数字农科院2.0

Natural variation in the GhTTL promoter modulates cotton fiber elongation through the GhTALE-GhTTL-GhBIN2 module

文献类型： 外文期刊

作者： Liu, Le;Liu, Zhao;Fan, Liqiang;Yu, Mengli;Qanmber, Ghulam;Wang, Longfei;Li, Yujun;Li, Fuguang;Jin, Shuangxia;Yang, Zuoren

作者机构：

关键词： cotton fiber;brassinosteroid;GWAS;GhTTL;GhBIN2

期刊名称： PLANT COMMUNICATIONS

ISSN： 2590-3462

年卷期： 2025 年 6 卷 10 期

页码：

收录情况： SCIE（2025版） ; ; CSCD（2025-2026年度）

摘要： In cotton, fiber length is a key determinant of industrial utility and is one of the most important agricultural traits shaped during domestication. However, the genetic determinants and molecular mechanisms underlying natural variation in fiber length remain poorly characterized. In this study, we identified GhTTL as a critical positive regulator of fiber elongation through genome-wide association study (GWAS). Natural polymorphisms in the cis-regulatory element of the GhTTL promoter region were found to significantly affect its binding affinity for the transcription factor GhTALE, thereby modulating GhTTL expression across diverse cotton populations. Mechanistic investigations revealed that GhTTL interacts with GhBIN2, a central negative regulator of the brassinosteroid (BR) signaling pathway, and anchors it to the cell membrane. This reduces cytoplasmic GhBIN2 levels, preventing it from associating with GhBES1, a master transcription factor of BR signaling. As a result, GhBES1 localizes to the nucleus, where it promotes fiber cell elongation. These findings elucidate the molecular basis of natural variation in cotton fiber length and provide deeper insights into the regulation of fiber elongation. In addition, this study identifies potential targets for genetic improvement to enhance cotton fiber quality and yield.

分类号：

  • 相关文献

[1]Mapping the Phosphorylation Regulatory Network of Single-Celled Fibre Elongation Mediated by GhBIN2 in Cotton. Liu, Le,Yu, Mengli,Wang, Longfei,Qanmber, Ghulam,Fan, Liqiang,Li, Yujun,Liu, Zhao,Wang, Xuwen,Liu, Li,Li, Fuguang,Jin, Shuangxia,Yang, Zuoren. 2025

[2]蛋鸡资源群体的盲肠长度全基因组关联分析. 王星果,曲亮,卢建,窦套存,马猛,胡玉萍,沈曼曼,郭军,李尚民,王克华. 2018

[3]中国籼稻群体的遗传结构解析及12个株型性状的全基因组关联分析. 鲁清,章孟臣,魏兴华. 2015

[4]北京油鸡血清IgG含量的GWAS初步分析. 张磊,刘冉冉,赵桂苹,文杰,郑麦青,吴丹,胡耀东,李鹏,刘丽. 2011

[5]黄瓜发芽期耐热性评价及全基因组关联分析. 张松,苗晗,宋子超,薄凯亮,王烨,顾兴芳,张圣平. 2019

[6]功能基因筛选方法的研究进展. 姚雅馨,喇永富,汤继顺,贺小云,张壮彪,储明星. 2020

[7]玉米叶片叶绿素含量的全基因组关联性分析. 滕守振1,,2 汪海2 梁海生1,,2 辛红佳2 李圣彦2 郎志宏2. 2017

[8]基于通路分析方法诠释肉鸡体重性状全基因组关联研究. 王杰,刘璐,刘杰,赵桂苹,刘冉冉,郑麦青,文杰. 2017

[9]黄瓜核心种质幼苗耐低温性评价及GWAS分析. 王伟平,宋子超,薄凯亮,董邵云,魏爽,苗晗,李锦斌,张圣平,顾兴芳. 2019

[10]黄瓜核心种质幼苗耐热性评价及GWAS分析. 魏爽,张松,薄凯亮,王伟平,苗晗,董邵云,顾兴芳,张圣平. 2019

[11]利用两种统计模型对中国肉用西门塔尔牛屠宰性状的全基因组关联分析. 常天鹏,夏江威,宝金山,金生云,朱波,徐凌洋,陈燕,张路培,高雪,李俊雅,高会江. 2018

[12]基于SNP标记的小麦籽粒性状全基因组关联分析. 张芳,任毅,曹俊梅,李法计,夏先春,耿洪伟. 2021

[13]小麦芒基因定位及其与农艺性状的相关性分析. 李玲,刘盼,张蕾,张浩,贾继增,高丽锋. 2021

[14]桃花花型（铃形/蔷薇形）基因型鉴定、分子标记开发与利用. 吉爽秋,王力荣,李勇,朱更瑞,曹珂,方伟超,陈昌文,王新卫,张琦,吴金龙. 2022

[15]油菜籽脂肪组成的遗传结构剖析. 杨雨婷,于文凯,徐颖,王会,梅德圣,蒋立希,胡琼,刘佳. 2022

[16]基于GWAS和BSA-seq挖掘辣椒果实中辣椒红色素含量的QTL区间及候选基因. 班国梁,曹亚从,张正海,于海龙,吴华茂,李戎轩,赵红,张伟丽,聂智星,宋红霞,王立浩. 2025

[17]基于MAGIC群体的烟草抗黑胫病全基因组关联分析. 潘怡,刘洪泰,吉白璐,王红,黄立钰,程立锐. 2024

[18]低磷胁迫下大豆苗期根系性状全基因组关联分析. 孙畅,刘美玲,刘子君,杨光,梁腾月,周宣汝,赵悦如,张洛桐,谷勇哲,敖雪. 2024

[19]基于无人机高通量作物表型技术研究进展（英文）. 张家欣,余世浩,牛牧远,叶育璐,徐新阳,王远,郭三堆,Rashid Bushra,梁成真,孟志刚. 2025

[20]大豆耐储藏性相关位点的GWAS定位及候选基因的单倍型分析. 朱沂昕,李重阳,王俊,李敏敏,耿雅婷,高华伟,刘立科. 2025

作者其他论文 更多>>