Enhancing 1O2 Production with Biomimetic Pt Catalysts through Electronic Structure Modification
文献类型: 外文期刊
作者: Liu; Zhenjiang; Qin; Jie; Chen; Hailong; Xue; Yuan; Wang; Zedong; Shen; Bingqing; Li; Ming; Guo; Yanguo; Li; Longhua; Li; Yuanbo; Zhu; Chengzhou
作者机构:
关键词: biomimetic catalysts; hydrogen peroxide; electronic structure modification; singlet oxygen; bacterial inhibition
期刊名称: NANO LETTERS
ISSN: 1530-6984
年卷期: 2025 年
页码:
收录情况: SCIE(2025版) ; ; EI(2025版)
摘要: Singlet oxygen (1O2) is an excellent reactive oxygen species in the biomedical disinfection field; however, efficient and selective generation of 1O2 remains challenging. Herein, we design bioinspired Pt@UiO-66-X catalysts (X = -NH2, -H, -Br), with Pt nanoparticles as active centers and metal-organic framework (MOF) nanocavities as biomimetic binding pockets, to form a tailored electronic microenvironment for enhancing 1O2 generation. The results demonstrate that the electron-withdrawing functionalized Pt@UiO-66-Br can significantly improve the production efficiency of 1O2, which is 1.5 and 2.5 times higher than those of Pt@UiO-66 and Pt@UiO-66-NH2, respectively. Ab initio calculations reveal that electron-withdrawing functional groups can reduce the local electron density of Pt, thereby leading to a decrease in antibonding-orbital occupancy in Pt-Oads and subsequently facilitating the formation of *OO. Importantly, the Pt@UiO-66-Br catalyst shows good antibacterial properties both in vitro and in vivo. This work provides a promising prospect for the rational design of high-performance biomimetic catalysts for antibacterial application.
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