数字农科院2.0

Whole-Transcriptome Rna Sequencing Reveals The Global Molecular Responses And Cerna Regulatory Network Of Mrnas, Lncrnas, Mirnas And Circrnas In Response To Copper Toxicity In Ziyang Xiangcheng (Citrus Junos Sieb. Ex Tanaka)

文献类型： 外文期刊

作者： Zhang, Xiao-Yong;Fu, Xing-Zheng;Fu, Xing-Zheng;Yuan, Meng;He, Yi-Zhong;Qiu, Jie-Ya;Zhou, Xue;Ling, Li-Li;Peng, Liang-Zhi;Chun, Chang-Pin;Cao, Li;Qiu, Jie-Ya;Chun, Chang-Pin;Zhou, Xue;He, Yi-Zhong;Yuan, Meng;Peng, Liang-Zhi;Ling, Li-Li;Cao, Li;Zhang, Xiao-Yong;Fu, Xing-Zheng;Fu, Xing-Zheng

作者机构：

关键词： Citrus; Copper; Cerna; Transcriptome; Non-Coding Rna

期刊名称： BMC PLANT BIOLOGY

ISSN： 1471-2229

年卷期： 2019 年 19 卷 1 期

页码：

摘要： Background Copper (Cu) toxicity has become a potential threat for citrus production, but little is known about related mechanisms. This study aims to uncover the global landscape of mRNAs, long non-coding RNAs (lncRNAs), circular RNAs (circRNAs) and microRNAs (miRNAs) in response to Cu toxicity so as to construct a regulatory network of competing endogenous RNAs (ceRNAs) and to provide valuable knowledge pertinent to Cu response in citrus. Results Tolerance of four commonly used rootstocks to Cu toxicity was evaluated, and 'Ziyang Xiangcheng' (Citrus junos) was found to be the most tolerant genotype. Then the roots and leaves sampled from 'Ziyang Xiangcheng' with or without Cu treatment were used for whole-transcriptome sequencing. In total, 5734 and 222 mRNAs, 164 and 5 lncRNAs, 45 and 17 circRNAs, and 147 and 130 miRNAs were identified to be differentially expressed (DE) in Cu-treated roots and leaves, respectively, in comparison with the control. Gene ontology enrichment analysis showed that most of the DEmRNAs and targets of DElncRNAs and DEmiRNAs were annotated to the categories of 'oxidation-reduction', 'phosphorylation', 'membrane', and 'ion binding'. The ceRNA network was then constructed with the predicted pairs of DEmRNAs-DEmiRNAs and DElncRNAs-DEmiRNAs, which further revealed regulatory roles of these DERNAs in Cu toxicity. Conclusions A large number of mRNAs, lncRNAs, circRNAs, and miRNAs in 'Ziyang Xiangcheng' were altered in response to Cu toxicity, which may play crucial roles in mitigation of Cu toxicity through the ceRNA regulatory network in this Cu-tolerant rootstock.

分类号：

  • 相关文献

[1]Cooperative Application Of Transcriptomics And Cerna Hypothesis: Lncrna-107052630/Mir-205A/G0S2 Crosstalk Is Involved In Ammonia-Induced Intestinal Apoptotic Injury In Chicken. Wang, SC, Wang, W, Li, XJ, Zhao, X, Wang, Y, Zhang, HF, Xu, SW. 2020

[2]中国葡萄类病毒基因多样性分析及其新种的发现. 姜冬梅,郭瑞,彭山,吴祖建. 2009

[3]中国栽培葡萄上发生的类病毒的种类鉴定. 王晶,SanoTeruo. 2003

[4]Transcriptomic Analysis Of Long Non-Coding R.nas And Coding Genes U ncovers A Complex Regulatory Network That Is Involved In Maize Seed Development. Xu, Miaoyun,Wang, Lei,Zhu, Ming,Zhu, Ming,Zhang, Min,Jiang, Haiyang,Xing, Lijuan,Li, Wenzong. 2017

[5]Lncrna As Cernas May Be I.nvolved In Lactation Process. Yu, S, Zhao, Y, Lai, FN, Chu, MQ, Hao, YN, Feng, YN, Zhang, HF, Liu, J, Cheng, M, Li, L, Shen, W, Min, LJ. 2017

[6]Ammonia Regulates Chicken Tracheal Cell Necroptosis Via The Lncrna-107053293/Mir-148A-3P/Faf1 Axis. Wang, W, Shi, QX, Wang, SC, Zhang, HF, Xu, SW. 2020

[7]Circrna As Cerna Mediated By M.icrorna May Be Involved I n Goat Lactation. Ma, DX, Zhao, Y, Yu, S, Zhang, HF, Cheng, M, Cao, HF, Li, Q, Min, LJ. 2019

[8]Recent Advances In Understanding The R.ole Of Mirnas In E xosomes And Their Therapeutic Potential. Miao, XY. 2017

[9]Invasiondb: A Genome And Gene Database Of Invasive Alien Species. Huang, C, Lang, K, Qian, WQ, Wang, SP, Cao, XM, He, R, Zhan, AR, Chen, MY, Yang, NW, Li, F. 2021

[10]Present Scenario Of Circular Rnas (.Circrnas) In Plants. Zhao, W, Chu, SS, Jiao, YQ. 2019

[11]Role of microRNA and long non-coding RNA in Marek's disease tumorigenesis in chicken. Zhaobo Zhang,Sishi Zhang,Guoshuai Wang,Siyu Feng,Kexin Han,Limei Han,Liping Han. 2021

[12]Dietary Copper Reduces The Hepatotoxicity O.f (-)-Epigallocatechin-3-Gallate In Mice. Wang, Le,Chen, Xuan,Kaleri, Najeeb Ahmed,Zhang, Wenzheng,Li, Xinghui,Li, Jin,Sun, Kang. 2018

[13]Synergistic Effects Of Chromium And C.opper On Photosynthetic Inhibition, S ubcellular Distribution, And Related Gene Expression In Brassica Napus Cultivars. Zhou, Weijun,Islam, Faisal,Long, Meijuan,Wang, Jian,Shou, Jianyao,Li, Lan,Mwamba, Theodore M.,Farooq, Muhammad A.. 2019

[14]Rice Heavy Metal P-Type Atpase Oshma6 Is Likely A Copper Efflux Protein. Chen Jingguang,Ye Guoyou,Li Chang,Zhu Yajun,Zou Wenli,He Haohua,Zou Wenli. 2020

[15]Adsorption Properties Of Nano-Mno2-Biochar Composites F.or Copper In Aqueous S olution. Zhou, L, Huang, YF, Qiu, WW, Sun, ZX, Liu, ZQ, Song, ZG. 2017

[16]Modeling For Predicting Copper Ion R.emoval From Aqueous Solution B y The Fluidized Adsorption Based On Dimensional Analysis. Du, ZL, Cao, HZ, Liu, GD, Zheng, T, Wang, P, Quan, J. 2019

[17]Induction Of Copper And Iron I.n Acute Cold-Stimulated Brown A dipose Tissues. Wang, C, Liang, XJ, Tao, C, Yao, XL, Wang, YJ, Wang, YF, Li, K. 2017

[18]Suppressive Effects Of Thermal-Treated Oyster S.hells On Cadmium And C opper Translocation In Maize Plants. Wang, CY, Alidoust, D, Isoda, A, Li, MS. 2017

[19]Adipocyte-Specific Disruption Of Atpase Copper Transporting Alpha In Mice Accelerates Lipoatrophy. Tao, C, Wang, YJ, Zhao, Y, Pan, JF, Fan, YP, Liang, XJ, Cao, CW, Zhao, JG, Petris, MJ, Li, K, Wang, YF. 2019

[20]Prediction Of Soil Copper Phytotoxicity To Barley Root Elongation By An Edta Extraction Method. Jiang, B, Ma, YB, Zhu, GY, Li, J. 2020

作者其他论文 更多>>