数字农科院2.0

Genome-wide association study discovers new QTL and candidate genes on SSC2 associated with total teat number in Large White × Tongcheng crossbred pigs

文献类型： 外文期刊

作者： Qinghua Yang;Fang Ma;Jiao Yuan;Qiaoli Zhang;Zhiyi Chen;Yang Shen;Xiangge Meng;Songyu Li;Zining Yuan;Ping Zhou;Bang Liu;Xiang Zhou

作者机构：

关键词： （0-1-4）GWAS;QTL;SSC2;Tongcheng pig;total teat number

期刊名称： Animal Genetics

ISSN： 0268-9146

年卷期： 2025 年 56 卷 4 期

页码：

收录情况： SCIE（2025版）

摘要： Teat number is an economically important trait in pigs because it is relevant to reproduction efficiency and thus production profitability. In this study, a genome-wide association study (GWAS) was performed with genotyping by genome resequencing, which identified six significant SNPs (single nucleotide polymorphisms) on Sus scrofa chromosome 2 (SSC2) and SSC7 for total teat number using 888 Large White × Tongcheng crossbred pigs. The Bayesian fine-mapping further defined two QTL (quantitative trait loci) with locations of 18.32–19.08 and 21.18–22.11 Mb on SSC2, and one QTL spanned an interval of 97.14–97.91 Mb on SSC7, respectively. The first SSC2 QTL region harbors four candidate genes TTC17, API5, miR-129-2 and HSD17B12. The SSC7 QTL region include two reported candidate genes, VRTN and ABCD4. The average teat numbers are 12.42 ± 1.38, 13.52 ± 1.10 and 13.87 ± 1.03 for TT, TA and AA genotypes of rs340400902 on SSC2, respectively. The T allele of rs340400902 on SSC2 in Large White × Tongcheng crossbred pigs was found to originate from Tongcheng pigs. These findings provides SNPs and candidate genes for the genetic improvement of teat number in pigs.

分类号：

  • 相关文献

[1]Genotyping by sequencing reveals a new locus for pig teat number. Wang, L.,Zhang, Y.,Zhang, T.,Zhang, L.,Yan, H.,Liu, X.,Wang, L..

[2]CIMMYT小麦种质C615抗叶锈病QTL分析. 李玉玲,蒋正宁,胡文静,李东升,程婧晔,裔新,程晓明,吴荣林,程顺和. 2018

[3]油菜开花期QTL定位和候选基因分析. 魏雅琪,危文亮,刘道敏,张江江,詹杰鹏,师家勤,王新发,刘贵华. 2019

[4]水稻白叶枯病抗性基因定位及其小种专化性. 罗利军,梅捍卫,赵新华,钟代彬,王一平,余新桥,应存山,Li Zhikang,Paterson A H,Wang Daolong,Tabien R,Zhu L,Stansel J W. 1998

[5]油菜株高QTL定位、整合和候选基因鉴定. 张江江,詹杰鹏,刘清云,师家勤,王新发,刘贵华,王汉中. 2017

[6]棉花重组自交系铃重性状的QTL定位. 曲朝阳,贾晓昀,马启峰,王寒涛,魏恒玲,范术丽. 2019

[7]甜菜根产量和含糖率性状的QTL定位. 王茂芊,李博,吴则东,王华忠. 2017

[8]水稻白叶枯病抗性基因定位及其小种专化性. 罗利军,梅捍卫,赵新华,钟代彬,王一平,余新桥,应存山,ZhikangLi,A.H.Paterson,DaolongWang,R.Tabien,L.Zhu,J.W.Stansel. 1998

[9]基于CSSL的高密度物理图谱定位水稻分蘖角度QTL. 周丽慧,于新,赵庆勇,陈涛,姚姝,张亚东,朱镇,王才林. 2012

[10]利用籼粳交“热粳35/协B”F_2群体对水稻再生力的QTL分析. 李兴星,郑剑,周军杰,杨永清,秦小健,张汉马,梁永书. 2016

[11]利用水稻重组自交系群体材料和特征次生物质标记法定位水稻化感基因. 周勇军,曹长代,郑康乐,郭怡青,叶敏,余柳青. 2006

[12]水稻苗期耐低氮相关性状的QTL定位. 赵凌,张亚东,陈涛,赵庆勇,朱镇,周丽慧,姚姝,王才林. 2015

[13]利用染色体单片段置换系对水稻芒性状的4个QTLs进行定位分析. 朱文银,张亚东,朱镇,赵凌,陈涛,赵庆勇,周丽慧,方先文,王艳平,王才林. 2010

[14]超级稻协优9308根系相关性状QTLs的精细定位. 王会民. 2013

[15]水稻化感材料控制稗草的基因定位研究. 徐正浩,何勇,崔绍荣,赵明,张旭,李迪. 2003

[16]水稻低温冷害分析研究进展. 聂元元,蔡耀辉,颜满莲,李永辉,毛凌华,颜龙安,杨晓莉. 2011

[17]TD70/Kasalath RIL群体定位水稻花药基部开裂长度QTL（英文）. 赵凌,张亚东,赵春芳,周丽慧,姚姝,于新,丁丹,Tsutomu MATSUI,王才林. 2015

[18]小麦“N553×扬麦13”RIL群体小穗密度、株高及赤霉病抗性QTL分析. 孙阳阳,张勇,胡文静,陈树林,刘健,李东升,程凯,程婧晔,程晓明,程顺和. 2017

[19]水稻第6染色体短臂上独立于抽穗期变异的产量性状QTL. 樊叶杨,陈忱,吴季荣,程式华,庄杰云. 2010

[20]水稻产量性状杂种优势的QTL定位. 陈深广,沈希宏,曹立勇,占小登,冯跃,吴伟明,程式华. 2010

作者其他论文 更多>>