数字农科院2.0

Comparative proteomic changes of differentially expressed whey proteins in clinical mastitis and healthy yak cows

文献类型： 外文期刊

作者： Li, X.;Du, G. Z.;Li, X.;Ding, X. Z.;Liu, Y. M.;Wan, Y. L.

作者机构：

关键词： Mastitis;Milk proteins;Two-dimensional gel electrophoresis

期刊名称： GENETICS AND MOLECULAR RESEARCH

ISSN： 1676-5680

年卷期： 2014 年 13 卷 3 期

页码：

收录情况： SCI

摘要： Under the traditional grazing system on the Qinghai-Tibetan Plateau, the amount of milk in domesticated yak (Bos grunniens) with clinical mastitis decreases and the milk composition is altered. To understand the mechanisms of mammary gland secreted milk and disease infection, changes in the protein composition of milk during clinical mastitis were investigated using a proteomic approach. Milk whey from yak with clinical mastitis was compared to whey from healthy animals with two-dimensional gel electrophoresis using a mass spectrometer. Thirteen protein spots were identified to be four differentially expressed proteins. Increases in the concentrations of proteins of blood serum origin, including lactoferrin, were identified in mastitic whey compared to normal whey, while concentrations of the major whey proteins, casocidin-I, a-lactalbumin, and b-lactoglobulin, were downregulated in mastitic whey. These results indicated significant differences in protein expression between healthy yaks and those with clinical mastitis, and they may provide valuable information for finding new regulation markers and potential protein targets for the treatment of mastitis.

分类号：

  • 相关文献

[1]Comparative Analysis of Skim Milk and Milk Fat Globule Membrane Proteomes between Human and Farm Animal Milk for Infant Formula Production. Zhang, Wenyuan,Chen, Baorong,Zhu, Huiquan,Hettinga, Kasper,Pang, Xiaoyang,Zhang, Shuwen,Li, Kaifeng,Jiang, Shilong,Lyu, Jiaping. 2024

[2]Proteomic analysis of differentially expressed proteins between the male and female worm of Schistosomal japonicum after pairing. Cheng, GF,Lin, JJ,Feng, XG,Fu, ZQ,Jin, YM,Yuan, CX,Zhou, YC,Cai, YM. 2005

[3]Analysis of Developmental Proteome at Egg Stage of Drone Honeybees (A. m. ligustica). Fang Yu,Li Jian-ke. 2010

[4]Characterization of the chaperonin GroEL in Mycoplasma gallisepticum. Tan, Lei,Hu, Meirong,Yu, Shengqing,Wang, Xin,Lu, Feng,Liu, Fang,Qiu, Xusheng,Song, Cuiping,Sun, Yingjie,Ding, Chan.

[5]Proteomic Analysis of Proteins in the Salivary Glands of the Fed and Unfed Female Tick Rhipicephalus haemaphysaloides. Xiang Fei-yu,Zhang Jian-wu,Zhou Yong-zhi,Li Zhuang,Gong Hai-yan,Zhou Jin-lin,Xiang Fei-yu. 2009

[6]Comparative proteomic analyses reveal the changes of metabolic features in soybean (Glycine max) pistils upon pollination. Li, Ming,Yang, Pingfang,Li, Ming,Sha, Aihua,Zhou, Xinan.

[7]Research on Root Responses to Pb and Zn Combined Stress of Carex putuoshan. Hu, Yong-Lin,Tan, Jia-Lang,Yang, Zhan-Biao,Yang, Yuan-Xiang,Chen, Zhang,Lin, Li-Jin,Wang, Ying-Jun,Sun, Gang,Zhu, Xue-Mei,Wang, Cheng-Long,Shao, Ji-Rong,Zhou, Mei-Liang.

[8]BP5 regulated B cell development promoting anti-oxidant defence. Liu, Xiao-Dong,Zhou, Bin,Cao, Rui-Bing,Feng, Xiu-Li,Chen, Pu-Yan,Ma, Zhi-Yong.

[9]Comparative Analyses of Proteome Complement Between Worker Bee Larvae of High Royal Jelly Producing Bees (A. m. ligustica) and Carniolian Bees (A. m. carnica). Chen Jian,Li Jian-ke. 2009

[10]Proteome Analysis of Tea Pollen (Camellia sinensis) under Different Storage Conditions. Zhang, Zhaohui,Pan, Yinghong,Li, Jianke,Chen, Jian,Chen, Jian.

[11]Towards posttranslational modification proteome of royal jelly. Zhang, Lan,Fang, Yu,Li, Rongli,Feng, Mao,Han, Bin,Zhou, Tiane,Li, Jianke.

[12]Comparative Proteomic Analysis of Yak Follicular Fluid during Estrus. Guo, Xian,Pei, Jie,Ding, Xuezhi,Chu, Min,Bao, Pengjia,Wu, Xiaoyun,Liang, Chunnian,Yan, Ping.

[13]Identification mutation of the CACNA2D1 gene and its effect on somatic cell score in cattle. Deng, Gui-xin,Yuan, Zheng-rong,Gao, Xue,Li, Jun-ya,Chen, Jin-bao,Gao, Hui-jiang,Xu, Shang-zhong. 2011

[14]Identification of CD14 transcript in blood polymorphonuclear neutrophil leukocytes and functional variation in Holsteins. Huang, J. M.,Hao, H. S.,Zhu, H. B.,Huang, J. M.,Wang, X. G.,Jiang, Q.,Sun, Y.,Yang, C. H.,Ju, Z. H.,Wang, C. F.,Zhong, J. F.. 2016

[15]Inflammatory Response of Peripheral Blood Mononuclear Cells Post Intramammary Challenge with Staphylococcus aureus in Dairy Cows. Liu, Li,Yuan, Zhengrong,Chen, Cui,Zhang, Limin,Chen, Xiaojie,Liu, Xidong,Gao, Xue,Li, Junya,Gao, Huijiang,Zhang, Lupei,Xu, Shangzhong. 2012

[16]Investigation on BRCA1 SNPs and its effects on mastitis in Chinese commercial cattle. Yuan, Zhengrong,Li, Junya,Li, Jiao,Zhang, Lupei,Gao, Xue,Gao, Hui Jiang,Xu, Shangzhong,Yuan, Zhengrong.

[17]Comparative proteomics analysis of plasma proteins during the transition period in dairy cows with or without subclinical mastitis after calving. Yang, Y. X.,Wang, J. Q.,Bu, D. P.,Li, S. S.,Yuan, T. J.,Zhou, L. Y.,Yang, J. H.,Sun, P.,Yang, Y. X..

[18]SNPs identification and its correlation analysis with milk somatic cell score in bovine MBL1 gene. Yuan, Zhengrong,Li, Jiao,Li, Junya,Gao, Xue,Xu, Shangzhong,Yuan, Zhengrong,Yuan, Zhengrong.

[19]Toll-Like Receptor 2 Gene Polymorphism and its Relationship with SCS in Dairy Cattle. Zhang, L. P.,Li, H. D.,Li, J. Y.,Gao, X.,Chen, J. B.,Ren, H. Y.,Xu, S. Z.,Gan, Q. F.,Wang, X. P.,Xu, S. Z.,Ma, T. H.. 2009

[20]Haplotype analysis of TLR4 gene and its effects on milk somatic cell score in Chinese commercial cattle. Wang, Xing Ping,Zhuo Ma Luoreng,Guo, Dong Sheng,Li, Feng,Chen, Gang,Wang, Jin Ren,Gao, Shu Xin,Li, Jun Ya,Gao, Xue,Xu, Shang Zhong.

作者其他论文 更多>>