数字农科院2.0

Phased T2T genome assemblies facilitate the mining of disease-resistance genes in Vitis davidii

文献类型： 外文期刊

作者： Luo, Yuanyuan;Liu, Zhenya;Jin, Zhongxin;Li, Peng;Tan, Xibei;Cao, Shuo;Wang, Xu;Liu, Zhongqi;Shi, Xiaoya;Huang, Siyang;Gu, Liyuan;Fan, Xiucai;Jiang, Jianfu;Sun, Lei;Zhou, Yongfeng;Liu, Chonghuai;Xu, Xiaodong;Ma, Zhiyao;Zhang, Ying

作者机构：

关键词： （2-2-2）

期刊名称： HORTICULTURE RESEARCH

ISSN： 2662-6810

年卷期： 2025 年 12 卷 2 期

页码：

收录情况： SCIE（2025版） ; ; CSCD（2025-2026年度） ; ; 科技核心（2024版） ; ; 农林核心（2024版）

摘要： Grape is an important fruit crop, and its production faces significant threat from diseases, resulting in substantial economic loss. Wild grape relatives are valuable resources for the restoration of disease-resistance loci. However, available resistance loci in wild grape genomes remain largely unexplored. In this study, we assembled two phased genomes, including a high-resistant Chinese wild grape, Vitis davidii F & ouml;ex, and a susceptible cultivar, Vitis vinifera L. cv. 'Manicure Finger'. We detected a total of 36 688 structural variations (SVs), with the genes associated with heterozygous SVs showing an enrichment in allele-specific expression (ASE). Furthermore, we identified eight subgroups of R genes and found that 74.2% of R genes overlap with transposable elements (TEs). Among R genes, NBS-type genes exhibit higher expression profiles in the wild grape genome compared with those in the grape cultivar. Additionally, five specific NBS-type R gene clusters were identified in the wild grape genome that are absent in the cultivar. Through genetic mapping, we identified four quantitative trait loci (QTLs) associated with grape white rot resistance based on the V. davidii genome, within which six NBS-type R genes exhibit differential expression between wild and cultivated grapes. Overall, our study revealed the landscape of resistance genes in grape genomes, providing valuable genetic resources for further breeding programs.

分类号：

  • 相关文献

[1]Haplotype-resolved genome assembly of Corydalis yanhusuo, a traditional Chinese medicine with unusual telomere motif. Dingqiao Xu,Ziqi Ye,Yongji Huang,Kejin Zhu,Hongbo Xu,Jingao Yu,Yimeng Feng,Xinyue Zhao,Long Wang,Hao Xu,Qien Li,Minjian Qin,Yuping Tang,Xingtan Zhang,Yucheng Zhao. 2024

[2]Genomes of autotetraploid wild and cultivated Ziziphus mauritiana reveal polyploid evolution and crop domestication. Guo, Mingxin,Bi, Guiqi,Wang, Huan,Ren, Hui,Chen, Jiaying,Lian, Qun,Wang, Xiaomei,Fang, Weikuan,Zhang, Jiangjiang,Dong, Zhaonian,Pang, Yi,Zhang, Quanling,Huang, Sanwen,Yan, Jianbin,Zhao, Xusheng. 2024

[3]Analyzes of pan-genome and resequencing atlas unveil the genetic basis of jujube domestication. Mingxin Guo,Qun Lian,Ye Mei,Wangwang Yang,Suna Zhao,Siyuan Zhang,Xinfeng Xing,Haixiang Zhang,Keying Gao,Wentong He,Zhitong Wang,Huan Wang,Jun Zhou,Lin Cheng,Zhigui Bao,Sanwen Huang,Jianbin Yan,Xusheng Zhao. 2024

[4]A haplotype‐resolved genome for Rhododendron × pulchrum and the expression analysis of heat shock genes. Jian‐Shuang Shen1† , Lan Lan2,3,4† * , Sheng‐Long Kan2,4, He‐Feng Cheng1 , Dan Peng2 , Zi‐Yun Wan1 , Yue Hu1 , Xiao‐Ling Huang1 , Xue‐Qin Li1 , Yuan‐Jun Ye5 , Luke R. Tembrock6 , Zhi‐Qiang Wu2,4* , and Song‐Heng Jin1,7. 2024

[5]Recessive epistasis of a synonymous mutation confers cucumber domestication through epitranscriptomic regulation. Xin, Tongxu,Zhang, Zhen,Zhang, Yueying,Li, Xutong,Wang, Shenhao,Wang, Guanqun,Li, Haoxuan,Wang, Bowen,Zhang, Mengzhuo,Li, Wenjing,Tian, Haojie,Zhang, Zhonghua,Xiao, Yu-Lan,Tang, Weixin,He, Chuan,Ding, Yiliang,Huang, Sanwen,Yang, Xueyong. 2025

作者其他论文 更多>>