contributed to the enhanced biological activities of AuNPs. Overall, this research highlights the potential of A. bracteosa-derived AuNPs for various biomedical applications due to their remarkable therapeutic properties and effective capping by phytochemicals.

分类号：

  • 相关文献

[1]Biofabrication of Fe3O4 Nanoparticles from Spirogyra hyalina and Ajuga bracteosa and Their Antibacterial Applications. Muhammad Shakeeb Sharif,Hajra Hameed,Abdul Waheed,Muhammad Tariq,Afshan Afreen,Asif Kamal,Eman A. Mahmoud,Hosam O. Elansary,Saddam Saqib,Wajid Zaman. 2023

[2]Characterization of microRNAs from sheep (Ovis aries) using computational and experimental analyses. Sheng, Xihui,Wei, Caihong,Liu, Tao,Zhang, Li,Du, Lixin,Sheng, Xihui,Song, Xuemei,Yu, Yan,Niu, Lili,Li, Shangang,Li, Hongbin.

[3]Gold Nanoparticle-Aptamer Based Colorimetric Biosensing Assays. Liu Jin-chuan,Lu Zhen-zhen,Chen Ai-liang. 2014

[4]Dual Reaction-Based Multimodal Assay for Dopamine with High Sensitivity and Selectivity Using Functionalized Gold Nanoparticles. Zeng, Zhanghua,Cui, Bo,Wang, Yan,Sun, Changjiao,Zhao, Xiang,Cui, Haixin. 2015

[5]Sensitive detection of multiple mycotoxins by SPRi with gold nanoparticles as signal amplification tags. Hu, Weihua,Chen, Hongming,Zhang, Hilanhuan,He, Guangli,Li, Xin,Li, Chang Ming,Hu, Weihua,Chen, Hongming,Zhang, Hilanhuan,He, Guangli,Li, Xin,Li, Chang Ming,Hu, Weihua,Chen, Hongming,Zhang, Hilanhuan,He, Guangli,Li, Xin,Li, Chang Ming,Hu, Weihua,Zhang, Xiaoxing,Liu, Yang.

[6]Ultrasmall Graphene Oxide Supported Gold Nanoparticles as Adjuvants Improve Humoral and Cellular Immunity in Mice. Cao, Yuhua,Ma, Yufei,Zhang, Mengxin,Wang, Haiming,Tu, Xiaolong,Shen, He,Dai, Jianwu,Zhang, Zhijun,Cao, Yuhua,Zhang, Mengxin,Tu, Xiaolong,Shen, He,Wang, Haiming,Guo, Huichen.

[7]Enzymatic reporting of peste des petits ruminants virus genes ligating two specific probes on nanoparticles. Tao, Chunai,Li, Gang,Wang, Yong,Huang, Huaxin,Tao, Chunai,Li, Gang,Wang, Yong,Huang, Huaxin,Wang, Yong.

[8]Ultrasensitive and quantitative gold nanoparticle-based immunochromatographic assay for detection of ochratoxin A in agro-products. Majdinasab, Marjan,Li, Peiwu,Zhang, Qi,Li, Xin,Tang, Xiaoqian,Majdinasab, Marjan,Sheikh-Zeinoddin, Mahmoud,Soleimanian-Zad, Sabihe,Li, Peiwu,Zhang, Qi,Li, Xin,Tang, Xiaoqian,Li, Peiwu,Li, Peiwu.

[9]The Applications of Gold Nanoparticle-Initialed Chemiluminescence in Biomedical Detection. Liu, Zezhong,Zhao, Furong,Gao, Shandian,Shao, Junjun,Chang, Huiyun. 2016

[10]Sensitive immunoassay for the beta-agonist ractopamine based on glassy carbon electrode modified with gold nanoparticles and multi-walled carbon nanotubes in a film of poly-arginine. Wang, Peilong,Su, Xiaoou,Zhou, Ying,Zhao, Hong,He, Yujian,He, Yujian. 2014

[11]A sandwich dipstick assay for ATP detection based on split aptamer fragments. Zhu, Chao,Zhao, Yan,Yan, Mengmeng,Huang, Yafei,Yan, Jiao,Bai, Wenhui,Chen, Ailiang,Zhu, Chao,Zhao, Yan,Yan, Mengmeng,Huang, Yafei,Yan, Jiao,Bai, Wenhui,Chen, Ailiang,Huang, Yafei,Yan, Jiao.

[12]Colorimetric detection of ractopamine and salbutamol using gold nanoparticles functionalized with melamine as a probe. Wang, Peilong,Su, Xiaoou,Zhou, Ying,Zhao, Hong,He, Yujian,He, Yujian.

[13]High sensitive rapid visual detection of sulfadimethoxine by label-free aptasensor. Chen, Ailiang,Jiang, Xiaoling,Zhang, Weiwei,Chen, Gang,Zhao, Yan,Tunio, Tarique Muhammad,Liu, Jinchuan,Lv, Zhenzhen,Yang, Shuming,Chen, Ailiang,Jiang, Xiaoling,Zhang, Weiwei,Chen, Gang,Zhao, Yan,Tunio, Tarique Muhammad,Liu, Jinchuan,Yang, Shuming,Lv, Zhenzhen,Li, Cheng.

[14]Label free electrochemical aptasensor for ultrasensitive detection of ractopamine. Wang, Peilong,Wang, Ruiguo,Su, Xiaoou,Yang, Fei,Shi, Lei,Zhou, Ying,He, Yujian,Yao, Dongsheng.

[15]Detection and differentiation of influenza viruses with glycan-functionalized gold nanoparticles. Zheng, Longtang,Lv, Xun,Bi, Yuhai,Zhang, Zhenxing,Wang, Pengfei,Liu, Ruichen,Jiang, Jingwen,Cong, Haolong,Liu, Wenjun,Gao, George F.,Li, Xuebing,Li, Xuebing,Zheng, Longtang,Zhang, Zhenxing,Wang, Pengfei,Jiang, Jingwen,Li, Xuebing,Wei, Jinhua,Du, Yuguang,Wu, Peixing,Liang, Jingnan,Cheng, Wenwen,Jiang, Xingyu,Cao, Hongzhi,Bi, Yuhai,Liu, Wenjun,Gao, George F.,Li, Xuebing,Cheng, Wenwen.

[16]Enhancing The Sensitivity Of The Bio-Barcode Immunoassay For Triazophos Detection Based On Nanoparticles And Droplet Digital Polymerase Chain Reaction. Cui, XY, Jin, MJ, Zhang, C, Du, PF, Chen, G, Qin, GX, Jiang, ZJ, Zhang, YD, Li, MJ, Liao, Y, Wang, YS, Cao, Z, Yang, FY, Abd El-Aty, AM, Wang, J. 2019

[17]A highly sensitive bio-barcode immunoassay for multi-residue detection of organophosphate pesticides based on fluorescence anti-quenching. Xu L.,Zhang X.,Abd El-Aty A.M.,Wang Y.,Cao Z.,Jia H.,Salvador J.-P.,Hacimuftuoglu A.,Cui X.,Zhang Y.,Wang K.,She Y.,Jin F.,Zheng L.,Pujia B.,Wang J.,Jin M.,Hammock B.D.. 2022

[18]DNA-Directed Seeded Synthesis of Gold Nanoparticles without Changing DNA Sequence. Lu, Chang,Zandieh, Mohamad,Zheng, Jinkai,Liu, Juewen. 2022

[19]Enhanced Bio-Barcode Immunoassay Using Droplet Digital PCR for Multiplex Detection of Organophosphate Pesticides. Xueyan Cui,A. M. Abd El-Aty,Chan Zhang,Lingyuan Xu,Haijin Liu,Huiyan Jia,Yuanshang Wang,Zhen Cao,J. Pablo Salvador,Yongxin She,Fen Jin,Jing Wang,Maojun Jin,Bruce D. Hammock. 2021

[20]Electrochemical Biosensor Using Nitrogen-Doped Graphene/Au Nanoparticles/DNAzyme for Ca2+ Determination. Zhixue Yu,Hui Wang,Yiguang Zhao,Fan Zhang,Xiangfang Tang,Benhai Xiong. 2022

作者其他论文 更多>>