数字农科院2.0

Polymorphisms of BMPR-IB gene and their relationship with litter size in goats

文献类型： 外文期刊

作者： Chu, M. X.;Di, R.;Cao, G. L.;Feng, T.;Fang, L.;Ma, Y. H.;Li, K.;Zhao, X. H.;Wang, J. Y.;Zhang, Y. J.;Jin, M.

作者机构：

关键词： goats;Prolificacy;Bone morphogenetic protein receptor IB gene;PCR-SSCP;Internet resource.

期刊名称： MOLECULAR BIOLOGY REPORTS

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： The bone morphogenetic protein receptor IB (BMPR-IB) gene was studied as a candidate gene for the prolificacy of goats. According to mRNA sequence of ovine BMPR-IB gene, ten pairs of primers were designed to detect single nucleotide polymorphisms (SNPs) of exon 1, exon 2, exon 6 to exon 10 and 3o untranslated region (UTR) of the BMPR-IB gene in both high prolificacy breed (Jining Grey goat) and low prolificacy breeds (Wendeng Dairy and Inner Mongolia Cashmere goats) by polymerase chain reaction (PCR)-single strand conformation polymorphism (SSCP) method. Only the products amplified by primers P8 and P10 of the 3oUTR displayed polymorphisms. For primer P8, three genotypes (AA, AB and BB) were detected in Jining Grey and Wendeng Dairy goats, two genotypes (AA and AB) were in Inner Mongolia Cashmere goats. Sequencing revealed one mutation (71CT) of the BMPR-IB gene in genotype BB compared with AA. The differences of least squares mean (LSM) for litter size between genotypes AA, AB and BB were non-significant (P > 0.05) in Jining Grey goats. For primer P10, three genotypes (CC, CD and DD) were detected in Jining Grey and Wendeng Dairy goats and one genotype (CC) in Inner Mongolia Cashmere goats. Sequencing revealed one mutation (130TC) of the BMPR-IB gene in genotype DD compared with CC. The differences of LSM for litter size between genotypes CC, CD and DD were non-significant (P > 0.05) in Jining Grey goats. These results preliminarily showed that the detected loci of the BMPR-IB gene had no significant effect on prolificacy of Jining Grey goats.

分类号： Q7

  • 相关文献

[1]Polymorphisms of coding region of BMPR-IB gene and their relationship with litter size in sheep. Chu, Mingxing,Fang, Li,Di, Ran,Cao, Guiling,Feng, Tao,Tang, Qianqian,Ma, Yuehui,Li, Kui,Jia, Lihua,Chen, Hongquan,Zhang, Yingjie,Jin, Mei. 2011

[2]Mutations in BMPR-IB and BMP-15 genes are associated with litter size in Small Tailed Han sheep (Ovis aries). Chu, M. X.,Liu, Z. H.,Jiao, C. L.,He, Y. Q.,Fang, L.,Ye, S. C.,Chen, G. H.,Wang, J. Y.. 2007

[3]Polymorphism in exon 2 of INHBB gene and its relationship with litter size in Jining Grey goats. Chu, M. X.,Fang, L.,Di, R.,Cao, G. L.,Feng, T.,Peng, Z. L.,Chen, H. Q.,Zhang, Y. J.,Li, N.. 2012

[4]Polymorphisms of KiSS-1 and GPR54 genes and their relationships with litter size in sheep. Chu, Mingxing,Feng, Tao,Cao, Guiling,Fang, Li,Di, Ran,Tang, Qianqian,Huang, Dongwei,Ma, Yuehui,Li, Kui,Xiao, Chaoting,Fu, Yan,Li, Ning.

[5]Novel SNPs of the bovine CACNA2D1 gene and their association with carcass and meat quality traits. Yuan, Zheng Rong,Xu, Shang Zhong.

[6]Analysis on DNA sequence of KiSS-1 gene and its association with litter size in goats. Cao, G. L.,Chu, M. X.,Fang, L.,Di, R.,Feng, T.,Li, N..

[7]PCR-SSCP polymorphism of inhibin beta(A) gene in some sheep breeds. Chu, M. X.,Xiao, C. T.,Fu, Y.,Fang, L.,Ye, S. C.. 2007

[8]Ovine prion protein genotype frequencies in northwestern China. Zhao, C. -L.,Wu, R.,Liu, L.,Zhang, X. -L.,Wang, C.,Wang, F.,Diao, X. -L.,Guan, H. -W.,Wang, X.,Zhou, L.,Wu, R.,Li, F. -D.. 2012

[9]Relationship between the polymorphisms of 5 ' regulation region of prolactin gene and milk traits in Chinese Holstein dairy cows. Li, JT,Wang, AH,Chen, P,Li, HB,Zhang, CS,Du, LX. 2006

[10]Polymorphism of 5' regulatory region of ovine FSHR gene and its association with litter size in Small Tail Han sheep. Chu, M. X.,Huang, D. W.,Feng, T.,Cao, G. L.,Fang, L.,Di, R.,Tang, Q. Q.,Ma, Y. H.,Li, K.,Guo, X. H.,Guo, X. H.,Feng, C. J.,Li, Y..

[11]ASSOCIATION BETWEEN POLYMORPHISMS IN THE SLC27A1 GENE AND MILK PRODUCTION TRAITS IN CHINESE HOLSTEIN CATTLE. Lv, Yanfei,Wei, Caihong,Zhang, Li,Lu, Guobin,Du, Lixin,Lv, Yanfei,Liu, Kaidong. 2011

[12]Polymorphisms in the myostatin gene and their association with growth and carcass traits in duck. Lu, Junqing,Hou, Shuisheng,Huang, Wei,Yu, Junying,Wang, Wenwu. 2011

[13]Sequence Variations in the Bovine IGF-I and IGFBP3 Genes and Their Association with Growth and Development Traits in Chinese Beef Cattle. Gao Xue,Shi Ming-yan,Li Jun-ya,Ren Hong-yan,Xu Shang-zhong,Shi Ming-yan,Xu Xiu-rong. 2009

[14]Further evidence from SSCP and ITS DNA sequencing support Trypanosoma evansi and Trypanosoma equiperdum as subspecies or even strains of Trypanosoma brucei. Wen, Yan-Zi,Lun, Zhao-Rong,Lai, De-Hua,Lun, Zhao-Rong,Zhu, Xing-Quan,Lun, Zhao-Rong,Hide, Geoff,Lun, Zhao-Rong,Hide, Geoff.

[15]Single nucleotide polymorphism discovery of peroxisome proliferators-activated receptors gamma gene and its association with carcass traits in duck. Wu, Yan,Liu, Xiaolin,Wang, Jie,Hou, Shuisheng. 2008

[16]Screening for S32G mutation of BMP15 gene in 18 goat breeds. Feng, Tao,Feng, Tao,Chu, Ming-Xing,Cao, Gui-Lin,Huang, Dong-Wei,Di, Ran,Liu, Qiu-Yue,Pan, Zhang-Yuan,Jin, Mei,Zhang, Ying-Jie. 2014

[17]Polymorphic Study of FecX(G), FecG(H) and Fec(B) Mutations in Four Domestic Sheep Breeds in the Lower Yellow River Valley of China. Zhang, Chuan-Sheng,Geng, Li-Ying,Du, Li-Xin. 2011

[18]The genetic diversity of both FecB gene and microsatellite GC101 is associated with reproduction selection in sheep. Pan, Zhangyuan,Hu, Wenping,Di, Ran,Lin, Qinyue,Wang, Xiangyu,Yin, Dehua,Chu, Mingxing,Zhang, Baoyun,Wang, Pingqing.

[19]Polymorphism of insulin-like growth factor 1 gene and its association with litter size in Small Tail Han sheep. He, J. N.,Chu, M. X.,Feng, T.,Di, R.,Fang, L.,Huang, D. W.,Tang, Q. Q.,Zhang, B. Y.,Wang, P. Q.,Cao, G. L.,Li, N..

[20]Polymorphisms of caprine POU1F1 gene and their association with litter size in Jining Grey goats. Feng, T.,Chu, M. X.,Cao, G. L.,Tang, Q. Q.,Di, R.,Fang, L.,Li, N..

作者其他论文 更多>>