数字农科院2.0

Comparative analysis of the genes UL1 through UL7 of the duck enteritis virus and other herpesviruses of the subfamily Alphaherpesvirinae

文献类型： 外文期刊

作者： Li, Huixin;Liu, Shengwang;Han, Zongxi;Shao, Yuhao;Chen, Shuhong;Kong, Xiangang

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关键词： Duck enteritis virus;Phylogenetic analysis;UL1-UL7 genes

期刊名称： GENETICS AND MOLECULAR BIOLOGY

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收录情况： SCI

摘要： The nucleotide sequences of eight open reading frames (ORFs) located at the 5′ end of the unique long region of the duck enteritis virus (DEV) Clone-03 strain were determined. The genes identified were designated UL1, UL2, UL3, UL4, UL5, UL6 and UL7 homologues of the herpes simplex virus 1 (HSV-1). The DEV UL3.5 located between UL3 and UL4 had no homologue in the HSV-1. The arrangement and transcription orientation of the eight genes were collinear with their homologues in the HSV-1. Phylogenetic trees were constructed based on the alignments of the deduced amino acids of eight proteins with their homologues in 12 alpha-herpesviruses. In the UL1, UL3, UL3.5, UL5 and UL7 proteins trees, the branches were more closely related to the genus Mardivirus. However, the UL2, UL4, and UL6 proteins phylogenetic trees indicated a large distance from Mardivirus, indicating that the DEV evolved differently from other viruses in the subfamily Alphaherpesvirinae and formed a single branch within this subfamily.

分类号： Q3

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