数字农科院2.0

Early life imidacloprid and copper exposure affects the gut microbiome, metabolism, and learning ability of honey bees (Apis mellifera)

文献类型： 外文期刊

作者： Xijie Li;Qihe Tang;Mengshang Hou;Yantao Pang;Dan Li;Yajuan Chen;Richan Fang;Yi Deng;Jun Zhang;Chonghui Zhao;Junjie Li;Yuan Chen;Yazhou Zhao;Jun Guo;Kai Qian

作者机构：

关键词： Apis mellifera;Copper;Gut microbiota;Imidacloprid;Learning ability;Non-targeted metabolomics

期刊名称： Environmental Research

ISSN： 0013-9351

年卷期： 2025 年 273 卷

页码：

收录情况： SCIE（2025版） ; ; EI（2025版）

摘要： The pesticide imidacloprid and the heavy metal copper provide some degree of protection to plants, while at the same time causing varying degrees of damage to bees. However, few studies have investigated the negative effects of imidacloprid and copper exposure on newly emerged bees (young bees), especially when both are present in a mix. In this study, young bees were exposed to sterile sucrose solutions containing imidacloprid (10 μg/L, 100 μg/L), copper (10 mg/L, 50 mg/L), or a mix of both (10 μg/L + 10 mg/L) for 5 days to assess their gut system and behavior, with survival and dietary consumption recorded over 21 days. We found that imidacloprid and copper reduced honeybee survival, dietary intake, and learning ability, decreased gut microbiota diversity, and caused metabolic disruptions. Notably, the mix of imidacloprid and copper had a synergistic negative effect. Correlation analyses revealed that the honeybee gut microbiota influences bee immunity and behavior by regulating metabolic pathways related to ascorbate, tryptophan, and carbohydrates. Our results demonstrate that imidacloprid and copper, either alone or in a mix, alter young bee health through a complex mechanism of toxicity. These findings highlight imidacloprid and copper's negative effects on young honeybees, offering insights for future pesticide and heavy metal impact research.

分类号：

  • 相关文献

[1]Bt Toxin Cry1Ie Causes No Negative Effects on Survival, Pollen Consumption, or Olfactory Learning in Worker Honey Bees (Hymenoptera: Apidae). Diao, Qing-Yun,Jia, Hui-Ru,Geng, Li-Li.

[2]Monitoring honeybee colonies under imidacloprid exposure based on smart beehive system. Lu, Yuntao,Yan, Yinfa,Liu, Zhenguo,Wang, Ying,Wang, Hongfang,Chi, Xuepeng,Yan, Xiangting,Xu, Baohua,Hong, Wei,Liu, Shengping. 2025

[3]A new cage design to test pesticide impacts on honey bees via toxicant exposure through sucrose, pollen and beeswax simultaneously. Cameron J. Jack,Cody Prouty,Gerbson A. Mendonça,Ping Li Dai,Jeffrey R. Bloomquist,James D. Ellis. 2025

[4]A new strategy to alleviate the obesity induced by endocrine disruptors—A unique lysine metabolic pathway of nanoselenium Siraitia grosvenorii to repair gut microbiota and resist obesity. Yu Wang,Wei Sun,Sen Yan,Zhiyuan Meng,Ming Jia,Sinuo Tian,Shiran Huang,Xiaoxuan Sun,Shihang Han,Canping Pan,Jinling Diao,Qiuxia Wang,Wentao Zhu. 2023

[5]Varroa destructor infestation amplifies imidacloprid vulnerability in Apis mellifera. Yinchen Wang,Xijie Li,Chunhui Miao,Chonghui Zhao,Jun Zhang,Yantao Pang,Junjie Li,Richan Fang,Xueyi Shen,Ying Lin,Tian Zhao,Mengqing Deng,Luansong Zhang,Hua Wang,Wanli Li,Jun Guo. 2025

[6]Honeybee (Apis mellifera) resistance to deltamethrin exposure by Modulating the gut microbiota and improving immunity. Zhi Xiang Dong,Qi He Tang,Wan L.I. Li,Zheng Wei Wang,Xi Jie Li,Chao Min Fu,Dan Li,Kai Qian,Wen L.I. Tian,Jun Guo. 2022

[7]Genetic divergence and functional convergence of gut bacteria between the Eastern honey bee Apis cerana and the Western honey bee Apis mellifera. Yuqi Wu,Yufei Zheng,Shuai Wang,Yanping Chen,Junyi Tao,Yanan Chen,Gongwen Chen,Hongxia Zhao,Kai Wang,Kun Dong,Fuliang Hu,Ye Feng,Huoqing Zheng. 2022

[8]Interactive effects of dinotefuran and Nosema ceranae on the survival status and gut microbial community of honey bees. Linlin Liu,Min Shi,Yanyan Wu,Xianbing Xie,Shanshan Li,Pingli Dai,Jing Gao. 2024

[9]Improving bee feed recipes to safeguard honeybee colonies during times of food scarcity. Xue Wang,Xing Zheng,Nana Guo,Mingyang Geng,Rongshen Wang,Ting Huang,Quanzhi Ji,Zhenxing Liu,Yazhou Zhao. 2024

[10]Organic Acid Supplementation in Worker Honeybees (Apis mellifera): Impacts on Glandular Physiology and Colony Resilience. Gebreamlak Bezabih,Tesfay Atsbha,Solomon Zewdu Altaye,Qingsong Zhou,Jianke Li,Christian W.W. Pirk,Chaodong Zhu,Yu Fang. 2025

[11]Integration of hyperspectral imaging, non-targeted metabolomics and machine learning for vigour prediction of naturally and accelerated aged sweetcorn seeds. Tingting Zhang,Long Lu,Ni Yang,Ian D. Fisk,Wensong Wei,Li Wang,Jing Li,Qun Sun,Rensen Zeng. 2023

[12]Profiling of dynamic changes in non-volatile metabolites of shaken black tea during the manufacturing process using targeted and non-targeted metabolomics analysis. Jinjin Xue,Panpan Liu,Guiyi Guo,Weiwei Wang,Jianyong Zhang,Wei Wang,Ting Le,Junfeng Yin,Dejiang Ni,Heyuan Jiang. 2022

[13]Identification of markers for tea authenticity assessment: Non-targeted metabolomics of highly similar oolong tea cultivars (Camellia sinensis var. sinensis). Jie Zhao,Wenwen Liu,Yan Chen,Xin Zhang,Xu Wang,Fuhua Wang,Yongzhong Qian,Jing Qiu. 2022

[14]Changes in postmortem metabolites profile of atypical and typical DFD beef. Ijaz M.,Zhang D.,Hou C.,Mahmood M.,Hussain Z.,Zheng X.,Li X.. 2022

[15]Bacterial community response in ginseng rhizosphere soil after Pseudomonas P1 inoculation integrating intracellular non-targeted metabolomics analysis. Sun H.,Shao C.,Liang H.,Qian J.,Jin Q.,Zhu J.,Zhang G.,Lv B.,Zhang Y.. 2024

[16]Effect of Sex on Intestinal Microbial Metabolites of Hainan Special Wild Boars. Xiaozhe Wang,Qiong Wen,Hongfen Wu,Wenchuan Peng,Keqi Cai,Zhen Tan,Wei Na,Kebang Wu. 2024

[17]DFT-guided design of biochar-based composites for photocatalytic degradation of fluoroquinolone antibiotics in soil-water systems: Non-targeted metabolomics and structural equation modeling. Qilan Huang,Qianru Zhang,Shuwen Zhao,Xiaoming Chen,Huixin Guan,Jianqiao Liu. 2025

[18]Phosphatidic Acid Homeostasis and Membrane Lipid Remodeling Confer Salt Tolerance in Zoysia japonica by Stabilizing Metabolic Networks and a Putative SOS Signaling Activation. Qinhao Yang,Xiangcui Zeng,Zhenzhen Liu,Zhongkuan Liu,Qiannan Hu,Mingna Li. 2025

[19]Biochemical mechanisms of imidacloprid resistance in Nilaparvata lugens: Over-expression of cytochrome P450 CYP6AY1. Ding, Zhiping,Wen, Yucong,Zhang, Yixi,Liu, Zewen,Han, Zhaojun,Yang, Baojun,Liu, Shuhua.

[20]E-beta-farnesene synergizes the influence of an insecticide to improve control of cabbage aphids in China. Dong, Jie,Liu, Ying-Jie,Liu, Yong,Heuskin, Stephanie,Lognay, Georges,Chen, Ju-Lian,Bragard, Claude,Tooker, John F.. 2012

作者其他论文 更多>>