数字农科院2.0

Creating Inbred Lines for Heterosis Utilization in Alfalfa

文献类型： 外文期刊

作者： 刘腾飞;;栗露露;;林浩;;牛丽芳

关键词： inbred;;alfalfa

期刊名称： Science China-Life Sciences

ISSN： 1674-7305

年卷期： 2025 年

页码：

收录情况： SCIE（2025版） ; ; CSCD（2025-2026年度） ; ; 科技核心（2024版）

摘要： Alfalfa (Medicago sativa L.) is a perennial species with vegetative propagation capacity, which has been widely cultivated due to its many advantageous traits, such as broad environmental adaptability, high nutritive quality, excellent taste, and nitrogen-fixing ability. Consequently, alfalfa is valued not just for its role in animal nutrition but also for its contribution to environmental sustainability. Cultivated alfalfa is the product of crosses between heterozygous autotetraploid parental lines. The complexity of tetrasomic inheritance hinders the genetic improvement of cultivated alfalfa. Under this system, breeders evaluate hundreds of thousands of seedlings per generation to isolate the rare recombinants possessing the acceptable segregating characteristics. To overcome these challenges, researchers should make efforts to develop alfalfa as an inbred-line-based crop, which is a prerequisite to breeding hybrid alfalfa. Developing elite highly homozygous inbred lines remains challenging primarily because of the nature of self-incompatibility and inbreeding depression, as deleterious alleles exist in the genome in a heterozygous state. Therefore, a deep knowledge of self-incompatibility and inbreeding depression is crucial for overcoming barriers in the breeding of high- performance inbred lines. Based on these findings, we proposed a pipeline to carry out inbred-line-based alfalfa hybrid breeding by genome design methods

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