数字农科院2.0

Synergistic modulation of oxidation state of Pt nanozymes via Pd doping and ZIF-67 support enhances the catalytic efficiency for immunoassay detection

文献类型: 外文期刊

作者: Liu, Zhenjiang;Yang, Ying;Yu, Weiguo;Feng, Jiankun;Chen, Hailong;Li, Runan;Li, Longhua;Xue, Yuan

作者机构:

关键词: Nanozymes;Synergistic modulation;Oxidation state;Catalytic efficiency;Immunoassay

期刊名称: BIOSENSORS & BIOELECTRONICS

ISSN: 0956-5663

年卷期: 2025 年 295 卷

页码:

收录情况: SCIE(2025版) ; ; EI(2025版)

摘要: Modulating the oxidation state of active sites presents a promising strategy for enhancing catalytic performance. However, the intrinsic electronic properties of a single regulatory strategy make it difficult to accurately control the oxidation state of nanozymes. Herein, we design high-efficiency PtXPd1@ZIF-67 nanozymes by integrating two modulation strategies (Pd doping and ZIF-67 support) to effectively regulate the oxidation state of the Pt active center. The results demonstrate that Pt4Pd1@ZIF-67 nanozyme with a moderate oxidation state exhibits the best catalytic activity, which is 1.97- and 3.87-fold higher than that of Pt@ZIF-67 and Pt@ZIF-67-S (S represents the removal of ZIF-67 support), respectively. Theoretical calculations indicate that the moderate oxidation state of Pt enhances the adsorption of OH, thereby reducing the energy barrier of the key reaction step (2*OH -> *O + H2O) and ultimately improving the catalytic activity of nanozyme. Crucially, Pt4Pd1@ZIF-67 nanozyme was successfully employed to develop a novel indirect competitive immunoassay for the detection of zearalenone, with a limit of detection of 0.534 ng L-1. This work provides a potential strategy for the rational design of high catalytic performance nanozymes for immunoassay detection.

分类号:

  • 相关文献

[1]Chromium deposition enhances the tolerance of Chlorella vulgaris to microplastics. Yuanyuan Wei,Xuan Hou,Xiangang Hu,Li Mu. 2025

[2]Flavonoid-rich sesame leaf extract-mediated synthesis of nanozymes: Extraction optimization, chemical composition identification and bioactivity evaluation. Ruiying Zhang,Yufei Liu,Yiqiao Gao,Dengfeng Peng,Qian Luan,Ziliang Li,Xiaoyang Xia,Xia Xiang. 2024

[3]Optimizing cancer therapy through metal organic frameworks-based nanozymes. Qinxin Zhang,Sai Chen,Hongwei Zhang,Zitong Bao,Yangyang Chen,Guangling Zhang,Zhiyong Liu,Jichun Yang,Runhe He,Yatao Liu,Xuetao Tian. 2025

[4]Multi-mode probe based on dual colorimetric and photothermal later flow immunoassay for the ultrasensitive determination of benzo[a]pyrene in vegetable oils. Yuting Yuan,Xiaoqian Tang,Liangxiao Zhang,Qi Zhang,Fei Ma,Peiwu Li. 2025

[5]Dual Fe-Active-Site Engineering in MCOF Nanozymes for Synergistic and Broad-Spectrum Antibacterial Therapy. Jingqi Liu, Guimei Han, Manying Li, Xiaoyang Liu, Yan Tan, Anna Tang, Hongxin Jiang,* Lina Zhu,,* and Deming Kong*. 2025

[6]Nanozyme taxonomy, mechanistic insights, and controllable synthesis strategies: Advances in precision agricultural applications. Fukai Li,Can Zhou,Jiahao Zhao,Kai Li,Mengrui Yang,Nan Cheng,Lina Qiu,Jian Zhou,Liang Li. 2025

[7]Loop 3 of Fungal Endoglucanases of Glycoside Hydrolase Family 12 Modulates Catalytic Efficiency. Yang, Hong,Shi, Pengjun,Liu, Yun,Xia, Wei,Wang, Xiaoyu,Cao, Huifang,Ma, Rui,Luo, Huiying,Bai, Yingguo,Yao, Bin,Liu, Yun,Wang, Xiaoyu.

[8]Molecular Characterization of a Thermophilic Endo-polygalacturonase from Thielavia arenaria XZ7 with High Catalytic Efficiency and Application Potential in the Food and Feed Industries. Tu, Tao,Meng, Kun,Huang, Huoqing,Luo, Huiying,Bai, Yingguo,Ma, Rui,Su, Xiaoyun,Shi, Pengjun,Yang, Peilong,Wang, Yaru,Yao, Bin.

[9]Two Family 11 Xylanases from Achaetomium sp Xz-8 with High Catalytic Efficiency and Application Potentials in the Brewing Industry. Zhao, Liang,Meng, Kun,Bai, Yingguo,Shi, Pengjun,Huang, Huoqing,Luo, Huiying,Wang, Yaru,Yang, Peilong,Yao, Bin,Zhao, Liang,Song, Wei. 2013

[10]Substitution of a non-active-site residue located on the T3 loop increased the catalytic efficiency of endo-polygalacturonases. Tu, Tao,Pan, Xia,Meng, Kun,Luo, Huiying,Ma, Rui,Wang, Yuan,Yao, Bin. 2016

[11]Improving the Catalytic Performance of a Talaromyces leycettanus alpha-Amylase by Changing the Linker Length. Zhang, Duoduo,Luo, Xuegang,Zhang, Tongcun,Zhang, Duoduo,Luo, Xuegang,Zhang, Tongcun,Tu, Tao,Wang, Yuan,Li, Yeqing,Zheng, Fei,Wang, Xiaoyu,Bai, Yingguo,Huang, Huoqing,Su, Xiaoyun,Yao, Bin,Luo, Huiying.

[12]A novel thermophilic xylanase from Achaetomium sp Xz-8 with high catalytic efficiency and application potentials in the brewing and other industries. Zhao, Liang,Meng, Kun,Shi, Pengjun,Bai, Yingguo,Luo, Huiying,Huang, Huoqing,Wang, Yaru,Yang, Peilong,Yao, Bin,Zhao, Liang. 2013

[13]Improvement of the catalytic performance of a Bispora antennata cellulase by replacing the N-terminal semi-barrel structure. Zheng, Fei,Wang, Xiaoyu,Xie, Xiangming,Zheng, Fei,Huang, Huoqing,Wang, Xiaoyu,Tu, Tao,Liu, Qiong,Meng, Kun,Wang, Yuan,Su, Xiaoyun,Luo, Huiying.

[14]Fusion of a proline-rich oligopeptide to the C-terminus of a ruminal xylanase improves catalytic efficiency. Dong R.,Liu X.,Wang Y.,Qin X.,Wang X.,Zhang H.,Wang Y.,Luo H.,Yao B.,Bai Y.,Tu T.. 2022

[15]Improvement of thermostability and catalytic efficiency of glucoamylase from Talaromyces leycettanus JCM12802 via site-directed mutagenesis to enhance industrial saccharification applications. Lige Tong,Jie Zheng,Xiao Wang,Xiaolu Wang,Huoqing Huang,Haomeng Yang,Tao Tu,Yuan Wang,Yingguo Bai,Bin Yao,Huiying Luo,Xing Qin. 2021

[16]Identification and Mutation Analysis of Nonconserved Residues on the TIM-Barrel Surface of GH5_5 Cellulases for Catalytic Efficiency and Stability Improvement. Zheng, Jie,Liu, Han-Qing,Qin, Xing,Yang, Kun,Tian, Jian,Wang, Xiao-Lu,Wang, Ya-Ru,Wang, Yuan,Yao, Bin,Luo, Hui-Ying,Huang, Huo-Qing. 2022

[17]Effectiveness of ruminal xylanase with an extra proline-rich C-terminus on lignocellulosic biomass degradation. Dong R.,Liao M.,Liu X.,Penttinen L.,Hakulinen N.,Qin X.,Wang X.,Huang H.,Luo H.,Yao B.,Bai Y.,Tu T.. 2023

[18]MECE: a method for enhancing the catalytic efficiency of glycoside hydrolase based on deep neural networks and molecular evolution. Liu, Hanqing,Guan, Feifei,Liu, Tuoyu,Yang, Lixin,Fan, Lingxi,Liu, Xiaoqing,Luo, Huiying,Wu, Ningfeng,Yao, Bin,Tian, Jian,Huang, Huoqing. 2023

[19]Characterization of a novel cold-adapted GH1 β-glucosidase from Psychrobacillus glaciei and its application in the hydrolysis of soybean isoflavone glycosides. Jinjian He,Jiajing Duan,Pinglian Yu,Yuying Li,Mansheng Wang,Xiu Zhang,Zishu Chen,Pengjun Shi. 2024

[20]Catalytic boost in dual-active sites hierarchical hollow nanozymes: An enhanced robust and sensitive immunochromatographic assay for Aspergillus flavus. Meijuan Liang,Xiaofeng Hu,Du Wang,Xiaoqian Tang,Qi Zhang,Peiwu Li. 2025

作者其他论文 更多>>