Identification of Major Metabolites of Salbutamol in Swine Urine and Plasma Using Ultra-High Performance Liquid Chromatography-Electrospray Time of Flight Mass Spectrometry
文献类型: 外文期刊
作者: Gu Xu;Liu Yi-Ming;Yao Ting;Shi Hua-Le;Li Jun;Zhao Zhen;Qin Yu-Chang
作者机构:
关键词: Salbutamol;Ultra-high performance liquid chromatography-electrospray time of flight mass spectrometry;Metabolites
期刊名称: CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
ISSN: 0253-3820
年卷期: 2014 年 42 卷 11 期
页码:
收录情况: SCI
摘要: The excretion of urinary and plasmic metabolites of salbutamol was studied using ultra performance liquid chromatography electrospray ionization quadrupole time-of-flight tandem mass spectrometry, after a single intragastric gavaged dose administration with salbutamol. The software of Agilent Mass Hunter Metabolite ID was employed to find and identify the chemical structure of metabolites of salbutamol. Five metabolites from salbutamol were identified. The metabolites identified in swine urine included glucuronide conjugate salbutamol, N-oxide-salbutamol, hydroxyl-salbutamol, methoxyl-salbutamol and dehydrated hydroxyl-salbutamol. Whereas, only the parent drugs, glucuronide conjugate salbutamol and N-oxide salbutamol were observed in plasma.
分类号:
- 相关文献
作者其他论文 更多>>
-
Mixed vaginal infection status in women infected with Trichomonas vaginalis: comparison of microscopy method and metagenomic sequencing analysis
作者:Li Jun;Xiulin Wan;Dai Zhang;Yan Zheng;Xi Chen;Lan Mi;Bingbing Xiao
关键词:community state type (CST) classification;metagenomic sequence;mixed vaginitis;vaginal microbiome;Vaginal trichomoniasis
-
Predicting the chemical composition of pet food with hyperspectral imaging
作者:Liu Xiaolu;Li Shouxue;Yao Ting;Feng Yuchao;Yao Shujiao;Fan Xia
关键词:Cat food;Dog food;Hyperspectral imaging;Partial least squares regression
-
Genome-Wide Identification and Evolutionary Analysis of the Fruit-Weight 2.2-Like Gene Family in Polyploid Oilseed Rape (Brassica napus L.)
作者:Kuang Chen;Li Jun;Liu Hongfang;Liu Jun;Sun Xingchao;Zhu Xiaoyi;Hua Wei
关键词:
-
Effect Of Season And Breed O.n Physiological And Blood P arameters In Buffaloes
作者:Deng Tingxian;Rehman, Zia Ur;Li Jun;Li Zipeng;Zhou Zichao;Liu Shenhe;Yang Liguo
关键词:Crossbred buffalo; Mediterranean buffalo; THI; heat tolerance
-
Rapid And Convenient Transformation Of C.otton (Gossypium Hirsutum L.) U sing In Planta Shoot Apex Via Glyphosate Selection
作者:Wang, Kevin Yueju;Guo Wen-Fang;Wang Nan;Liu De-Hu;Li Gang-Qiang;Li Jun
关键词:shoot apex transformation; CP4-EPSPS; glyphosate; in planta; transgenic cotton
-
A Visual Gel-Enzyme-Linked Immunosorbent Assay for Simultaneous Detection of Gentamicin and Kanamycin in Milk
作者:Xu Fei;Liu Mao-Lin;Liu Yi-Ming;Li Xiu-Bo;Li Jing-Ya;Zhou Jie;Ding Shuang-Yang;Wang Jian-Fen
关键词:Gel-enzyme-linked immunosorbent assay;Gentamicin;Kanamycin;Simultaneous detection;Milk
-
Immunoassay of chemical contaminants in milk: A review
作者:Xu Fei;Liu Yi-ming;Li Xiu-bo;Ren Kang;Yang Yu-ze;Guo Jiang-peng;Lu Yong-qiang;Ma Guang-peng
关键词:milk;chemical contaminants;immunoassay;antibodies