数字农科院2.0

Interactive effects of chlorothalonil and Varroa destructor on Apis mellifera during adult stage

文献类型： 外文期刊

作者： Tong Wu;Yong Soo Choi;Dong Won Kim;Xiaoping Wei;Yuxin Kang;Bo Han;Sa Yang;Jing Gao;Pingli Dai

作者机构：

关键词： Chlorothalonil;Fat body;Honey bee;Survival;Varroa destructor

期刊名称： Pesticide Biochemistry and Physiology

ISSN： 0048-3575

年卷期： 2024 年 204 卷

页码：

收录情况： SCIE（2024版）

摘要： The interaction between environmental factors affecting honey bees is of growing concern due to their potential synergistic effects on bee health. Our study investigated the interactive impact of Varroa destructor and chlorothalonil on workers' survival, fat body morphology, and the expression of gene associated with detoxification, immunity, and nutrition metabolism during their adult stage. We found that both chlorothalonil and V. destructor significantly decreased workers' survival rates, with a synergistic effect observed when bees were exposed to both stressors simultaneously. Morphological analysis of fat body revealed significant alterations in trophocytes, particularly a reduction in vacuoles and granules after Day 12, coinciding with the transition of the bees from nursing to other in-hive work tasks. Gene expression analysis showed significant changes in detoxification, immunity, and nutrition metabolism over time. Detoxification genes, such as CYP9Q2, CYP9Q3, and GST-D1, were downregulated in response to stressor exposure, indicating a potential impairment in detoxification processes. Immune-related genes, including defensin-1, Dorsal-1, and Kayak, exhibited an initially upregulation followed by varied expression patterns, suggesting a complex immune response to stressors. Nutrition metabolism genes, such as hex 70a, AmIlp2, VGMC, AmFABP, and AmPTL, displayed dynamic expression changes, reflecting alterations in nutrient utilization and energy metabolism in response to stressors. Overall, these findings highlight the interactive and dynamic effects of environmental stressor on honey bees, providing insights into the mechanisms underlying honey bee decline. These results emphasize the need to consider the interactions between multiple stressors in honey bee research and to develop management strategies to mitigate their adverse effects on bee populations.

分类号：

  • 相关文献

[1]Interaction of chlorothalonil and Varroa destructor on immature honey bees rearing in vitro. Tong Wu,Jing Gao,Yong Soo Choi,Dong Won Kim,Bo Han,Sa Yang,Ying Lu,Yuxin Kang,Hanchao Du,Qingyun Diao,Pingli Dai. 2023

[2]Honey vs. Mite-A Trade-Off Strategy by Applying Summer Brood Interruption for Varroa destructor Control in the Mediterranean Region. Kovacic, Marin,Uzunov, Aleksandar,Gajger, Ivana Tlak,Pietropaoli, Marco,Soroker, Victoria,Adjlane, Noureddine,Benko, Valerija,Charistos, Leonidas,Dall'Olio, Raffaele,Formato, Giovanni,Hatjina, Fani,Malagnini, Valeria,Freda, Fabrizio,Otmi, Asaf,Puskadija, Zlatko,Villar, Claudio,Buechler, Ralph. 2023

[3]Data from expressed sequence tags from the organs and embryos of parthenogenetic Haemaphysalis longicornis. Rika Umemiya-Shirafuji,Jinlin Zhou,Min Liao,Badgar Battsetseg,Damdinsuren Boldbaatar,Takeshi Hatta,Thasaneeya Kuboki,Takeshi Sakaguchi,Huey Shy Chee,Takeharu Miyoshi,Xiaohong Huang,Naotoshi Tsuji,Xuenan Xuan,Kozo Fujisaki. 2021

[4]SPARC plays an important role in the oviposition and nymphal development in Nilaparvata lugens Stål. Weixia Wang,Tingheng Zhu,Pinjun Wan,Qi Wei,Jiachun He,Fengxiang Lai,Qiang Fu. 2022

[5]Untargeted Lipidomics Analysis Unravels the Different Metabolites in the Fat Body of Mated Bumblebee (Bombus terrestris) Queens. Yueqin Guo,Fugang Liu,Yulong Guo,Yingping Qu,Zhengyi Zhang,Jun Yao,Jin Xu,Jilian Li. 2023

[6]Residues and dissipation of chlorothalonil and azoxystrobin in cabbage under field conditions. Hou, Fan,Liu, Fengmao,Zhao, Liuwei.

[7]Proteome Analysis of the Hemolymph, Mushroom Body, and Antenna Provides Novel Insight into Honeybee Resistance against Varroa Infestation. Hu, Han,Hao, Yue,Feng, Mao,Han, Bin,Fang, Yu,Wubie, Abebe Jenberie,Li, Jianke,Bienefeld, Kaspar,Wegener, Jakob,Zautke, Fred.

[8]Chlorothalonil Inhibits Mouse Ovarian Development T.hrough Endocrine Disruption. Hao, Y, Zhang, HF, Zhang, PF, Yu, S, Ma, DX, Li, L, Feng, YN, Min, LJ, Shen, W, Zhao, Y. 2019

[9]Chlorothalonil alters the gut microbiota and reduces the survival of immature honey bees reared in vitro. Wu, Tong,Han, Bo,Wang, Xing,Tong, Yuemin,Liu, Feng,Diao, Qingyun,Dai, Pingli. 2021

[10]Low Dose Chlorothalonil Impairs Mouse S.permatogenesis Through The Intertwining O f Estrogen Receptor Pathways With Histone And Dna Methylation. Zhang, PF, Zhao, Y, Zhang, HF, Liu, J, Feng, YN, Yin, S, Cheng, SF, Sun, XF, Min, LJ, Li, L, Shen, W. 2019

[11]Significant Transcriptional Changes In Mature Daughtervarroa Destructormites During Infestation Of Different Developmental Stages Of Honeybees. Wu, JL, Elsheikha, HM, Tu, YY, Getachew, A, Zhou, HY, Zhou, CX, Xu, SF. 2020

[12]Exposure of chlorothalonil and acetamiprid reduce the survival and cause multiple internal disturbances in Apis mellifera larvae reared in vitro. Ying Lu,Jing Gao,Tong Wu,Bo Han,Bingnan Qian,Min Shi,Sa Yang,Qingyun Diao,Chunya Bu,Pingli Dai. 2023

[13]Transmission of deformed wing virus (DWV) between Apis mellifera and Tropilaelaps mercedesae. Yang, Sa,Luo, Qihua,Wu, Yanyan,Gao, Jing,Dai, Pingli. 2024

[14]Use of Transcriptomics to Reveal the Joint Immunotoxicity Mechanism Initiated by Difenoconazole and Chlorothalonil in the Human Jurkat T-Cell Line. Li Y.-C.,Liu S.-Y.,Li H.-R.,Meng F.-B.,Qiu J.,Qian Y.-Z.,Xu Y.-Y.. 2024

[15]Interaction of acetamiprid, Varroa destructor, and Nosema ceranae in honey bees. Kang Y.,Wu T.,Han B.,Yang S.,Wang X.,Wang Q.,Gao J.,Dai P.. 2024

[16]Sulfhydrylation of chlorothalonil in pak choi from cultivation to sample analysis and exposure risk assessment. Cao, Yi-Lin,Li, Nan,Li, Yun,Qiu, Jing,Sui, Hai-Xia,Yang, Dao-Yuan,Qian, Yong-Zhong. 2025

[17]Varroa destructor infestation amplifies imidacloprid vulnerability in Apis mellifera. Yinchen Wang,Xijie Li,Chunhui Miao,Chonghui Zhao,Jun Zhang,Yantao Pang,Junjie Li,Richan Fang,Xueyi Shen,Ying Lin,Tian Zhao,Mengqing Deng,Luansong Zhang,Hua Wang,Wanli Li,Jun Guo. 2025

[18]Effect of different prey species on the life history parameters of Chrysoperla sinica (Neuroptera: Chrysopidae). Chen, Hongyin. 2012

[19]Puccinia striiformis f.sp tritici presents high diversity and recombination in the over-summering zone of Gansu, China. Enjalbert, J.,Duan, X.,Tellier, A.,Wan, A.,Leconte, M.,de Vallavielle-Pope, C.. 2010

[20]CRYOPRESERVATION OF IN VITRO-GROWN SHOOT TIPS OF CHINESE MEDICINAL PLANT Atractylodes macrocephala KOIDZ. USING A DROPLET-VITRIFICATION METHOD. Zhang, Jin-mei,Lu, Xin-xiong,Xin, Xia,Yin, Guang-kun,He, Juan-juan,Chen, Xiao-ling,Huang, Bin,Volk, Gayle M.. 2015

作者其他论文 更多>>