数字农科院2.0

Longitudinal Investigation Of The Gut Microbiota In Goat Kids From Birth To Postweaning

文献类型： 外文期刊

作者： Zhuang, YM; Chai, JM; Cui, K; Bi, YL; Diao, QY; Huang, WQ; Usdrowski, H; Zhang, NF

作者机构：

关键词： Gut Microbiota; Goat; Ruminants; Ages; Biogeography; Temporal Dynamics

期刊名称： MICROORGANISMS

ISSN：

年卷期： 2020 年 8 卷 8 期

页码：

收录情况： JCR（2021版）

摘要： Early microbial colonization in the gut impacts animal performance and lifelong health. However, research on gut microbial colonization and development in young ruminants, especially after weaning, is currently limited. In this study, next-generation sequencing technology was performed to investigate the temporal dynamic changes of the microbial community in the jejunum and colon of goats at 1, 7, 14, 28, 42, 56, 70, and 84 days (d) of age. As age increased, significant increases in microbial diversity, including the number of Observed OTUs and the Shannon Index, were observed in both the jejunum and colon. Regarding beta diversity, significant shifts in community membership and structure from d1 to d84 were observed based on both Bray-Curtis and Jaccard distances. With increasing age, dominant genera in the jejunum shifted fromLactobacillusto unclassifiedRuminococcaceae, unclassifiedLachnospiraceaeand unclassifiedClostridialesthrough starter supplementation, whereas colonic dominant genera changed fromLactobacillusandButyricicoccus, within d1-d28, to unclassifiedRuminococcaceae, unclassifiedClostridialesandCampylobacterafter solid diet supplementation. The linear discriminant analysis (LDA) effect size (LEfSe) analysis revealed bacterial features that are stage-specific in the jejunum and colon, respectively. In the jejunum and colon, a significantly distinct structure and membership of the microbiota was observed across all ages. The growth stage-associated microbiota in each gut compartment was also identified as a marker for biogeography. Our data indicate the temporal and spatial differences of the gut microbiota in goats are important for their performance and health. Early microbial colonization can influence microbial composition in later life (e.g., post-weaning phase). This study provides insights that the temporal dynamics of gut microbiota development from newborn to post-weaning can aid in developing feeding strategies to improve goat health and production.

分类号：

  • 相关文献

[1]Tea Polypeptide Ameliorates Diabetic Nephropathy T.hrough Rage And Nf-Kappa B Signaling Pathway In Type 2 Diabetes Mice. Sun, Lingli,Deng, Xuming,Lai, Xingfei,Li, Qiuhua,Deng, Xuming,Sun, Shili,Xiang, Limin,Zhang, Wenji,Zhang, Lingzhi. 2018

[2]A Review Of Enteric Methane Emission Measurement Techniques In Ruminants. Zhao, YG, Nan, XM, Yang, L, Zheng, SS, Jiang, LS, Xiong, BH. 2020

[3]Long‐term biochar application promotes rice productivity by regulating root dynamic development and reducing nitrogen leaching. Bitao Liu,Hongliang Li,Hongbo Li,Aiping Zhang,Zed Rengel. 2020

[4]Complete genome analysis reveals evolutionary history and temporal dynamics of Marek’s disease virus. Kai Li,Zhenghao Yu,Xingge Lan,Yanan Wang,Xiaole Qi,Hongyu Cui,Li Gao,Xiaomei Wang,Yanping Zhang,Yulong Gao,Changjun Liu. 2022

[5]Analysis Of 22 Elements In M.ilk, Feed, And Water O f Dairy Cow, Goat, And Buffalo From Different Regions Of China. Zhou, XW, Qu, XY, Zhao, SG, Wang, JQ, Li, SL, Zheng, N. 2017

[6]Identification Of Differentially Expressed Long N.oncoding Rnas And Mrnas I nvolved With Dominant Follicle Selection In Goats Using Rna-Seq. Guang-Xin, E, Zhao, YJ, Ma, YH, Chu, MX, Zhang, JH, Zhao, ZQ, Gao, HJ, Jiang, HZ, Liu, D, Liu, L, Zhu, YB, Basang, WD, Danjiu, LB, An, TW, Luo, XL, He, SC, Huang, YF. 2018

[7]Identification Of Lncrnas By Rna S.equencing Analysis During In V ivo Pre-Implantation Developmental Transformation In The Goat. Ling, YH, Zheng, Q, Li, YS, Sui, MH, Wu, H, Zhang, YH, Chu, MX, Ma, YH, Fang, FG, Xu, LN. 2019

[8]A Systematic Review And Meta-Analysis O.f Small Ruminant And P orcine Trypanosomiasis Prevalence In Sub-Saharan Africa (1986 To 2018). Ebhodaghe, F, Ohiolei, JA, Isaac, C. 2018

[9]Seasonal Dynamics Of Gastrointestinal Nematode I.nfections Of Goats And E mergence Of Ivermectin Resistance In Haemonchus Contortus In Hubei Province, China. Yuan, W, Lu, K, Li, H, Liu, JM, He, CC, Feng, JT, Zhang, X, Mao, YD, Hong, Y, Zhou, Y, Lu, J, Jin, YM, Lin, JJ. 2019

[10]A Recombinant Fasciola Gigantica 14-3-3 E.psilon Protein (Rfg14-3-3E) Modulates V arious Functions Of Goat Peripheral Blood Mononuclear Cells. Tian, AL, Lu, MM, Calderon-Mantilla, G, Petsalaki, E, Dottorini, T, Tian, XW, Wang, YJ, Huang, SY, Hou, JL, Li, XR, Elsheikha, HM, Zhu, XQ. 2018

[11]First Molecular Description, Phylogeny And G.enetic Variation Of Taenia H ydatigena From Nigerian Sheep And Goats Based On Three Mitochondrial Genes. Ohiolei, JA, Luka, J, Zhu, GQ, Yan, HB, Li, L, Magaji, AA, Alvi, MA, Wu, YT, Li, JQ, Fu, BQ, Jia, WZ. 2019

[12]Characterization Of Gonadotropin Releasing Hormone Receptor Gene In Sokoto And Kalahari Red Goats. Isa, AM, Bemji, MN, Wheto, M, Williams, TJ, Ibeagha-Awemu, EM. 2019

[13]In vitro Study of Urtica cannabina and Leymus chinensis on Rumen Microbial Fermentation and Gas Production. Zhang Z., Wang S., Qi R., Shahzad K., Shi L., Zhang X., Wang M.. 2022

[14]The excretory-secretory antigen HcADRM1 to generate protective immunity against Haemonchus contortus. Lu, Mingmin,Tian, Xiaowei,Wang, Wenjuan,Zhang, Yang,Aimulajiang, Kalibixiati,Tian, Ai-Ling,Li, Charles,Yan, Ruofeng,Xu, Lixin,Song, Xiaokai,Li, Xiangrui. 2021

[15]A deletion variant within the FGF5 gene in goats is associated with gene expression levels and cashmere growth. Li Y., Song S., Zhang Z., Liu X., Zhang Y., Guangxin E., Ma Y., Jiang L.. 2022

[16]Discrimination of mutton from different sources (regions, feeding patterns and species) by mineral elements in Inner Mongolia, China. Qian Wang,Haijin Liu,Shanshan Zhao,Mengjie Qie,Yang Bai,Jiukai Zhang,Jun Guo,Yan Zhao. 2021

[17]Characterization Of Haemonchus Contortus Excretory/Secretory Antigen (Es-15) And Its Modulatory Functions On Goat Immune Cells In Vitro. Ehsan, M, Gadahi, JA, Hasan, MW, Haseeb, M, Ali, H, Yan, RF, Xu, LX, Song, XK, Zhu, XQ, Li, XR. 2020

[18]Tropomyosin: An Excretory/Secretory Protein From Haemonchus Contortus Mediates The Immuno-Suppressive Potential Of Goat Peripheral Blood Mononuclear Cells In Vitro. Ehsan, M, Haseeb, M, Hu, RS, Ali, H, Memon, MA, Yan, RF, Xu, LX, Song, XK, Zhu, XQ, Li, XR. 2020

[19]Comprehensive Analysis Of Lncrna Reveals T.he Temporal-Specific Module Of G oat Skeletal Muscle Development. Ling, YH, Zheng, Q, Sui, MH, Zhu, L, Xu, LN, Zhang, YH, Liu, Y, Fang, FG, Chu, MX, Ma, YH, Zhang, XR. 2019

[20]Genetic Diversity Analysis Of Major S.ri Lankan Goat Populations U sing Microsatellite And Mitochondrial Dna D-Loop Variations. Silva, P, Dematawewa, CMB, Kurukulasuriya, M, Utsunomiya, YT, Garcia, JF, Pichler, R, Thiruvenkadan, AK, Ramasamy, S, Han, JL, Periasamy, K. 2017

作者其他论文 更多>>