数字农科院2.0

Chemical Constituents of Anaphalis hancockii Maxim

文献类型： 外文期刊

作者： Li, Guo-Li;Gong, Zheng;He, Yi-lin;Li, Zhao-Cai;Shen, Tong

作者机构：

关键词： Anaphalis hancockii Maxim;antichlamydial activity;antifungal activity;isobenzofuranones

期刊名称： CHEMISTRY & BIODIVERSITY

ISSN： 1612-1872

年卷期： 2025 年

页码：

收录情况： SCIE（2025版）

摘要： Twenty-seven compounds were isolated from Anaphalis hancockii Maxim in Qinghai Province, China, including 7 isobenzofuranones (1-7), 8 flavonoids (8-15), and 12 other compounds (16-27). Compound 1 is a new isobenzofuranone. The structures of the compounds were determined by analyzing their HRESIMS, 1D- and 2D-nuclear magnetic resonance (NMR), electronic circular dichroism (ECD) and comparing them to the reported data. This study is the first report of A. hancockii Maxim's chemical composition, a perennial herb belonging to the genus Anaphalis. Isobenzofuranones are the main bioactive constituents of the genus Anaphalis; thus, seven isobenzofuranones (1-7) were assessed for their antibacterial and antichlamydial activities. Compound 6 showed moderate activity against six different pathogenic fungi. The result suggested that Compound 5 might be a promising class of therapeutic agents for chlamydial infections.

分类号：

  • 相关文献

[1]Jatrolignans C and D: New Neolignan Epimers from Jatropha curcas. He, Yi-Lin,Huang, Pei-Zhi,Yang, Hong-Ying,Feng, Wei-Jiao,Li, Zhao-Cai,Gao, Kun. 2022

[2]Design, Synthesis, DFT Study and Antifungal Activity of Pyrazolecarboxamide Derivatives. Mu, Jin-Xia,Shi, Yan-Xia,Li, Bao-Ju,Yang, Ming-Yan,Sun, Zhao-Hui,Liu, Xing-Hai,Sun, Na-Bo.

[3]Synthesis, Crystal Structure, DFT Studies and Antifungal Activity of 5-(4-Cyclopropyl-5-((3-fluorobenzyl)sulfonyl)-4H-1,2,4-triazol-3-yl)-4-methyl-1,2,3-thiadiazole. Zhai Zhi-Wen,Yang Ming-Yan,Sun Zhao-Hui,Weng Jian-Quan,Tan Cheng-Xia,Liu Xing-Hai,Shi Yan-Xia,Li Bao-Ju,Zhang Yong-Gang. 2016

[4]Synthesis and Antifungal Activity of 1,2,4-triazole Derivatives Containing Cyclopropane Moiety. Tan, Cheng-Xia,Weng, Jian-Quan,Liu, Xing-Hai,Zhao, Wei-Guang,Shi, Yan-Xia,Li, Bao-Ju. 2012

[5]Microwave-Assisted Synthesis and Antifungal Activity of Some Novel Thioethers Containing 1,2,4-Triazole Moiety. Min, Li-Jing,Shi, Yan-Xia,Li, Bao-Ju,Wu, Hong-Ke,Sun, Zhao-Hui,Liu, Xing-Hai,Zhang, Yong-Gang. 2015

[6]Identification and antifungal assay of a wheat beta-1,3-glucanase. Liu, Baoye,Lu, Yan,Xin, Zhiyong,Zhang, Zengyan. 2009

[7]Synthesis of Some Novel Hydrazone Derivatives as Antifungal Agents. Wang, Qiao,Yang, Ming-Yan,Sun, Zhao-Hui,Weng, Jian-Quan,Tan, Cheng-Xia,Liu, Xing-Hai,Shi, Yan-Xia,Li, Bao-Ju.

[8]Synthesis and Bioactivities of Novel 1,3,4-oxadiazole Derivatives Containing Pyridine Moiety. Sun, Guo-Xiang,Sun, Zhao-Hui,Yang, Ming-Yan,Wu, Hong-Ke,Weng, Jian-Quan,Tan, Cheng-Xia,Liu, Xing-Hai,Shi, Yan-Xia,Li, Bao-Ju,Zhang, Yong-Gang. 2014

[9]Microwave Assisted Synthesis and Antifungal Activity of Some Novel Hydrazones Containing Pyridine Moiety. Min, Li-Jing,Yang, Ming-Yan,Zhai, Zhi-Wen,Weng, Jian-Quan,Tan, Cheng-Xia,Liu, Xing-Hai,Shi, Yan-Xia,Li, Bao-Ju,Zhang, Yong-Gang.

[10]Design, Synthesis, Antifungal Activities and 3D-QSAR of New N,N '-Diacylhydrazines Containing 2,4-Dichlorophenoxy Moiety. Sun, Na-Bo,Jin, Jian-Zhong,Shi, Yan-Xia,Li, Bao-Ju,Liu, Xing-Hai,Tan, Cheng-Xia,Weng, Jian-Quan,Ma, Yi. 2013

[11]Synthesis, antifungal activities and 3D-QSAR study of N-(5-substituted-1,3, 4-thiadiazol-2-yl)cyclopropanecarboxamides. Shi, Yan-Xia,Li, Bao-Ju,Liu, Xing-Hai,Ma, Yi,Zhang, Chuan-Yu,Dong, Wei-Li,Pan, Li,Wang, Bao-Lei,Li, Zheng-Ming. 2009

[12]Synthesis, Crystal Structure, DFT Studies and Biological Activity of a Novel Schiff Base Containing Triazolo [4,3-a]pyridine Moiety. Shen Zhong-Hua,Yang Ming-Yan,Sun Zhao-Hui,Weng Jian-Quan,Tan Cheng-Xia,Liu Xing-Hai,Shi Yan-Xia,Li Bao-Ju,Zhao Wei-Guang. 2016

[13]Synthesis and Bioactivity of Novel Carvacrol and Thymol Derivatives Containing 5-Phenyl-2-furan. Li, Xinghai,Cui, Zining,Nishida, Yoshihiro,Cui, Zining. 2014

[14]Microwave assisted synthesis, antifungal activity, DFT and SAR study of 1,2,4-triazolo[4,3-a]pyridine derivatives containing hydrazone moieties. Mu, Jin-Xia,Wu, Hong-Ke,Sun, Zhao-Hui,Yang, Ming-Yan,Liu, Xing-Hai,Shi, Yan-Xia,Li, Bao-Ju. 2016

[15]JAK/STAT signaling pathway-mediated immune response in silkworm (Bombyx mori) challenged by Beauveria bassiana. Geng, Tao,Lv, Ding-Ding,Huang, Yu-Xia,Hou, Cheng-Xiang,Qin, Guang-Xing,Guo, Xi-Jie,Hou, Cheng-Xiang,Qin, Guang-Xing,Guo, Xi-Jie.

[16]Design, Synthesis and Bioactivity of N-Glycosyl-N '-(5-substituted phenyl-2-furoyl) Hydrazide Derivatives. Cui, Zining,Nishida, Yoshihiro,Su, Hang,Jiang, Jiazhen,Yang, Xinling,Cui, Zining. 2014

[17]Myroides odoratimimus, a biocontrol agent from the rhizosphere of tobacco with potential to control Alternaria alternata. You, C.,Zhang, C.,Feng, C.,Wang, J.,Kong, F..

[18]Two new carene-type monoterpenes from aerial parts of Ageratina adenophora. Wang, Hong-Feng,Xu, Qiao-Lin,Zhang, Mei,Zhou, Zhong-Yu,Tan, Jian-Wen,Liu, Wan-Xue,Wan, Fang-Hao.

[19]Synthesis, Crystal Structure and Antifungal Activity of 2-((2-Fluorobenzyl)thio)-5-(pyridin-4-yl)-1,3,4-oxadiazole. Sun Guo-Xiang,Zhai Zhi-Wen,Sun Zhao-Hui,Weng Jian-Quan,Tan Cheng-Xia,Liu Xing-Hai,Shi Yan-Xia,Li Bao-Ju. 2016

[20]Solvent- and Catalyst-free Synthesis and Antifungal Activities of alpha-Aminophosphonate Containing Cyclopropane Moiety. Shi Yan-xia,Li Bao-ju,Pan Li,Liu Xing-hai,Wang Bao-lei,Wang Su-hua,Li Zheng-ming. 2010

作者其他论文 更多>>