数字农科院2.0

Resequencing of 31 wild and cultivated soybean genomes identifies patterns of genetic diversity and selection

文献类型： 外文期刊

作者： Lam, Hon-Ming;Liu, Xin;Wong, Fuk-Ling;Li, Man-Wah;Shao, Guihua;Sun, Samuel Sai-Ming;Xu, Xun;Zhang, Gengyun;Shao, Guihua;Wang, Jun;Lam, Hon-Ming;Liu, Xin;Wong, Fuk-Ling;Li, Man-Wah;Shao, Guihua;Sun, Samuel Sai-Ming

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期刊名称： NATURE GENETICS

ISSN： 1061-4036

年卷期： 2010 年 42 卷 12 期

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收录情况： SCI

摘要： We report a large-scale analysis of the patterns of genome-wide genetic variation in soybeans. We re-sequenced a total of 17 wild and 14 cultivated soybean genomes to an average of approximately x5 depth and > 90% coverage using the Illumina Genome Analyzer II platform. We compared the patterns of genetic variation between wild and cultivated soybeans and identified higher allelic diversity in wild soybeans. We identified a high level of linkage disequilibrium in the soybean genome, suggesting that marker-assisted breeding of soybean will be less challenging than map-based cloning. We report linkage disequilibrium block location and distribution, and we identified a set of 205,614 tag SNPs that may be useful for QTL mapping and association studies. The data here provide a valuable resource for the analysis of wild soybeans and to facilitate future breeding and quantitative trait analysis.

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