Research Progress on the Regulation and Developmental Utilization of Bioactive Metabolites Synthesis in Floccularia luteovirens
文献类型: 外文期刊
作者: Tongjia Shi;Lihua Tang;Siyuan Gou;Wensheng Li;Chunxiao Xu;Xu Zhao
作者机构:
关键词: bioactivity;environmental regulation;Floccularia luteovirens;liquid-state fermentation;metabolites;multi-omics
期刊名称: Journal of Fungi
ISSN:
年卷期: 2025 年 11 卷 12 期
页码:
收录情况: SCIE(2025版)
摘要: Floccularia luteovirens is a rare edible and medicinal fungus endemic to the Qinghai–Tibet Plateau, prized for its abundance of high-value bioactive metabolites such as polysaccharides, terpenoids, and ergothioneine, which exhibit a variety of biological activities including immunomodulatory, antioxidant, and antitumor effects. Due to the current lack of successful domestication and limited wild resources, liquid fermentation technology has become an important strategy for the large-scale production of its mycelium and bioactive components. This review systematically summarizes the biological characteristics of F. luteovirens, the diversity of its metabolites, biosynthetic pathways, regulatory mechanisms influenced by environmental factors, and the application of multi-omics technologies in related research. It is suggested that future studies should integrate multi-omics approaches to elucidate its stress response and metabolic regulatory networks, and achieve high-value utilization of this resource through stress-resistant breeding and optimization of fermentation processes.
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