Characterization of a blaCTX-M-3, blaKPC-2 and blaTEM-1B co-producing IncN plasmid in Escherichia coli of chicken origin
文献类型: 外文期刊
作者: WANG W.-J.;WANG Y.-F.;JIN Y.-J.;SONG W.-Q.;LIN J.-M.;ZHANG Y.;TONG X.-R.;TU J.;LI R.-C.;LI T.
作者机构:
关键词: blaCTX-M-3;blaKPC-2;blaTEM-1B;Escherichia coli;IncN;plasmid
期刊名称: Journal of Integrative Agriculture
ISSN: 2095-3119
年卷期: 2023 年 22 卷 1 期
页码:
收录情况: SCIE(2023版) ; ; CSCD(2023-2024年度) ; ; 科技核心(2023版) ; ; 农林核心(2020版)
摘要: An extensively drug-resistant (XDR) Escherichia coli strain 258E was isolated from an anal swab sample of a chicken farm of Anhui Province in China. Genomic analyses indicated that the strain 258E harbors an incompatibility group N (IncN) plasmid pEC258-3, which co-produces blaCTX-M-3, blaKPC-2, blaTEM-1B, qnrS1, aac(6´)-Ib-cr, dfrA14, arr-3, and aac(6´)-Ib3. Multiple genome arrangement analyses indicated that pEC258-3 is highly homologous with pCRKP-1-KPC discovered in Klebsiella pneumoniae from a patient. Furthermore, conjugation experiments proved that plasmid pEC258-3 can be transferred horizontally and may pose a significant potential threat in animals, community and hospital settings. © 2023 CAAS. Publishing services by Elsevier B.V
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