数字农科院2.0

Identification and characterization of a plasmid co-harboring blaCTX-M-55 and blaTEM-141 in Escherichia albertii from broiler in China

文献类型: 外文期刊

作者: Weiqi Guo;Di Wang;Xinyu Wang;Zhiyang Wang;Hong Zhu;Jiangang Hu;Beibei Zhang;Jingjing Qi;Mingxing Tian;Yanqing Bao;Na Li;Wanjiang Zhang;Shaohui Wang

作者机构:

关键词: antimicrobial resistance;Escherichia albertii;plasmid;whole genome sequencing

期刊名称: Journal of Integrative Agriculture

ISSN: 2095-3119

年卷期: 2025 年 24 卷 8 期

页码:

收录情况: SCIE(2025版) ; ; CSCD(2025-2026年度) ; ; 科技核心(2024版) ; ; 农林核心(2024版)

摘要: The inappropriate use of cephalosporins lead to the occurrence and global spread of bacteria resistant to these antimicrobials. In this study, we isolated four Escherichia albertii strains from broilers in eastern China. The antimicrobial susceptibility and genomic characterization of these E. albertii isolates were determined. Our results revealed that these four E. albertii isolates exhibited resistance to tetracyclines, chloramphenicol, β-lactams, aminoglycosides, polymyxin B, sulfonamides, quinolones, and other antimicrobials. Among them, EA04 isolate was multidrug resistant and harbored extended-spectrum β-lactamases (ESBL) genes blaCTX-M and blaTEM. Whole genome sequencing and core-genome multilocus sequence typing (cgMLST) based on all ST4638 E. albertii for EA04 inferred highly probable epidemiological links between selected human isolates. Additionally, the ESBL genes blaTEM-141 and blaCTX-M-55 were coexistent in an approximately 75 kb IncFII plasmid pEA04.2 in EA04. Comparative analysis indicated that genes blaTEM-141 and blaCTX-M-55 were located in IS15-blaCTX-M-55-wbuC-blaTEM-141-IS26 region, which similar structures were identified in various bacteria. Furthermore, the plasmid pEA04.2 could be transferable to E. coli EC600 and lead to the resistance to third-generation cephalosporins. These results suggested that chicken potentially serve as a reservoir for multidrug resistant E. albertii, which increases the risk of horizontal transfer of antimicrobial resistance between humans, animals and environment.

分类号:

  • 相关文献

[1]Multidrug resistance genes in staphylococci from animals that confer resistance to critically and highly important antimicrobial agents in human medicine. Wendlandt, Sarah,Kadlec, Kristina,Fessler, Andrea T.,Schwarz, Stefan,Shen, Jianzhong,Wang, Yang,Wu, Congming,Li, Beibei,Zhang, Wan-Jiang.

[2]Prevalent and Drug-Resistant Phenotypes and Genotypes of Escherichia coli Isolated from Healthy Cow’s Milk of Large-Scale Dairy Farms in China. Jiaojiao Gao,Yating Wu,Xianlan Ma,Xiaowei Xu,Aliya Tuerdi,Wei Shao,Nan Zheng,Yankun Zhao. 2025

[3]Nickel-resistant determinant from Leptospirillum ferriphilum. Tian, Jian,Wu, Ningfeng,Li, Jiang,Liu, Yajie,Guo, Jun,Yao, Bin,Fan, Yunliu.

[4]The technology of large-scale pharmaceutical plasmid purification by cetyltrimethylammonium bromide and Tritonx-114. Hou, S. H.,Zhu, H. F.,Zhang, Q.,Yuan, W. F.,Sun, H. C.. 2010

[5]Characterization of a blaCTX-M-3, blaKPC-2 and blaTEM-1B co-producing IncN plasmid in Escherichia coli of chicken origin. WANG W.-J.,WANG Y.-F.,JIN Y.-J.,SONG W.-Q.,LIN J.-M.,ZHANG Y.,TONG X.-R.,TU J.,LI R.-C.,LI T.. 2023

[6]Integrative and conjugative elements in streptococci can act as vectors for plasmids and translocatable units integrated via IS1216E. Qin Yang,Yao Zhu,Stefan Schwarz,Lingli Wang,Wenyu Liu,Wenlin Yang,Siguo Liu,Wanjiang Zhang. 2023

[7]Mobile Oxazolidinone Resistance Genes in Gram-Positive and Gram-Negative Bacteria. Stefan Schwarz,Wanjiang Zhang,Xiang Dang Du,Henrike Krüger,Andrea T. Feßler,Shizhen Ma,Yao Zhu,Congming Wu,Jianzhong Shen,Yang Wang. 2021

[8]Plasmid-mediated modulation of Listeria monocytogenes biofilm formation via TCS/PTS signaling: Implications for food contamination control. Jing Wang,Hui Min David Wang,Yang Qu,Ting Lin,Changyan Zhou,Zijie Lin,Yangtai Liu,Zhuosi Li,Qingli Dong,Yujuan Suo. 2026

[9]A detailed analysis of the recombination landscape of the button mushroom Agaricus bisporus var. bisporus. Sonnenberg, Anton S. M.,Gao, Wei,Lavrijssen, Brian,Hendrickx, Patrick,Sedaghat-Tellgerd, Narges,Baars, Johan J. P.,Visser, Richard G. F.,Foulongne-Oriol, Marie,Kong, Won-Sik,Schijlen, Elio G. W. M.,Gao, Wei.

[10]Comparative genomic analysis of the IId subtype family of Cryptosporidium parvum. Feng, Yaoyu,Li, Na,Feng, Yaoyu,Liu, Guangyuan,Li, Na,Roellig, Dawn M.,Kelley, Alyssa,Amer, Said,Xiao, Lihua,Amer, Said,Xiao, Lihua,Zhang, Longxian.

[11]Latest Advances in Watermelon Genomics. Guo, Shaogui,Xu, Yong,Zhang, Haiying,Gong, Guoyi,Guo, Shaogui,Zheng, Yi,Fei, Zhangjun,Huang, Sanwen,Yi, Hongping,Wu, Mingzhu,Fei, Zhangjun,Zheng, Yi. 2010

[12]Identification of Genomic Insertion and Flanking Sequence of G2-EPSPS and GAT Transgenes in Soybean Using Whole Genome Sequencing Method. Bingfu Guo,Yong Guo,Huilong Hong,Li-Juan Qiu. 2016

[13]In Vitro Probiotic Characteristics and Whole Genome Sequence Analysis of Lactobacillus Strains Isolated from Cattle-Yak Milk. Juanshan Zheng,Mei Du,Wei Jiang,Jianbo Zhang,Wenxiang Shen,Xiaoyu Ma,Zeyi Liang,Jiahao Shen,Xiaohu Wu,Xuezhi Ding. 2022

[14]Genetic characteristics and pathogenicity of the first bluetongue virus serotype 20 strain isolated in China. Qi, Yinglin,Wang, Fang,Chang, JiTao,Jiang, Zhigang,Sun, Chao,Lin, Jun,Wu, Jianmin,Yu, Li. 2022

[15]Population genomic analysis provides evidence of the past success and future potential of South China tiger captive conservation. Chen Wang,Dong Dong Wu,Yao Hua Yuan,Meng Cheng Yao,Jian Lin Han,Ya Jiang Wu,Fen Shan,Wan Ping Li,Jun Qiong Zhai,Mian Huang,Shi Ming Peng,Qin Hui Cai,Jian Yi Yu,Qun Xiu Liu,Zhao Yang Liu,Lin Xiang Li,Ming Sheng Teng,Wei Huang,Jun Ying Zhou,Chi Zhang,Wu Chen,Xiao Long Tu. 2023

[16]Two mutations at KRT74 and EDAR synergistically drive the fine-wool production in Chinese sheep. Liang, Benmeng,Bai, Tianyou,Zhao, Yuhetian,Han, Jiangang,He, Xiaohong,Pu, Yabin,Wang, Chunxin,Liu, Wujun,Ma, Qing,Tian, Kechuan,Zheng, Wenxin,Liu, Nan,Liu, Jianfeng,Ma, Yuehui,Jiang, Lin. 2024

[17]Genetic identification and expression optimization of a novel protease HapR from Bacillus velezensis. Zhenying Han,Changwen Ye,Xinyu Dong,Chenchen Chen,Dian Zou,Kuo Huang,Xuetuan Wei. 2024

[18]Xenorhabdus bovienii subsp. africana subsp. nov., isolated from Steinernema africanum entomopathogenic nematodes. Ricardo A.R. Machado,Aashaq H. Bhat,Patrick Fallet,Ted C.J. Turlings,Joelle Kajuga,Xun Yan,Stefan Toepfer. 2023

[19]Complete genome sequence provides information on quorum sensing related spoilage and virulence of Aeromonas salmonicida GMT3 isolated from spoiled sturgeon. Lei Liu,Jun Li,Mingxia Tu,Liang Gao,Ying Zhang,Yu Rao,Lei Rao,Meng Gui. 2024

[20]Genomic Characterization of Extended-Spectrum β-Lactamase (ESBL) Producing E. coli Harboring blaOXA-1-catB3-arr-3 Genes Isolated From Dairy Farm Environment in China. Shoaib, Muhammad,Tang, Minjia,Awan, Furqan,Aqib, Amjad Islam,Hao, Ruochen,Ahmad, Saad,Wang, Shengyi,Shang, Ruofeng,Pu, Wanxia. 2024

作者其他论文 更多>>