数字农科院2.0

Seroprevalence and Associated Risk Factors of Peste des Petits Ruminants Virus in Small Ruminants of Punjab, Pakistan

文献类型： 外文期刊

作者： Alvi, Mughees Aizaz;Yan, Hong-Bin;Kharl, Rai Bahadur;Ali, Aliza;Zeeshan, Muhammad;Jia, Wan-Zhong;Ren, Shanhui;Meng, Xuelian;Zhu, Xueliang;Ghafoor, Muzafar;Saqib, Muhammad;Li, Li;Dou, Yongxi

作者机构：

关键词： competitive ELISA;epidemiological modeling;goat;PPRV;sheep

期刊名称： TRANSBOUNDARY AND EMERGING DISEASES

ISSN： 1865-1674

年卷期： 2026 年 2026 卷 1 期

页码：

收录情况： SCIE（2025版）

摘要： Peste des petits ruminants (PPR) is a highly contagious viral disease prevalent in sheep and goats, and causes significant economic losses. The study was conducted in 2024 in Punjab Province, Pakistan, to estimate the seroprevalence of the PPR virus (PPRV) and to analyze animal-level risk factors in unvaccinated small ruminants. Over a 12-month period, multistage random sampling provided 722 serum samples of sheep and goats aged 6 months or older, collected across six districts. The anti-PPRV antibodies were detected using competitive enzyme-linked immunosorbent assay (cELISA), and species, age, sex, breed, parity, lactation status, pregnancy status, body condition score (BCS), and reproductive history were analyzed using univariable and multivariable logistic regression analyses. The overall seroprevalence rate was 79.77%, but significantly higher in goats (90.27%) than in sheep (68.75% and p < 0.0001). The results demonstrated district wise disparity, with variation in seroprevalence between districts: 52.05% (Okara) and 100% (Nankana). An increased likelihood of seropositivity was found to be associated with male sex, some breeds (Makhi Cheeni and Beetal), certain species-district interactions, and age-sex interactions. These data confirm the high endemicity of PPRV in Punjab and justify the targeted vaccination and surveillance in high-risk areas and among susceptible animal populations.

分类号：

  • 相关文献

[1]Genetic variation and population structure of Taenia multiceps (Coenurus cerebralis) based on mitochondrial cox1 gene: A comprehensive global analysis. Shahbaz Ul Haq,Muhammad Abdullah Malik,Ayed Alshammari,Abu Bakar Yameen,Majed H. Wakid,Mughees Aizaz Alvi,Abdulbaset Mohammad Kabli,Muhammad Saqib,Warda Qamar,Muhammad Sohail Sajid,Fenfei Gao,Li Li,Bao Quan Fu,Hong Bin Yan,Wan Zhong Jia. 2024

[2]赖氨酸对绵羊GHR基因表达的影响(英文). 李建升,程胜利,韩向敏,冯瑞林,岳耀敬,杨博辉,刘建斌. 2009

[3]基于ssRNA-seq研究差异基因、NATs对藏羊高原低氧适应的调控. 岳耀敬,冯瑞林,王天翔,郭婷婷,李桂英,孙晓萍,刘建斌,李文辉,牛春娥,郭健,李范文,杨博辉. 2015

[4]小反刍兽疫病毒P蛋白的表达、纯化及抗体的制备及初步应用. 翟军军,窦永喜,张海瑞,毛立,蒙学莲,王秋霞,骆学农,才学鹏. 2010

[5]纳米金标记核酸探针检测小反刍兽疫病毒核酸的研究. 陶春爱,邱文英,李刚,田康乐. 2012

[6]Identification of amino-acid residues in the V protein of peste des petits ruminants essential for interference and suppression of STAT-mediated interferon signaling. Ma, Xusheng,Yang, Xing,Zhang, Zhidong,Dou, Yongxi,Luo, Xuenong,Su, Junhong,Zhu, Qiyun,Cai, Xuepeng,Nian, Xiaofeng,Zhang, Xuehu.

[7]Development Of Real-Time And Lateral F.low Strip Reverse Transcription R ecombinase Polymerase Amplification Assays For Rapid Detection Of Peste Des Petits Ruminants Virus. Yang, Y,Qin, XD,Song, YM,Zhang, W,Hu, GW,Dou, YX,Li, YM,Zhang, ZD. 2017

[8]Analysis and sequence alignment of peste des petits ruminants virus chinasx2020. Lingxia Li,Jinyan Wu,Xiaoan Cao,Jijun He,Xiangtao Liu,Youjun Shang. 2021

[9]Peste des Petits Ruminants Virus Upregulates STING to Activate ATF6-Mediated Autophagy. Zhang, Rui,Lin, Hanrui,You, Qing,Zhang, Zhixiong,Bai, Ling,Chen, Fei,Zhu, Xueliang,Zhang, Zhidong,Li, Yanmin. 2022

[10]Interaction with the Receptor SLAM and Baculovirus Surface Display of Peste des petits ruminants Virus Hemagglutinin. Zhao, Lulu,Zhang, Zhidong,Meng, Xuelian,Du, Mengtan,Liu, Xingjian,Zhang, Zhifang,Li, Yinu. 2020

[11]Peste Des Petits Ruminants Virus N Protein Is a Critical Proinflammation Factor That Promotes MyD88 and NLRP3 Complex Assembly. Li, Lingxia,Yang, Wenping,Ma, Xiaoxia,Wu, Jinyan,Qin, Xiaodong,Cao, Xiaoan,Zhou, Jianhua,Jin, Li,He, Jijun,Zheng, Haixue,Liu, Xiangtao,Li, Dan,Shang, Youjun. 2022

[12]Research Progress on Emerging Viral Pathogens of Small Ruminants in China during the Last Decade. Li Mao,Wenliang Li,Fei Hao,Leilei Yang,Jizong Li,Min Sun,Wenwen Zhang,Maojun Liu,Xuenong Luo,Zilong Cheng. 2022

[13]Peste Des Petits Ruminants Virus N.ucleocapsid Protein Inhibits Beta I nterferon Production By Interacting With Irf3 To Block Its Activation. Zhu, ZX,Li, PF,Yang, F,Cao, WJ,Zhang, XL,Dang, W,Ma, XS,Tian, H,Zhang, KS,Zhang, MT,Xue, QH,Liu, XT,Zheng, HX. 2019

[14]Peste Des Petits Ruminants Virus Nucleocapsid Protein Interacts with Protein Kinase R-Activating Protein and Induces Stress Granules To Promote Viral Replication. Chen, Shuying,Yang, Fan,Cao, Weijun,Zhang, Xiangle,Liu, Huisheng,Zhang, Keshan,Liu, Xiangtao,Wang, Jingyu,Zheng, Haixue,Zhu, Zixiang. 2023

[15]The inhibitory and anti-inflammatory effects of TMP269 on peste des petits ruminants virus replication. Miaomiao Li,Yang Wang,Qunhua Ke,Min Qu,Xuelian Meng,Yuefeng Sun. 2025

[16]Development of a competitive ELISA method based on VLPs detecting the antibodies of serotype A FMDV. Yun Zhang,Rui Wang,Manyuan Bai,Xuefei Wang,Hu Dong,Jiajun Li,Suyu Mu,Haisheng Miao,Jianling Song,Shiqi Sun,Huichen Guo. 2022

[17]Development and validation of a competitive ELISA based on virus-like particles of serotype Senecavirus A to detect serum antibodies. Manyuan Bai,Rui Wang,Shiqi Sun,Yun Zhang,Hu Dong,Huichen Guo. 2021

[18]A new nanobody-enzyme fusion protein–linked immunoassay for detecting antibodies against influenza A virus in different species. Pinpin Ji,Kun Wang,Lu Zhang,Zhenda Yan,Min Kong,Xuwen Sun,Qiang Zhang,Ning Zhou,Baoyuan Liu,En Min Zhou,Yani Sun,Xinjie Wang,Qin Zhao. 2022

[19]Development and Evaluation of a Competitive Enzyme-Linked Immunosorbent Assay Based on Swine Monoclonal Antibodies for Detecting Neutralizing Antibodies against Senecavirus A. Ma, Xueqing,Huang, Jiaxin,Li, Kun,Ding, Kailu,Fu, Yuanfang,Zhang, Jing,Zhao, Zhixun,Li, Pinghua,Bai, Xingwen,Li, Dong,Liu, Xia,Zeng, Qiaoying,Liu, Zaixin,Sun, Pu,Lu, Zengjun. 2023

[20]Development and Validation of a Competitive ELISA Based on Bovine Monoclonal Antibodies for the Detection of Neutralizing Antibodies against Foot-and-Mouth Disease Virus Serotype A. Yimei Cao,Kun Li,Xiangchuan Xing,Guoqiang Zhu,Yuanfang Fu,Huifang Bao,Xingwen Bai,Pu Sun,Pinghua Li,Jing Zhang,Xueqing Ma,Jian Wang,Zhixun Zhao,Dong Li,Zaixin Liu,Zengjun Lu. 2022

作者其他论文 更多>>