1C. Elegans as an in vivo model system for the phenotypic drug discovery for treating paraquat poisoning

作者： Ji P.; Li H.; Jin Y.; Peng Y.; Zhao L.; Wang X.; SCIE（2022版）

机构： College of Life Science and Technology; Changchun University of Science and Technology; Changchun; China; Laboratory of Chemical Biology; Changchun Institute of Applied Chemistry (CIAC); Chinese Academy of Sciences (CAS); Department of Immunology; Department of Cell and Systems Biology; University of Toronto; Toronto; Canada; Key Laboratory of Special Animal Molecular Biology of Jilin Province; Specialty Research Institute; Chinese Academy of Agricultural Sciences; Department of Applied Chemistry and Engineering; University of Science and Technology of China; Hefei; Beijing National Laboratory for Molecular Sciences; Beijing;

来源：PeerJ

关键词： antidote green fluorescent protein malonaldehyde reactive oxygen metabolite ubidecarenone animal experiment animal model Article C57BL 6 mouse Caenorhabditis elegans controlled study drug development Escherichia coli in vivo study lifespan lung parenchyma male mitochondrion mouse mouse model nonhuman paraquat poisoning pharynx phenotype survival rate validity Biological organs Coenzymes Herbicides Mitochondria C elegan Coenzyme Q10 Drug discovery Elegans In-vivo Malondialdehyde Mice models Paraquat Phenotypic drug discovery Reactive oxygen species Mammals

年份：2022