数字农科院2.0

Anti-Phytopathogenic Bacterial Metabolites From The Seaweed-Derived Fungus Aspergillus Sp. D40

文献类型： 外文期刊

作者： Huang, RH; Lin, W; Zhang, P; Liu, JY; Wang, D; Li, YQ; Li, W; Zhao, DL; Wang, XQ; Zhang, CS

作者机构：

关键词： Furanones; Penicillic Acid; Ralstonia Solanacearum; Phytopathogenic Bacteria; Antibacterial Activity

期刊名称： FRONTIERS IN MARINE SCIENCE

ISSN：

年卷期： 2020 年 7 卷

页码：

收录情况： JCR（2021版）

摘要： In order to search for new lead compounds with anti-phytopathogenic bacterial activity, three pairs of new furanone derivatives, sclerotiorumins D-F (1-3), and eight known compounds (4-11) were isolated from the seaweed-derived fungus, Aspergillus sp. D40, fermented with potato dextrose seawater (PDW) medium. Their structures were determined using comprehensive spectroscopic analyzes including HRESIMS, 1D and 2D NMR data. Compounds 1-4 and 9 existed as inseparable mixtures of a pair of epimers. Penicillic acid (7) exhibited clear antibacterial activity against Ralstonia solanacearum and several other plant pathogenic bacteria with IC50 values ranging from 11.6 to 58.2 mu g/mL.

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