数字农科院2.0

Rapid immunoassays for the detection of quinoxalines and their metabolites residues in animal-derived foods: A review

文献类型： 外文期刊

作者： Liangni Qin;Jiaxu Xiao;Hongfei Yang;Jixiang Liang;Long Li;Shixiang Wu;Dapeng Peng

作者机构：

关键词： （0-1-3）Animal-derived foods;Antibody;Hapten design;Immunoassays;Quinoxalines metabolites;Residue detection

期刊名称： Food Chemistry

ISSN： 0308-8146

年卷期： 2024 年 443 卷

页码：

收录情况： SCIE（2024版） ; ; EI（2024版）

摘要： Quinoxalines are a class of veterinary drugs with antibacterial and growth-promoting functions. They are often widely used to treat and prevent animal diseases and are illegally used as animal growth promoters to increase economic benefits. Quinoxalines could be easily metabolized in animals to various residue markers and remain in animal-derived foods, which would pose a serious threat to human health. Consequently, it is necessary to detect the residues of quinoxalines and their metabolites. This article reviewed and evaluated immunoassays for quinoxalines and their metabolites in animal-derived foods, mainly including enzyme-linked immunosorbent assays, fluorescence immunosorbent assays, immunochromatography, and surface plasmon resonance biosensors. In addition, we deeply explored the design of haptens for quinoxalines and their metabolites and analyzed the effect of haptens on antibody performance. This paper aims to provide guidance and references for their accurate and sensitive detection, thereby ensuring food safety and human public health.

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