数字农科院2.0

Seroprevalence and associated risk factors of Toxoplasma gondii infection in psychiatric patients: a case-control study in eastern China

文献类型： 外文期刊

作者： Cong, W.;Ni, X. -T.;Zhu, X. -Q.;Cong, W.;Qian, A. -D.;Dong, W.;Bai, L.;Wang, X. -Y.;Ni, X. -T.

作者机构：

关键词： Eastern China;psychiatric patients;seroepidemiology;Toxoplasma gondii;toxoplasmosis

期刊名称： EPIDEMIOLOGY AND INFECTION

ISSN： 0950-2688

年卷期： 2015 年 143 卷 14 期

页码：

收录情况： SCI

摘要： In recent years, the effect of Toxoplasma gondii infection on the cerebrum and neuropsychiatric patients has been increasingly highlighted. However, there is limited information about the epidemiology of T. gondii infection in psychiatric patients in Shandong province, eastern China. Therefore, through a case-control study, 445 patients hospitalized for diacrisis or treatment in Weihai, eastern China, and 445 control subjects from the general population of the same region matched by gender, age, and residence were examined with enzyme-linked immunoassays for the presence of IgG and IgM antibodies to T. gondii and associated sociodemographic and behavioural characteristics in a population of psychiatric patients. Seroprevalence of IgG antibodies to T. gondii in psychiatric patients (77/445, 17.30%) was significantly higher than in control subjects (55/445, 12.36%) (P = 0.038). Fourteen (3.15%) psychiatric patients and 10 (2.25%) control subjects had IgM antibodies to T. gondii (P = 0.408). Multivariate analysis using logic regression showed that T. gondii infection was associated with cats at home and consumption of raw/undercooked meat in psychiatric patients. Considering that most psychiatric patients usually have lower cognitive functioning and additional transmission routes related to their inappropriate behaviours that could enhance the risk of infection, psychiatric patients should be considered as a specific group of T. gondii infection.

分类号：

  • 相关文献

[1]Seroepidemiology of Toxoplasma gondii infection in Bai and Han ethnic groups in southwestern China. Li, H. -L.,Chen, J.,Zhu, X. -Q.,Li, H. -L.,Dong, L.,Li, Q.,Zhang, L.,Zhu, X. -Q.,Zou, F. -C.. 2015

[2]Prevalence and genotyping of Toxoplasma gondii in naturally-infected synanthropic rats (Rattus norvegicus) and mice (Mus musculus) in eastern China. Yan, Chao,Liang, Li-Jun,Zhang, Bei-Bei,Zhang, Hui-Feng,Shen, Xuan,Wu, Yu-Qing,Wang, Zi-Mu,Tang, Ren-Xian,Fu, Lin-Lin,Zheng, Kui-Yang,Liang, Li-Jun,Zhang, Hui-Feng,Shen, Xuan,Wang, Zi-Mu,Lou, Zhi-Long,Wu, Yu-Qing. 2014

[3]First Report of Toxoplasma gondii Seroprevalence in Pet Parrots in China. Zhang, Xiao-Xuan,Zhang, Nian-Zhang,Tian, Wei-Peng,Zhou, Dong-Hui,Zhu, Xing-Quan,Zhang, Xiao-Xuan,Xu, Ying-Tian,Tian, Wei-Peng. 2014

[4]Vaccination with Toxoplasma gondii calcium-dependent protein kinase 6 and rhoptry protein 18 encapsulated in poly(lactide-co-glycolide) microspheres induces long-term protective immunity in mice. Zhang, Nian-Zhang,Xu, Ying,Wang, Meng,Chen, Jia,Huang, Si-Yang,Zhu, Xing-Quan,Xu, Ying,Gao, Qi,Huang, Si-Yang,Zhu, Xing-Quan. 2016

[5]Evaluation of protective effect of pVAX-TgMIC13 plasmid against acute and chronic Toxoplasma gondii infection in a murine model. Yuan, Zi-Guo,Ren, Di,Zhou, Dong-Hui,Zhou, Yang,Zhu, Xing-Quan,Yuan, Zi-Guo,Ren, Di,Zhang, Xiu-Xiang,Li, Xiu-Zhen,Petersen, Eskild,Petersen, Eskild,Yang, Gui-Lian,Zhu, Xing-Quan. 2013

[6]Protective immunity against Toxoplasma gondii induced by DNA immunization with the gene encoding a novel vaccine candidate: calcium-dependent protein kinase 3. Zhang, Nian-Zhang,Huang, Si-Yang,Zhou, Dong-Hui,Chen, Jia,Zhu, Xing-Quan,Xu, Ying,Zhu, Xing-Quan,Tian, Wei-Peng,Lu, Jing,Zhu, Xing-Quan. 2013

[7]DNA vaccination with genes encoding Toxoplasma gondii antigens ROP5 and GRA15 induces protective immunity against toxoplasmosis in Kunming mice. Chen, Jia,Li, Zhong-Yuan,Huang, Si-Yang,Zhou, Dong-Hui,Zhu, Xing-Quan,Li, Zhong-Yuan,Zhu, Xing-Quan,Petersen, Eskild,Zhu, Xing-Quan. 2015

[8]DNA immunization with eukaryotic initiation factor-2 alpha of Toxoplasma gondii induces protective immunity against acute and chronic toxoplasmosis in mice. Chen, Jia,Huang, Si-Yang,Zhou, Dong-Hui,Li, Zhong-Yuan,Song, Hui-Qun,Zhu, Xing-Quan,Petersen, Eskild,Petersen, Eskild,Zhu, Xing-Quan. 2013

[9]Sequence Variation in ROP9 Gene among Toxoplasma gondii Strains from Different Hosts and Geographical Locations. Chen, Jia,Li, Zhong-Yuan,Fang, Su-Fang,Chen, Jia,Li, Zhong-Yuan,Zhou, Dong-Hui,Liu, Guo-Hua,Zhu, Xing-Quan,Liu, Guo-Hua,Zhu, Xing-Quan. 2012

[10]Sequence variation in Toxoplasma gondii MIC13 gene among isolates from different hosts and geographical locations. Ren, Di,Zhou, Yang,Lin, Ze-Ping,Lin, Rui-Qing,Wu, Song-Ming,Lin, Shao-Qi,Yuan, Zi-Guo,Ren, Di,Zhou, Dong-Hui,Xu, Min-Jun,Zhou, Yang,Wu, Song-Ming,Yuan, Zi-Guo,Yang, Jian-Fa,Zou, Feng-Cai. 2012

[11]Genetic characterization of Toxoplasma gondii from pigs from different localities in China by PCR-RFLP. Jiang, Hai-Hai,Huang, Si-Yang,Zhou, Dong-Hui,Zhang, Xiao-Xuan,Su, Chunlei,Zhu, Xing-Quan,Deng, Shun-Zhou,Su, Chunlei,Zhang, Xiao-Xuan. 2013

[12]Sequence variation in the Toxoplasma gondii ROP20 gene among strains from different hosts and geographical locations. Ning, H. R.,Zhu, X. Q.,Ning, H. R.,Wang, J. L.,Qin, S. Y.,Huang, S. Y.,Lou, Z. L.,Hu, L. Y.,Zhu, X. Q.,Qin, S. Y.,Lou, Z. L.,Huang, S. Y.,Zhu, X. Q.. 2015

[13]Seroprevalence and genetic characterization of Toxoplasma gondii in three species of pet birds in China. Cong, Wei,Song, Hui-Qun,Zhou, Dong-Hui,Huang, Si-Yang,Su, Chunlei,Zhu, Xing-Quan,Cong, Wei,Qian, Ai-Dong,Zhu, Xing-Quan,Meng, Qing-Feng,Su, Chunlei. 2014

[14]Recent advances in developing vaccines against Toxoplasma gondii: an update. Zhang, Nian-Zhang,Wang, Meng,Xu, Ying,Zhu, Xing-Quan,Xu, Ying,Petersen, Eskild. 2015

[15]Protective efficacy of Toxoplasma gondii calcium-dependent protein kinase 1 (TgCDPK1) adjuvated with recombinant IL-15 and IL-21 against experimental toxoplasmosis in mice. Chen, Jia,Li, Zhong-Yuan,Huang, Si-Yang,Song, Hui-Qun,Zhou, Dong-Hui,Zhu, Xing-Quan,Chen, Jia,Zhu, Xing-Quan,Petersen, Eskild,Petersen, Eskild. 2014

[16]Comparative characterization of microRNA profiles of different genotypes of Toxoplasma gondii. Xu, M. J.,Zhou, D. H.,Huang, S. Y.,Zhao, F. R.,Song, H. Q.,Zhu, X. Q.,Xu, M. J.,Zhou, D. H.,Huang, S. Y.,Zhao, F. R.,Song, H. Q.,Zhu, X. Q.,Nisbet, A. J.,Lin, R. Q.,Zhu, X. Q.. 2013

[17]Genetic diversity among Toxoplasma gondii strains from different hosts and geographical regions revealed by sequence analysis of GRA5 gene. Chen, Jia,Li, Zhong-Yuan,Zhou, Dong-Hui,Liu, Guo-Hua,Zhu, Xing-Quan,Chen, Jia,Li, Zhong-Yuan,Liu, Guo-Hua,Zhu, Xing-Quan. 2012

[18]Characterization of the Toxoplasma gondii hsp60 gene sequences from different hosts and geographical locations. Lu, J.,Zhou, D. H.,Chen, J.,Zhang, N. Z.,Wang, R. A.,Zhu, X. Q.,Lu, J.,Wang, R. A.,Weng, Y. B.. 2014

[19]Nucleotide variation in the Toxoplasma gondii micronemal protein 8 gene. Li, Z. Y.,Wang, C. R.,Zhu, X. Q.,Li, Z. Y.,Song, H. Q.,Zhu, X. Q.. 2016

[20]Toxoplasma gondii: Bioinformatics analysis, cloning and expression of a novel protein TgIMP1. Bai, Yang,He, Shenyi,Zhao, Guanghui,Chen, Lin,Shi, Na,Zhou, Huaiyu,Cong, Hua,Zhao, Qunli,Bai, Yang,He, Shenyi,Zhao, Guanghui,Chen, Lin,Shi, Na,Zhu, Xing-Quan,Zhu, Xing-Quan.

作者其他论文 更多>>