数字农科院2.0

A gain-of-function mutation at the C-terminus of FT-D1 promotes heading by interacting with 14-3-3A and FDL6 in wheat

文献类型： 外文期刊

作者： Li, Yuting;Xiong, Hongchun;Guo, Huijun;Xie, Yongdun;Zhao, Linshu;Gu, Jiayu;Li, Huiyuan;Zhao, Shirong;Ding, Yuping;Zhou, Chunyun;Fang, Zhengwu;Liu, Luxiang

作者机构：

关键词： wheat;FT-D1;heading date;plant height;FAC;ELF5

期刊名称： PLANT BIOTECHNOLOGY JOURNAL

ISSN： 1467-7644

年卷期： 2024 年

页码：

收录情况： SCIE（2024版）

摘要： Vernalization and photoperiod pathways converging at FT1 control the transition to flowering in wheat. Here, we identified a gain-of-function mutation in FT-D1 that results in earlier heading date (HD), and shorter plant height and spike length in the gamma ray-induced eh1 wheat mutant. Knockout of the wild-type and overexpression of the mutated FT-D1 indicate that both alleles are functional to affect HD and plant height. Protein interaction assays demonstrated that the frameshift mutation in FT-D1(eh1) exon 3 led to gain-of-function interactions with 14-3-3A and FDL6, thereby enabling the formation of florigen activation complex (FAC) and consequently activating a flowering-related transcriptomic programme. This mutation did not affect FT-D1(eh1) interactions with TaNaKR5 or TaFTIP7, both of which could modulate HD, potentially via mediating FT-D1 translocation to the shoot apical meristem. Furthermore, the 'Segment B' external loop is essential for FT-D1 interaction with FDL6, while residue Y85 is required for interactions with TaNaKR5 and TaFTIP7. Finally, the flowering regulatory hub gene, ELF5, was identified as the FT-D1 regulatory target. This study illustrates FT-D1 function in determining wheat HD with a suite of interaction partners and provides genetic resources for tuning HD in elite wheat lines.

分类号：

  • 相关文献

[1]TaFT-D1 positively regulates grain weight by acting as a coactivator of TaFDL2 in wheat. Zhang, Yinhui,Liu, Haixia,Wang, Yaojia,Si, Xuemei,Pan, Yuxue,Guo, Mengjiao,Wu, Meijuan,Li, Yuanhao,Liu, Hongxia,Zhang, Xueyong,Hou, Jian,Li, Tian,Hao, Chenyang. 2025

[2]An efficient method for estimating wheat heading dates using uav images. Licheng Zhao,Wei Guo,Jian Wang,Haozhou Wang,Yulin Duan,Cong Wang,Wenbin Wu,Yun Shi. 2021

[3]A point mutation in the zinc finger motif of RID1/EHD2/OsID1 protein leads to outstanding yield-related traits in japonica rice variety Wuyunjing 7. Shikai Hu , Guojun Dong +, Jie Xu , Yan Su , Zhenyuan Shi , Weijun Ye , Yuanyuan Li , Gengmi Li , Bin Zhang , Jiang Hu , Qian Qian , Dali Zeng *, Longbiao Guo *. 2013

[4]充分发掘保护利用生物多样性;促进农业可持续发展——《生物多样性与小麦改良》简评. 李祥洲. 1997

[5]The Genomic Variation and Differentially Expressed Genes on the 6P Chromosomes in Wheat-Agropyron cristatum Addition Lines 5113 and II-30-5 Confer Different Desirable Traits. Yang, Wenjing,Han, Haiming,Guo, Baojin,Qi, Kai,Zhang, Jinpeng,Zhou, Shenghui,Yang, Xinming,Li, Xiuquan,Lu, Yuqing,Liu, Weihua,Liu, Xu,Li, Lihui. 2023

[6]Gene Mapping and Identification of a Missense Mutation in One Copy of VRN-A1 Affects Heading Date Variation in Wheat. Xue, Qianwen,Xiong, Hongchun,Zhou, Chunyun,Guo, Huijun,Zhao, Linshu,Xie, Yongdun,Gu, Jiayu,Zhao, Shirong,Ding, Yuping,Xu, Le,Liu, Luxiang. 2023

[7]Transcriptome profiling of developing leaf and shoot apices to reveal the molecular mechanism and co-expression genes responsible for the wheat heading date. Yuxin Yang,Xueying Zhang,Lifen Wu,Lichao Zhang,Guoxiang Liu,Chuan Xia,Xu Liu,Xiuying Kong. 2021

[8]Transcriptome profiling of developing leaf and shoot apices to reveal the molecular mechanism and co-expression genes responsible for the wheat heading date. Yuxin Yang,Xueying Zhang,Lifen Wu,Lichao Zhang,Guoxiang Liu,Chuan Xia,Xu Liu,Xiuying Kong. 2021

[9]Identification of novel candidate gene associated with early heading on chromosome 5B in wheat mutant jg1489. Qingxia Chang,Hongchun Xiong,Huijun Guo,Yongdun Xie,Linshu Zhao,Jiayu Gu,Huiyuan Li,Shirong Zhao,Yuping Ding,Yumei Zhang,Luxiang Liu. 2025

[10]QTL Analysis of Spike Morphological Traits and Plant Height in Winter Wheat (Triticum aestivum L.) Using a High-Density SNP and SSR-Based Linkage Map. Zhai, Huijie,Feng, Zhiyu,Li, Jiang,Liu, Xinye,Ni, Zhongfu,Sun, Qixin,Zhai, Huijie,Feng, Zhiyu,Li, Jiang,Liu, Xinye,Ni, Zhongfu,Sun, Qixin,Xiao, Shihe. 2016

[11]Wheat breeding history reveals synergistic selection of pleiotropic genomic sites for plant architecture and grain yield. Aili Li,Chenyang Hao,Zhenyu Wang,Shuaifeng Geng,Meiling Jia,Fang Wang,Xiang Han,Xingchen Kong,Lingjie Yin,Shu Tao,Zhongyin Deng,Ruyi Liao,Guoliang Sun,Ke Wang,Xingguo Ye,Chengzhi Jiao,Hongfeng Lu,Yun Zhou,Dengcai Liu,Xiangdong Fu,Xueyong Zhang,Long Mao. 2022

[12]Genetic mapping and identification of Rht8-B1 that regulates plant height in wheat. Chunyun Zhou,Hongchun Xiong,Meiyu Fu,Huijun Guo,Linshu Zhao,Yongdun Xie,Jiayu Gu,Shirong Zhao,Yuping Ding,Yuting Li,Xuejun Li,Luxiang Liu. 2023

[13]A Glu209Lys substitution in DRG1/TaACT7, which disturbs F-actin organization, reduces plant height and grain length in bread wheat. Xie, Zhencheng,Zhang, Lichao,Zhang, Qiang,Lu, Yan,Dong, Chunhao,Li, Danping,Liu, Xu,Xia, Chuan,Kong, Xiuying. 2023

[14]Genetic analysis and mapping of dwarf gene without yield penalty in a γ-ray-induced wheat mutant. Qingguo Wang,Hongchun Xiong,Huijun Guo,Linshu Zhao,Yongdun Xie,Jiayu Gu,Shirong Zhao,Yuping Ding,Luxiang Liu. 2023

[15]Identification of Rht1 for plant height reduction in two wheat mutants and the effects on yield components. Xinshe Zhou,Qingguo Wang,Huijun Guo,Yongdun Xie,Linshu Zhao,Jiayu Gu,Huiyuan Li,Shirong Zhao,Yuping Ding,Jie Guo,Hongchun Xiong,Luxiang Liu. 2025

[16]30个小麦新品系抗条锈病基因分析及成株期抗病性评价. 冯晶,蔺瑞明,林凤,徐世昌. 2013

[17]小麦抗菌蛋白编码基因BS108的克隆及其转基因抗病小麦的创制. 李钊,周淼平,张增艳,庄洪涛,徐惠君,杜丽璞,叶兴国. 2010

[18]渗透调节物质及有机附加物对小麦体细胞胚发生影响的研究(英文). 孙朝霞,侯思宇,王玉国. 2008

[19]普通小麦品种辐射敏感性模糊聚类分析<英文>. 冯志杰,王琳清. 1992

[20]基因枪转化小麦主要轰击参数的优化. 闵东红,何莎,张彦,夏兰琴. 2013

作者其他论文 更多>>